| Basic Information | |
|---|---|
| Species | Physcomitrella patens |
| Cazyme ID | Pp1s387_34V6.1 |
| Family | GH47 |
| Protein Properties | Length: 591 Molecular Weight: 67428 Isoelectric Point: 6.3419 |
| Chromosome | Chromosome/Scaffold: 387 Start: 209348 End: 214773 |
| Description | alpha-mannosidase 2 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GH47 | 123 | 554 | 0 |
| AMLHAWTCYEKYAWGFDELKPQSKTGVNQFAGLGATIVDSLDTLFIMGLQKQFIKARDWVAENLDFNKHVETSVFETTIRVLGGLLSAYDLSGEPMFLRK AQEIADRLMPAWESPSGIPYNIINLATGHASNPSWSGGQSILADLGTEQVELIALTQRTGVPHYKEKAEKVIKQLRKVFPNDGLLSYYVNPDSGQPSYGK VTFGAMGDSFYEYLLKVWILGNKTEVVKHYREMWDQSIDGMMKSLVQKTSNPPIYTYLAERSGNQLIHKMDELACFTPGMLVLGTDGASPQKAKEYLDLA EELANTCYNMYMSTHSKLAGESYNFNNGGMEVGVSWNILRPETIESLMYLWRKTGNKKYRDWGWNIFQAFEAQSRTSTGYVGLRNVHTGEKDDMMQSFFL AETLKYLYLLFSPSTVVPLDEWVFNTEAHPVR | |||
| Full Sequence |
|---|
| Protein Sequence Length: 591 Download |
| MAIQSRRSSV WPRYLNPTYY LRRPRRLLIL FAFFVCTTFF LWDRHNLVLH HEETVGKLAR 60 ENDKLQHSLK DLTKMLEEKG EVLPQELISQ EQEMSDTISS EEGLAGVDED PVAAERRNKI 120 KDAMLHAWTC YEKYAWGFDE LKPQSKTGVN QFAGLGATIV DSLDTLFIMG LQKQFIKARD 180 WVAENLDFNK HVETSVFETT IRVLGGLLSA YDLSGEPMFL RKAQEIADRL MPAWESPSGI 240 PYNIINLATG HASNPSWSGG QSILADLGTE QVELIALTQR TGVPHYKEKA EKVIKQLRKV 300 FPNDGLLSYY VNPDSGQPSY GKVTFGAMGD SFYEYLLKVW ILGNKTEVVK HYREMWDQSI 360 DGMMKSLVQK TSNPPIYTYL AERSGNQLIH KMDELACFTP GMLVLGTDGA SPQKAKEYLD 420 LAEELANTCY NMYMSTHSKL AGESYNFNNG GMEVGVSWNI LRPETIESLM YLWRKTGNKK 480 YRDWGWNIFQ AFEAQSRTST GYVGLRNVHT GEKDDMMQSF FLAETLKYLY LLFSPSTVVP 540 LDEWVFNTEA HPVRIKTRMN EPIALEDDLE KTKITNALLP LERRPGWKGK * 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG1331 | COG1331 | 0.004 | 202 | 297 | 96 | + Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones] | ||
| pfam01532 | Glyco_hydro_47 | 0 | 123 | 555 | 451 | + Glycosyl hydrolase family 47. Members of this family are alpha-mannosidases that catalyze the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2). | ||
| PTZ00470 | PTZ00470 | 0 | 113 | 555 | 455 | + glycoside hydrolase family 47 protein; Provisional | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity |
| GO:0005509 | calcium ion binding |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACN34773.1 | 0 | 13 | 555 | 14 | 541 | unknown [Zea mays] |
| EMBL | CBI18472.1 | 0 | 1 | 558 | 1 | 544 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_001755014.1 | 0 | 1 | 590 | 1 | 605 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001784033.1 | 0 | 1 | 590 | 1 | 563 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_002448484.1 | 0 | 13 | 555 | 14 | 540 | hypothetical protein SORBIDRAFT_06g027810 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1nxc_A | 0 | 110 | 555 | 14 | 465 | A Chain A, Structure Of Mouse Golgi Alpha-1,2-Mannosidase Ia Reveals The Molecular Basis For Substrate Specificity Among Class I Enzymes (Family 47 Glycosidases) |
| PDB | 1fmi_A | 0 | 109 | 557 | 2 | 458 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo3_A | 0 | 109 | 557 | 2 | 458 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo2_A | 0 | 109 | 557 | 2 | 458 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase In Complex With 1-Deoxymannojirimycin |
| PDB | 1x9d_A | 0 | 116 | 557 | 88 | 536 | A Chain A, Crystal Structure Of Human Class I Alpha-1,2-Mannosidase In Complex With Thio-Disaccharide Substrate Analogue |
