Basic Information | |
---|---|
Species | Physcomitrella patens |
Cazyme ID | Pp1s47_268V6.1 |
Family | GT47 |
Protein Properties | Length: 560 Molecular Weight: 64284.9 Isoelectric Point: 6.5998 |
Chromosome | Chromosome/Scaffold: 47 Start: 1718339 End: 1720694 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 154 | 489 | 0 |
CDGRRVYMYDLPSTMNTDILKNCSGNLVKWLNFCPHHKNHGFGAVVNATVEVFRQDWYGTDAYMLEVIFYERMQTYSCRTSDPAEADLFFIPYFAGLDAL PYLYTDSKRELQQGREVVEWLEENAPKTWRRHGGHDHFYIAGRTAWDFCRPLTKVNWWGTSLFNNPEMENTTAMVLERRPWRDDEVAIPYPVGFHPSTSA TLHSWIEVVRSSPRKHLFSFSGALRPHLTISIREILSRQCSEAGNACSRLDCGKIKCSHEPEPIYTSLLQATFCLQPRGDTSTRRSVIDSIVSGCIPVFF HEDTAYTQYHWFLPKDYENFSVFIDEKDMKDGNADV |
Full Sequence |
---|
Protein Sequence Length: 560 Download |
MFARKFSKQY HLRKPRAKYI YVCCSLSFLL ILITGWSRPL PTTPTSAASM AVEESIQPEP 60 KFLSVSKETL LAESQPLQSE LAEAEGEHLE EPGSDAVRSE KLEAKQEREA RRSEHMQMER 120 EREAQQSKHV EVYQEQKVEP ESLVKNVRAL ENPCDGRRVY MYDLPSTMNT DILKNCSGNL 180 VKWLNFCPHH KNHGFGAVVN ATVEVFRQDW YGTDAYMLEV IFYERMQTYS CRTSDPAEAD 240 LFFIPYFAGL DALPYLYTDS KRELQQGREV VEWLEENAPK TWRRHGGHDH FYIAGRTAWD 300 FCRPLTKVNW WGTSLFNNPE MENTTAMVLE RRPWRDDEVA IPYPVGFHPS TSATLHSWIE 360 VVRSSPRKHL FSFSGALRPH LTISIREILS RQCSEAGNAC SRLDCGKIKC SHEPEPIYTS 420 LLQATFCLQP RGDTSTRRSV IDSIVSGCIP VFFHEDTAYT QYHWFLPKDY ENFSVFIDEK 480 DMKDGNADVS KILGAYTAKQ VEQIRERLIK IIPNVLYRHP ESTDLAESMR DAFDLTLEGM 540 ARKVAQFKLS TGRGIATLS* |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-55 | 153 | 482 | 348 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_001752641.1 | 0 | 154 | 550 | 7 | 403 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001752721.1 | 0 | 144 | 556 | 90 | 496 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001761213.1 | 0 | 118 | 559 | 1 | 442 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001763405.1 | 0 | 152 | 543 | 1 | 386 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001773063.1 | 0 | 154 | 548 | 1 | 395 | predicted protein [Physcomitrella patens subsp. patens] |