Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s472_10V6.1 |
Family | AA3 |
Protein Properties | Length: 479 Molecular Weight: 52611.7 Isoelectric Point: 8.9851 |
Chromosome | Chromosome/Scaffold: 472 Start: 81650 End: 83249 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 14 | 469 | 0 |
TEPLHAQYQYIAVGGGTARCALATTLSEQYKVLLLERGGTPYGNPRIERGSAVNAGFYSRASAAQVRAAGWKPSRVAEAYRWVEKKIVHPGSHGVWQTAL QDSLLQTGVTPNNGLNNDHIYGTKVGGSLFDKQGRRDSAADFLSYANDKLLTVLTFANVQRIIFDNSGKIYHVEIIYSKTQPGALGSPQLLLLSGIGSCE HLAEFNITCHVELNAVGADMVDNPKNAIVVLSPTPVETSLLSVVGIDKEFIIEGGSGSNFSWQLPGMGQLNYVAPSQRTPDFVASAFILTKLYDPISYGS LRLNSTDINRNPYVKFNYYSHPRDIEYCISGVKRFYKLLRAPAFQPFRFTTVTSLVASIYYQLKEGESTEGAYLPDVSNYTETAEWCRTTLTTIWHFHGG CTVGKVVDKSYRVFGTRPLRVVDGSTFTKSPGTNPQATVMMLGRYVGVKILKERRI |
Full Sequence |
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Protein Sequence Length: 479 Download |
MCSAEFFDVR DATTEPLHAQ YQYIAVGGGT ARCALATTLS EQYKVLLLER GGTPYGNPRI 60 ERGSAVNAGF YSRASAAQVR AAGWKPSRVA EAYRWVEKKI VHPGSHGVWQ TALQDSLLQT 120 GVTPNNGLNN DHIYGTKVGG SLFDKQGRRD SAADFLSYAN DKLLTVLTFA NVQRIIFDNS 180 GKIYHVEIIY SKTQPGALGS PQLLLLSGIG SCEHLAEFNI TCHVELNAVG ADMVDNPKNA 240 IVVLSPTPVE TSLLSVVGID KEFIIEGGSG SNFSWQLPGM GQLNYVAPSQ RTPDFVASAF 300 ILTKLYDPIS YGSLRLNSTD INRNPYVKFN YYSHPRDIEY CISGVKRFYK LLRAPAFQPF 360 RFTTVTSLVA SIYYQLKEGE STEGAYLPDV SNYTETAEWC RTTLTTIWHF HGGCTVGKVV 420 DKSYRVFGTR PLRVVDGSTF TKSPGTNPQA TVMMLGRYVG VKILKERRIT PKAANTTN* 480 |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
TIGR03970 | Rv0697 | 1.0e-23 | 26 | 456 | 522 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. |
pfam05199 | GMC_oxred_C | 7.0e-26 | 308 | 456 | 154 | + GMC oxidoreductase. This domain found associated with pfam00732. |
TIGR01810 | betA | 5.0e-28 | 23 | 456 | 546 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. |
COG2303 | BetA | 2.0e-38 | 18 | 468 | 560 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] |
PLN02785 | PLN02785 | 2.0e-150 | 18 | 467 | 542 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI34759.1 | 0 | 1 | 467 | 23 | 571 | unnamed protein product [Vitis vinifera] |
GenBank | EAY87068.1 | 0 | 9 | 470 | 31 | 576 | hypothetical protein OsI_08464 [Oryza sativa Indica Group] |
GenBank | EEE57571.1 | 0 | 9 | 470 | 31 | 563 | hypothetical protein OsJ_07923 [Oryza sativa Japonica Group] |
RefSeq | XP_002282510.1 | 0 | 9 | 467 | 1 | 537 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002298074.1 | 0 | 11 | 475 | 36 | 577 | predicted protein [Populus trichocarpa] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1ju2_B | 0 | 11 | 467 | 17 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 1ju2_A | 0 | 11 | 467 | 17 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 3gdp_B | 0 | 11 | 467 | 17 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 3gdp_A | 0 | 11 | 467 | 17 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 3gdn_B | 0 | 11 | 467 | 17 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
cutin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |
cutin biosynthesis | RXN-9802 | EC-1.1.1 | 16-hydroxypalmitate dehydrogenase |
suberin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO796743 | 531 | 23 | 467 | 0 |
HO799688 | 306 | 196 | 476 | 0 |
EX529929 | 305 | 187 | 467 | 0 |
CX666126 | 283 | 187 | 467 | 0 |
HO852522 | 381 | 137 | 471 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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