Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s372_55V6.1 |
Family | GT2 |
Protein Properties | Length: 672 Molecular Weight: 75800.8 Isoelectric Point: 6.5618 |
Chromosome | Chromosome/Scaffold: 372 Start: 202031 End: 204046 |
Description | cellulose synthase-like D6 |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT2 | 154 | 325 | 4.3e-27 |
IFIPCCKEPTEVPIESVKAALALDYPVDLVKVFVLDDGGDDDLRAFCDAIKVETAGRVVYIRREKKEGVPHNFKCGNMNNGLKYSNAEYVVMMDADMILH PSYLRRLLPHIVSSSDVSFVQIPQAFYNLPIGDPLNDCSSLGYDRILPSRDTLGTAACVGTGAMFRRKYLDH |
Full Sequence |
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Protein Sequence Length: 672 Download |
MAPPSAMDWA KAVVYKPIEI DDDVEIALSN RSNTLNCNEK IDPLLCDEPD EDEKPRRHLS 60 IRNYQKLKHY CLCSILVISS IIAQFDYVAY KFSIYSSHPG ETMLRPWLIV LMFCECLYFI 120 TTLLSAVDHL IPPSNRPDLG LLNTSLANTP TVDIFIPCCK EPTEVPIESV KAALALDYPV 180 DLVKVFVLDD GGDDDLRAFC DAIKVETAGR VVYIRREKKE GVPHNFKCGN MNNGLKYSNA 240 EYVVMMDADM ILHPSYLRRL LPHIVSSSDV SFVQIPQAFY NLPIGDPLND CSSLGYDRIL 300 PSRDTLGTAA CVGTGAMFRR KYLDHIGGFQ PQSITEDTMT AFTLWNRGYE SVYIDEKLQI 360 GLTPWTFEGY IKQRTRWGKG AIQQFSASAR ACLGRESQLN FIQKILYFYH TGYYFVSFVN 420 VLLMGTLLCA LAFNWNLSVG TAAENATLVK HLAIYLLMFR VTWFALWLNM PQGLMMRNRE 480 ESHFWWITPY FLEMCIESLV DFKSTYDFVP TSNIDKNAAA AQTSQSGPVS SWLTKYKNQV 540 GQVKYHLAFV ITSMAVVLYR ASGAFFTGNC SEIFLVVGLS VFFVSVGAHM MIPVIYVFFP 600 PSFKPSQRKS LLRYNADGVP QFTPEDGIPK WSSGVIPYEI LTWISLVFWL AALVFVIVDP 660 LGATLQSRCK A* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd06435 | CESA_NdvC_like | 2.0e-31 | 154 | 385 | 241 | + NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase. NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase. Bradyrhizobium japonicum synthesizes periplasmic cyclic beta-(1,3),beta-(1,6)-D-glucans during growth under hypoosmotic conditions. Two genes (ndvB, ndvC) are involved in the beta-(1, 3), beta-(1,6)-glucan synthesis. The ndvC mutant strain resulted in synthesis of altered cyclic beta-glucans composed almost entirely of beta-(1, 3)-glycosyl linkages. The periplasmic cyclic beta-(1,3),beta-(1,6)-D-glucans function for osmoregulation. The ndvC mutation also affects the ability of the bacteria to establish a successful symbiotic interaction with host plant. Thus, the beta-glucans may function as suppressors of a host defense response. | ||
pfam13641 | Glyco_tranf_2_3 | 3.0e-33 | 150 | 380 | 235 | + Glycosyltransferase like family 2. Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis. | ||
COG1215 | COG1215 | 6.0e-38 | 107 | 492 | 397 | + Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane] | ||
TIGR03030 | CelA | 4.0e-47 | 109 | 459 | 371 | + cellulose synthase catalytic subunit (UDP-forming). Cellulose synthase catalyzes the beta-1,4 polymerization of glucose residues in the formation of cellulose. In bacteria, the substrate is UDP-glucose. The synthase consists of two subunits (or domains in the frequent cases where it is encoded as a single polypeptide), the catalytic domain modelled here and the regulatory domain (pfam03170). The regulatory domain binds the allosteric activator cyclic di-GMP. The protein is membrane-associated and probably assembles into multimers such that the individual cellulose strands can self-assemble into multi-strand fibrils. | ||
cd06421 | CESA_CelA_like | 3.0e-76 | 150 | 385 | 240 | + CESA_CelA_like are involved in the elongation of the glucan chain of cellulose. Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
GO:0016760 | cellulose synthase (UDP-forming) activity |
GO:0030244 | cellulose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_001259116.1 | 0 | 135 | 623 | 204 | 702 | glycosyl transferase, putative [Neosartorya fischeri NRRL 181] |
RefSeq | XP_001557767.1 | 0 | 131 | 500 | 174 | 545 | hypothetical protein BC1G_03864 [Botryotinia fuckeliana B05.10] |
RefSeq | XP_001783660.1 | 0 | 1 | 633 | 1 | 633 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_002563258.1 | 0 | 150 | 656 | 231 | 748 | Pc20g07350 [Penicillium chrysogenum Wisconsin 54-1255] |
RefSeq | YP_002540629.1 | 0 | 110 | 408 | 77 | 368 | Curdlan Synthase [Agrobacterium radiobacter K84] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 4hg6_A | 2e-37 | 110 | 458 | 107 | 462 | B Chain B, Structure Of A Cellulose Synthase - Cellulose Translocation Intermediate |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
cellulose biosynthesis | CELLULOSE-SYNTHASE-UDP-FORMING-RXN | EC-2.4.1.12 | cellulose synthase (UDP-forming) |