y
Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s351_36V6.1 |
Family | GT8 |
Protein Properties | Length: 1074 Molecular Weight: 121074 Isoelectric Point: 5.0594 |
Chromosome | Chromosome/Scaffold: 351 Start: 293134 End: 299104 |
Description | plant glycogenin-like starch initiation protein 2 |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT8 | 755 | 969 | 5.70001e-40 |
HKEAYVTILHSGADYVCGAIVTAHSIRKTGSTKDLVILVDSSISPEQRQALGEAGWEVRDLERIYKSNIVEGKQCEKDFSRFRLWQITDYNKVVYVEADV LVLRNLDHLFSMPEISASGSTKTLFNSGVMVVEPSNCTFQLLMDEMEKIISETGGDWDFFNRIFPWWHRIPKHMNYLKYFWTRSRTSEVDSSNRLFSAEP PQLYAIHYWGYKPWQ |
Full Sequence |
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Protein Sequence Length: 1074 Download |
MENNMKENWK QEMWERSRDR IAEIYQRVSS IDIEAFLKTS IIGIVGKDII EHARRKTSVV 60 RNAGKNMLYQ ARQKYDSKGL EKHLKLRKFV AGIRSGRLGY LLLVLAALCT LTVPLMFQST 120 YIPQEDWELE RAMAIQFHQG RGVDETFNRK MKLAQEKNLI YEEGKKSSEI SHRWNSGQVG 180 REVSGGHDAY ILDSEVNIFA GKNERQHKVI STKPATRGRN RSKRYNIIEE VIKRALEKST 240 AGFDEKETEQ DIKLDSHAVV LSEKTMSLSD TQESLNMTPL RANSTVDSEG LSNGFSEAFN 300 EVLKLASEAN KTAGKHSVHL QEEASVTESL PTHKPAELDV QVREVVDRAS QKLSEAEDEP 360 SGKGTIASFG LYSEENKENV SVGEGMEASH NTPQTKPMFA KNVEEGKSEL LKSNSMEDKD 420 KHQTNILSGN EGNTLIQTQT STASRDSDVV MANVGKVKSM DLSTENVDNS NELKIIQGRD 480 PEVTVVESSR EAGNSLENSS ESIVNATETN NNFTSMKDED DIKVVGVMDG EKLDDDAAEE 540 QELQAEVRQE NSDEWPQESA LISSLRLRAT SGTLRVGLLN MEATDFLRWQ FLAGERPIII 600 PFERVNEAVD WNQLYPEWID EEETYGAPIC PAIPMPKISP EVQLDVVIAR VPCASSALQE 660 GWKQPASLQV LLGAASLAVN AGNGSIYVLI LSECRPLVNL FSCGELLEHR DQGWLYQVNV 720 EQLKKRTSMS VGSCQLSIPL RGQDTSLDTG ASNLHKEAYV TILHSGADYV CGAIVTAHSI 780 RKTGSTKDLV ILVDSSISPE QRQALGEAGW EVRDLERIYK SNIVEGKQCE KDFSRFRLWQ 840 ITDYNKVVYV EADVLVLRNL DHLFSMPEIS ASGSTKTLFN SGVMVVEPSN CTFQLLMDEM 900 EKIISETGGD WDFFNRIFPW WHRIPKHMNY LKYFWTRSRT SEVDSSNRLF SAEPPQLYAI 960 HYWGYKPWQC FRDYDCNWNS NNHFASDEAH ARWFKVYDEL PENLQKFCSL STGTKAYLEH 1020 NRRVAEAAAL EDKHWAITIT DPRLNVCLEN HCDWNALLSY WDKTVNSSSS VLA* 1080 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd00505 | Glyco_transf_8 | 1.0e-13 | 760 | 968 | 247 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. | ||
cd06914 | GT8_GNT1 | 3.0e-17 | 758 | 912 | 167 | + GNT1 is a fungal enzyme that belongs to the GT 8 family. N-acetylglucosaminyltransferase is a fungal enzyme that catalyzes the addition of N-acetyl-D-glucosamine to mannotetraose side chains by an alpha 1-2 linkage during the synthesis of mannan. The N-acetyl-D-glucosamine moiety in mannan plays a role in the attachment of mannan to asparagine residues in proteins. The mannotetraose and its N-acetyl-D-glucosamine derivative side chains of mannan are the principle immunochemical determinants on the cell surface. N-acetylglucosaminyltransferase is a member of glycosyltransferase family 8, which are, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed, retaining glycosyltransferases. | ||
PLN00176 | PLN00176 | 2.0e-17 | 748 | 968 | 268 | + galactinol synthase | ||
pfam01501 | Glyco_transf_8 | 2.0e-34 | 760 | 970 | 254 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. | ||
cd02537 | GT8_Glycogenin | 9.0e-65 | 757 | 1000 | 254 | + Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen. Glycogenin initiates the biosynthesis of glycogen by incorporating glucose residues through a self-glucosylation reaction at a Tyr residue, and then acts as substrate for chain elongation by glycogen synthase and branching enzyme. It contains a conserved DxD motif and an N-terminal beta-alpha-beta Rossmann-like fold that are common to the nucleotide-binding domains of most glycosyltransferases. The DxD motif is essential for coordination of the catalytic divalent cation, most commonly Mn2+. Glycogenin can be classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. It is placed in glycosyltransferase family 8 which includes lipopolysaccharide glucose and galactose transferases and galactinol synthases. |
Gene Ontology | |
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GO Term | Description |
GO:0016757 | transferase activity, transferring glycosyl groups |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAS90653.1 | 0 | 571 | 1061 | 163 | 653 | putative glycogenin [Oryza sativa Japonica Group] |
GenBank | EEC79261.1 | 0 | 567 | 1061 | 159 | 653 | hypothetical protein OsI_20036 [Oryza sativa Indica Group] |
RefSeq | XP_001756144.1 | 0 | 576 | 1063 | 57 | 546 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001777541.1 | 0 | 543 | 1073 | 1 | 532 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001783069.1 | 0 | 528 | 1073 | 1 | 542 | predicted protein [Physcomitrella patens subsp. patens] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3u2t_A | 9e-16 | 745 | 973 | 9 | 247 | A Chain A, Crystal Structure Of Human Glycogenin-1 (Gyg1) Complexed With Manganese |
PDB | 1zdg_A | 0.000000000000003 | 751 | 973 | 18 | 245 | A Chain A, Crystal Structure Of Human Glycogenin-1 (Gyg1) Complexed With Manganese |
PDB | 1zcy_A | 0.000000000000003 | 751 | 973 | 18 | 245 | A Chain A, Apo Form Of A Mutant Of Glycogenin In Which Asp159 Is Replaced By Ser |
PDB | 3usq_A | 0.000000000000003 | 751 | 968 | 18 | 240 | A Chain A, Structure Of D159sY194F GLYCOGENIN MUTANT TRUNCATED AT RESIDUE 270 |
PDB | 1zcv_A | 0.000000000000005 | 751 | 973 | 18 | 245 | A Chain A, Apo Form Of A Mutant Of Glycogenin In Which Asp159 Is Replaced By Asn |