Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s34_108V6.1 |
Family | GT47 |
Protein Properties | Length: 301 Molecular Weight: 34576.8 Isoelectric Point: 9.6968 |
Chromosome | Chromosome/Scaffold: 34 Start: 568458 End: 570096 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 89 | 294 | 1.7e-36 |
LNIYVYEMPAKFTTDLLWLFHNSLDQTVNLTSNGSPVHRLIQQHSVDFWLFSDLMTREDKRLLKTFRRVSHQEQADVYYVPFFTTIPFFLLSRVQSRTLY REAVKWITRQAAWQRSGGRDHVLAVHHPWSMKSHRRFLKSAIWLLSDLDSSGNWYKEGEVSLEKDVIMPYVANVDACDDNCLATSKPSRKTLLFFQGRIV RGSVKQ |
Full Sequence |
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Protein Sequence Length: 301 Download |
MSRKVSRLWA VLLFLVMAWS TWNATDYFPR NLHPTVNTPE ISFLASLHGF LMKHAEISWK 60 VSVDSPGIAV HGEGIDRSPG SIPTSPPTLN IYVYEMPAKF TTDLLWLFHN SLDQTVNLTS 120 NGSPVHRLIQ QHSVDFWLFS DLMTREDKRL LKTFRRVSHQ EQADVYYVPF FTTIPFFLLS 180 RVQSRTLYRE AVKWITRQAA WQRSGGRDHV LAVHHPWSMK SHRRFLKSAI WLLSDLDSSG 240 NWYKEGEVSL EKDVIMPYVA NVDACDDNCL ATSKPSRKTL LFFQGRIVRG SVKQCCMSLL 300 * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-27 | 85 | 290 | 210 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAF06505.2 | 0 | 40 | 291 | 61 | 315 | Os01g0811400 [Oryza sativa Japonica Group] |
GenBank | EAY76230.1 | 0 | 40 | 291 | 62 | 316 | hypothetical protein OsI_04166 [Oryza sativa Indica Group] |
RefSeq | NP_001044591.1 | 0 | 40 | 291 | 61 | 315 | Os01g0811400 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_197191.1 | 0 | 14 | 291 | 31 | 320 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_001758873.1 | 0 | 52 | 294 | 1 | 243 | predicted protein [Physcomitrella patens subsp. patens] |