Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s45_211V6.1 |
Family | GT47 |
Protein Properties | Length: 515 Molecular Weight: 58870.5 Isoelectric Point: 6.8625 |
Chromosome | Chromosome/Scaffold: 45 Start: 1566427 End: 1568339 |
Description | exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 124 | 446 | 0 |
AELKVYMYDLSSEFHYGLIPGYEVEKGQYWPRNGSEIPEYPGGLYQQHSPEHWLTSDLLTSNMADRNTACTAFRVADWRDADVIFVPFFASLSYNRFGKA SEEKRLTDLIKDQNDVLQLKLVKFLEEQPAWKASGGRDHVFVIHHPNSMQATRNRLRNSLFIVSDFGRYDSEVANIQKDVVAPYKHVIPTFDFDDSSFHT RKILLFFQGAIVRKEGGKIRHELYRLLKDKPGVRFTTGNTALDGFQSATIGMRSSKFCLNMAGDTPSSNRLFDSIVSHCVPVIISDDIELPFEDTLDYSN FCIFINSSLALKPGYVINMLRNV |
Full Sequence |
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Protein Sequence Length: 515 Download |
MWKRSKSANR PSQCCKDHGI RKSCFLLAIT LFVICAVSGF SFYRHHSGRE TEGSRKISTV 60 SYFPYLRLNK QSLETNVAGE ETPLTGSELD EASESDVASF LESFDVGSQG DSEDEVQGCN 120 YWQAELKVYM YDLSSEFHYG LIPGYEVEKG QYWPRNGSEI PEYPGGLYQQ HSPEHWLTSD 180 LLTSNMADRN TACTAFRVAD WRDADVIFVP FFASLSYNRF GKASEEKRLT DLIKDQNDVL 240 QLKLVKFLEE QPAWKASGGR DHVFVIHHPN SMQATRNRLR NSLFIVSDFG RYDSEVANIQ 300 KDVVAPYKHV IPTFDFDDSS FHTRKILLFF QGAIVRKEGG KIRHELYRLL KDKPGVRFTT 360 GNTALDGFQS ATIGMRSSKF CLNMAGDTPS SNRLFDSIVS HCVPVIISDD IELPFEDTLD 420 YSNFCIFINS SLALKPGYVI NMLRNVSEEE WTQLWNQLLL VEHHFEYQHP TRKNDAVNMV 480 WKDIARKLPA INLAINRQRR YVPKPPGFPY HKLP* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-54 | 126 | 446 | 331 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_001758016.1 | 0 | 119 | 501 | 92 | 475 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001759885.1 | 0 | 126 | 501 | 1 | 383 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001760871.1 | 0 | 130 | 500 | 1 | 371 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001761432.1 | 0 | 126 | 501 | 1 | 377 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001773896.1 | 0 | 130 | 501 | 1 | 369 | predicted protein [Physcomitrella patens subsp. patens] |