Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s315_54V6.1 |
Family | GT8 |
Protein Properties | Length: 492 Molecular Weight: 55241.7 Isoelectric Point: 8.454 |
Chromosome | Chromosome/Scaffold: 315 Start: 345605 End: 348947 |
Description | Nucleotide-diphospho-sugar transferases superfamily protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT8 | 58 | 245 | 5.8e-25 |
DYEFYIAARVMLGTLVRFQVDADLVVIASESVPPQWQKTLTDEGAKVVVVSDIQNPYANYRNFDKRFLLTLNKIYAWSLTEYQRVVMLDADNLFLRAPDE LFQCGQFCAAFINPCIFHTGLFVLQPSNETFSNMMHDISIGKESSDGADQGFLASHFTDLLDRPMFHPPADGSRLDGLFRLPLGYQMD |
Full Sequence |
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Protein Sequence Length: 492 Download |
MENRNGKTAQ FRLSVALFWV STLLTGAAFS SHAAHAPLKG TLKANAYATM LYMGTPRDYE 60 FYIAARVMLG TLVRFQVDAD LVVIASESVP PQWQKTLTDE GAKVVVVSDI QNPYANYRNF 120 DKRFLLTLNK IYAWSLTEYQ RVVMLDADNL FLRAPDELFQ CGQFCAAFIN PCIFHTGLFV 180 LQPSNETFSN MMHDISIGKE SSDGADQGFL ASHFTDLLDR PMFHPPADGS RLDGLFRLPL 240 GYQMDASFFY LKLKWRVPCG PNSVITFPSV PMLKPWYWWS WPILPLGLSW HEKRVATIGY 300 ETESPVLIAE SLFYIFIMLV ALIIRQRYAC SEKSSMSRIT CFGRGPCAEK KLCHPWAIKL 360 IILALVAGSF RLPFYMIPTT VHPLMGWGVF LLGSFCLLTV VNTAFQLPDL PVLTPWLGCI 420 GALFTMGSPF YASGITRGLG IGIYVAMITP FLWWAAKRVS GVVHAKVYWE PLMAWNSVRS 480 EPASETLMKL C* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd06914 | GT8_GNT1 | 0.0001 | 128 | 276 | 163 | + GNT1 is a fungal enzyme that belongs to the GT 8 family. N-acetylglucosaminyltransferase is a fungal enzyme that catalyzes the addition of N-acetyl-D-glucosamine to mannotetraose side chains by an alpha 1-2 linkage during the synthesis of mannan. The N-acetyl-D-glucosamine moiety in mannan plays a role in the attachment of mannan to asparagine residues in proteins. The mannotetraose and its N-acetyl-D-glucosamine derivative side chains of mannan are the principle immunochemical determinants on the cell surface. N-acetylglucosaminyltransferase is a member of glycosyltransferase family 8, which are, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed, retaining glycosyltransferases. | ||
COG5597 | COG5597 | 2.0e-5 | 41 | 216 | 192 | + Alpha-N-acetylglucosamine transferase [Cell envelope biogenesis, outer membrane] | ||
cd00505 | Glyco_transf_8 | 1.0e-5 | 126 | 210 | 112 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. | ||
pfam01501 | Glyco_transf_8 | 1.0e-8 | 79 | 210 | 167 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. | ||
cd02537 | GT8_Glycogenin | 6.0e-65 | 45 | 294 | 260 | + Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen. Glycogenin initiates the biosynthesis of glycogen by incorporating glucose residues through a self-glucosylation reaction at a Tyr residue, and then acts as substrate for chain elongation by glycogen synthase and branching enzyme. It contains a conserved DxD motif and an N-terminal beta-alpha-beta Rossmann-like fold that are common to the nucleotide-binding domains of most glycosyltransferases. The DxD motif is essential for coordination of the catalytic divalent cation, most commonly Mn2+. Glycogenin can be classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. It is placed in glycosyltransferase family 8 which includes lipopolysaccharide glucose and galactose transferases and galactinol synthases. |
Gene Ontology | |
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GO Term | Description |
GO:0016757 | transferase activity, transferring glycosyl groups |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAH67416.1 | 0 | 43 | 401 | 40 | 388 | OSIGBa0143N19.10 [Oryza sativa (indica cultivar-group)] |
RefSeq | XP_001752682.1 | 0 | 50 | 491 | 1 | 455 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001757794.1 | 0 | 38 | 491 | 15 | 468 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001777225.1 | 0 | 53 | 491 | 1 | 445 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001781942.1 | 0 | 50 | 491 | 1 | 442 | predicted protein [Physcomitrella patens subsp. patens] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3u2x_B | 0.000000000000002 | 64 | 215 | 19 | 173 | A Chain A, Active Site Structural Features For Chemically Modified Forms Of Rhodanese |
PDB | 3u2x_A | 0.000000000000002 | 64 | 215 | 19 | 173 | A Chain A, Active Site Structural Features For Chemically Modified Forms Of Rhodanese |
PDB | 3u2v_B | 0.000000000000002 | 64 | 215 | 19 | 173 | A Chain A, Active Site Structural Features For Chemically Modified Forms Of Rhodanese |
PDB | 3u2v_A | 0.000000000000002 | 64 | 215 | 19 | 173 | A Chain A, Active Site Structural Features For Chemically Modified Forms Of Rhodanese |
PDB | 3u2u_B | 0.000000000000002 | 64 | 215 | 19 | 173 | A Chain A, Active Site Structural Features For Chemically Modified Forms Of Rhodanese |