Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s3_628V6.1 |
Family | AA3 |
Protein Properties | Length: 613 Molecular Weight: 66682.9 Isoelectric Point: 4.4887 |
Chromosome | Chromosome/Scaffold: 3 Start: 3866795 End: 3869535 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 57 | 605 | 0 |
NATEAPLLGRNYDYIIVGGGTAGCPLAATLSQNFSVLLLERGGQPYQNDLVENLVGFYPNLQLDTSTSASQSFTSEDGVPNQRARVLGGGSAVNAGFFTF ADPQFVAEMNWDVILVNESFTWVADEVAQIPTIQVFQSAARDALLEAGVTPFNGETYDHLIGTKVGGSLFDSNDRRHTAADLLTYANPDNLDVYIWASAQ RLVFATGVGPNGDRQPRAIGVEYTDLEGYSHTVLLNDNPGSEVILTAGALGSPVLLMLSGIGPADHLADFNIAAILDNPAVGSRMADNPTNSMWVLTNQE VEVTLIQVVGITSWGSYIEISSGQSEALIGAFESTPLSTTSSRSNKLNNSTVTATSLQDTITAAIREVPEQFRYQAVWGGTILQKIWGPLSRGLLRLSSL NAVDNPRVWFNYFQEQVDLAICEQGIRAVLDTLASPSLARLQYTNDTIPFILQPVNDAVVGARPQRDLSNSTQDTINIRQWCMDSVMTIWHYHGGCVVDD VVRRDYRVIGTQSLRVIDGSTFARSPGANPQATVMMLGRYMGVQILRER |
Full Sequence |
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Protein Sequence Length: 613 Download |
MGDNDYRERQ GSDHSNDFKS SKAKWKFVCV LIVLQTRLLY TCAAKIYSDP NYSFVLNATE 60 APLLGRNYDY IIVGGGTAGC PLAATLSQNF SVLLLERGGQ PYQNDLVENL VGFYPNLQLD 120 TSTSASQSFT SEDGVPNQRA RVLGGGSAVN AGFFTFADPQ FVAEMNWDVI LVNESFTWVA 180 DEVAQIPTIQ VFQSAARDAL LEAGVTPFNG ETYDHLIGTK VGGSLFDSND RRHTAADLLT 240 YANPDNLDVY IWASAQRLVF ATGVGPNGDR QPRAIGVEYT DLEGYSHTVL LNDNPGSEVI 300 LTAGALGSPV LLMLSGIGPA DHLADFNIAA ILDNPAVGSR MADNPTNSMW VLTNQEVEVT 360 LIQVVGITSW GSYIEISSGQ SEALIGAFES TPLSTTSSRS NKLNNSTVTA TSLQDTITAA 420 IREVPEQFRY QAVWGGTILQ KIWGPLSRGL LRLSSLNAVD NPRVWFNYFQ EQVDLAICEQ 480 GIRAVLDTLA SPSLARLQYT NDTIPFILQP VNDAVVGARP QRDLSNSTQD TINIRQWCMD 540 SVMTIWHYHG GCVVDDVVRR DYRVIGTQSL RVIDGSTFAR SPGANPQATV MMLGRYMGVQ 600 ILRERLGSEA GV* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
TIGR01810 | betA | 1.0e-19 | 69 | 344 | 308 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
TIGR03970 | Rv0697 | 8.0e-22 | 69 | 352 | 318 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
COG2303 | BetA | 2.0e-36 | 65 | 605 | 592 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PLN02785 | PLN02785 | 0 | 26 | 612 | 605 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI34759.1 | 0 | 50 | 609 | 30 | 575 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_001752366.1 | 0 | 68 | 612 | 1 | 545 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001766599.1 | 0 | 68 | 612 | 1 | 551 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_002298074.1 | 0 | 50 | 609 | 29 | 573 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002510860.1 | 0 | 25 | 606 | 6 | 571 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3gdp_B | 0 | 53 | 609 | 13 | 521 | A Chain A, Pectin Methylesterase From Yersinia Enterocolitica |
PDB | 3gdp_A | 0 | 53 | 609 | 13 | 521 | A Chain A, Pectin Methylesterase From Yersinia Enterocolitica |
PDB | 3gdn_B | 0 | 53 | 609 | 13 | 521 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 3gdn_A | 0 | 53 | 609 | 13 | 521 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 1ju2_B | 0 | 53 | 609 | 13 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
cutin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |
cutin biosynthesis | RXN-9802 | EC-1.1.1 | 16-hydroxypalmitate dehydrogenase |
suberin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
DC936915 | 220 | 1 | 220 | 0 |
DC932837 | 221 | 1 | 221 | 0 |
HO796743 | 548 | 69 | 613 | 0 |
DC929855 | 217 | 1 | 217 | 0 |
DC935706 | 217 | 1 | 217 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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