Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s48_110V6.1 |
Family | GT47 |
Protein Properties | Length: 543 Molecular Weight: 61477.9 Isoelectric Point: 6.8501 |
Chromosome | Chromosome/Scaffold: 48 Start: 1028819 End: 1032644 |
Description | exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 158 | 481 | 0 |
ATLKLFMYDLPPEFHYGMLVAQTDSRKQTWPKNVTDIPPYLGGLYKQHSPEYWLTTDLLTSNMAGRQSACTAFRVSDWKAADYMFVPFFASVAYNKYTKT EHHAGGELDLVGDKNQKLQEKLLEYLKQQPAWQASDGCDHILVMHHPNSMHAMRDSFRNVLFVLADFGRYPPDVANVEKDVVAPYKHIIPSFDNDSSSFE DRETLLFFQGTIVRKQGGVIRQQLYEMLKDEEGVHFEEGSSGSEGVHSATSGMRGSKFCLNIAGDTPSSNRLFDSIASHCVPVIISDDIELPFEDELDYS EFCVFIKSEDALKEKYVINLLRSI |
Full Sequence |
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Protein Sequence Length: 543 Download |
MATVGEQTFR TEKMMKRGLL PSNVLEHQNC GPNCISFPAC SVEAKSTCQP RFRLLRGYEE 60 WAARNHILAI FSLLAIFALS CTFMFADSMR RSTEIIEEID THSLPKLSLP DQNSWATENS 120 LKRSGLLSEE VGGSDSDGVA HPVGGDGKVP FGCNDKSATL KLFMYDLPPE FHYGMLVAQT 180 DSRKQTWPKN VTDIPPYLGG LYKQHSPEYW LTTDLLTSNM AGRQSACTAF RVSDWKAADY 240 MFVPFFASVA YNKYTKTEHH AGGELDLVGD KNQKLQEKLL EYLKQQPAWQ ASDGCDHILV 300 MHHPNSMHAM RDSFRNVLFV LADFGRYPPD VANVEKDVVA PYKHIIPSFD NDSSSFEDRE 360 TLLFFQGTIV RKQGGVIRQQ LYEMLKDEEG VHFEEGSSGS EGVHSATSGM RGSKFCLNIA 420 GDTPSSNRLF DSIASHCVPV IISDDIELPF EDELDYSEFC VFIKSEDALK EKYVINLLRS 480 ITRVQWTFLW KRLKAVARHF EYQHPTKPYD AVNMVWRAIA RRAPSVKLLL HKKRHFLRSL 540 QN* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-43 | 160 | 481 | 332 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_001758016.1 | 0 | 84 | 542 | 1 | 481 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001759885.1 | 0 | 160 | 536 | 1 | 383 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001760871.1 | 0 | 164 | 534 | 1 | 370 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001761432.1 | 0 | 160 | 536 | 1 | 377 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001773896.1 | 0 | 164 | 536 | 1 | 369 | predicted protein [Physcomitrella patens subsp. patens] |