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Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s3_407V6.2 |
Family | GT47 |
Protein Properties | Length: 538 Molecular Weight: 61248.5 Isoelectric Point: 8.1517 |
Chromosome | Chromosome/Scaffold: 3 Start: 2316825 End: 2321129 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 123 | 470 | 0 |
CEGRHVYMYDPPTEFTVDIIKNCQNWSTWWTMCEDAQNGGFGVRLRLRKSDPLSSITQPPDSWYRTEQFTLDMSWHSRMKTYPCLTDDPNEASIFYVPFY HSPDLTRNLKNPNMTETDYLTTRFVKWLGKQAPYQRYGGRRHFIVMGRIFWDHNRLFNSTHGWGSSLFSQPELKNVFKVMIERSEWAADTIAIPYPTNFH PTSEAALQAWEAKIRVAKRTKLISFAASDRSRNMTGMVRGELFDQCSKSKTCNHVICSTELCVFRPQTIYKISLESVFCLEPGGDSPTRKGIFDSLITGC IPVLFNTNQAVKMYLWHLPGNGSDYSILIDENKVVNDHYDVMQHLERI |
Full Sequence |
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Protein Sequence Length: 538 Download |
MGYAPQWNTV ATKGNHRAST KSRLAVGRRA YVAIGAVLVF LLYTWIGYDE MRLGPRTSSR 60 FKQTLRSGGI AGQECEQSAE PSQEGIRSLG SYATNALESC ESAGPDLPVG YNFEATKLTP 120 EECEGRHVYM YDPPTEFTVD IIKNCQNWST WWTMCEDAQN GGFGVRLRLR KSDPLSSITQ 180 PPDSWYRTEQ FTLDMSWHSR MKTYPCLTDD PNEASIFYVP FYHSPDLTRN LKNPNMTETD 240 YLTTRFVKWL GKQAPYQRYG GRRHFIVMGR IFWDHNRLFN STHGWGSSLF SQPELKNVFK 300 VMIERSEWAA DTIAIPYPTN FHPTSEAALQ AWEAKIRVAK RTKLISFAAS DRSRNMTGMV 360 RGELFDQCSK SKTCNHVICS TELCVFRPQT IYKISLESVF CLEPGGDSPT RKGIFDSLIT 420 GCIPVLFNTN QAVKMYLWHL PGNGSDYSIL IDENKVVNDH YDVMQHLERI PKEEIARIQE 480 NIFAMFPRLL YRNTKLTGEY KTKDAFDITI DKLLQKLPAE DKTSGNHTTI APFNGTS* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-45 | 123 | 470 | 360 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_001752322.1 | 0 | 1 | 531 | 1 | 531 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001755886.1 | 0 | 121 | 514 | 1 | 394 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001757088.1 | 0 | 111 | 516 | 14 | 418 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001766126.1 | 0 | 123 | 513 | 1 | 378 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001785740.1 | 0 | 123 | 514 | 1 | 392 | predicted protein [Physcomitrella patens subsp. patens] |