Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s326_70V6.1 |
Family | GT47 |
Protein Properties | Length: 509 Molecular Weight: 57241.4 Isoelectric Point: 9.3776 |
Chromosome | Chromosome/Scaffold: 326 Start: 431298 End: 433212 |
Description | exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 119 | 439 | 0 |
ARLKVFMYDLPSEFHYGMISEFTPKKNQIWPQNVSDIPKYPGGLYQQHSPEYWLISDLVTSDMPDRSTPCTVFRVKRWQDAGVILIPFFASLSYNKYSRA PLLRGKKLDRNQELQLNLISFLSSQPAWRASEGSNHVVVIHHPNAMLHTREKFRSVMFVVADFGRYGAEVANMAKDVVAPYKHVIPNFDEDVDAALSFKS RTTLLFFQGAIARKEGGIIRQQLYELLGEEPNIIFSNGTTSNAGIRSATAGMRQSKFCLHLAGDTPSSNRLFDAVASHCVPLIISNEIELPFEDVLNYSE FSLFVNSSDALRKGFVTDLLS |
Full Sequence |
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Protein Sequence Length: 509 Download |
MWRPVQAGRT GKNMDSREDD DDLAAKVKPL RIGYSSWISK GYIVAALALV LLTLLSGVLT 60 TDLSHSSGVP VVLKYVRAFK SEMLDLKSEV ELKEPDSGSL QFSNPSNASK QAGCHKDSAR 120 LKVFMYDLPS EFHYGMISEF TPKKNQIWPQ NVSDIPKYPG GLYQQHSPEY WLISDLVTSD 180 MPDRSTPCTV FRVKRWQDAG VILIPFFASL SYNKYSRAPL LRGKKLDRNQ ELQLNLISFL 240 SSQPAWRASE GSNHVVVIHH PNAMLHTREK FRSVMFVVAD FGRYGAEVAN MAKDVVAPYK 300 HVIPNFDEDV DAALSFKSRT TLLFFQGAIA RKEGGIIRQQ LYELLGEEPN IIFSNGTTSN 360 AGIRSATAGM RQSKFCLHLA GDTPSSNRLF DAVASHCVPL IISNEIELPF EDVLNYSEFS 420 LFVNSSDALR KGFVTDLLSN VGEKEWTRMH DRLRQVERHF QYQLPAQIGD AVHMTWEAIA 480 RKVPALTLAR NKQRRYARSQ FISQKIAT* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-48 | 119 | 423 | 313 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_001758016.1 | 0 | 114 | 500 | 92 | 479 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001759885.1 | 0 | 121 | 496 | 1 | 383 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001768834.1 | 0 | 136 | 503 | 1 | 368 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001773896.1 | 0 | 125 | 496 | 1 | 369 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001782303.1 | 0 | 83 | 508 | 1 | 426 | predicted protein [Physcomitrella patens subsp. patens] |