Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s49_46V6.1 |
Family | GT2 |
Protein Properties | Length: 423 Molecular Weight: 46429.8 Isoelectric Point: 9.2512 |
Chromosome | Chromosome/Scaffold: 49 Start: 316290 End: 319047 |
Description | Nucleotide-diphospho-sugar transferases superfamily protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT2 | 86 | 256 | 6.4e-24 |
SVIIPVYNEIAAIGTLVEKVGDVMQKRGGPYEVVCVDDGSTDGTARILKQMAAEREDMRVVIFRRNFGQTAAMAAGFDFAAGDVFVTMDGDLQNDAEDIP KLVDQLVYGNQGGHPVNTGVVREDGGYDLVCGWRRKRKDNAFTRNFPSWVANMLIGALTGVRLHDYGCSLK |
Full Sequence |
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Protein Sequence Length: 423 Download |
MLLSGPTLVG RYTFVKLQPW AKSRGCVADE VLLQLPSFKK RRMQALSLKT TPSRKGVTQA 60 VLEFASGPVS EESEPREEDK NSPAVSVIIP VYNEIAAIGT LVEKVGDVMQ KRGGPYEVVC 120 VDDGSTDGTA RILKQMAAER EDMRVVIFRR NFGQTAAMAA GFDFAAGDVF VTMDGDLQND 180 AEDIPKLVDQ LVYGNQGGHP VNTGVVREDG GYDLVCGWRR KRKDNAFTRN FPSWVANMLI 240 GALTGVRLHD YGCSLKAYRA PLLSTLLLYG EMHRFIPTLA AMEGAAISEL EVRHHPRTLG 300 KSKYGLGRIF RVLMDLTTVY FLQRFRQKPM HFIGFLGGVC MLGSIVAAAS TSRSLVKTAH 360 VWGYSMAISS ASPGFVLSLQ LLIMGLQLVC LGLVAEVCVR IYYESQSQPV YRVREVATST 420 TR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd04188 | DPG_synthase | 3.0e-22 | 87 | 267 | 188 | + DPG_synthase is involved in protein N-linked glycosylation. UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. | ||
cd06442 | DPM1_like | 1.0e-29 | 87 | 313 | 241 | + DPM1_like represents putative enzymes similar to eukaryotic DPM1. Proteins similar to eukaryotic DPM1, including enzymes from bacteria and archaea; DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. This protein family belongs to Glycosyltransferase 2 superfamily. | ||
PRK10714 | PRK10714 | 2.0e-41 | 85 | 318 | 236 | + undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional | ||
cd04179 | DPM_DPG-synthase_like | 4.0e-53 | 87 | 285 | 202 | + DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily. DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. The UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. This protein family belongs to Glycosyltransferase 2 superfamily. | ||
cd04187 | DPM1_like_bac | 2.0e-60 | 87 | 284 | 198 | + Bacterial DPM1_like enzymes are related to eukaryotic DPM1. A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily. |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAO90603.1 | 0 | 68 | 416 | 6 | 329 | unnamed protein product [Microcystis aeruginosa PCC 7806] |
RefSeq | NP_898206.1 | 0 | 85 | 415 | 7 | 312 | glycosyl transferase family protein [Synechococcus sp. WH 8102] |
RefSeq | XP_001761573.1 | 0 | 1 | 422 | 107 | 559 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | YP_001655916.1 | 0 | 84 | 416 | 21 | 329 | glycosyl transferase [Microcystis aeruginosa NIES-843] |
RefSeq | YP_002375402.1 | 0 | 83 | 421 | 22 | 336 | glycosyl transferase family 2 [Cyanothece sp. PCC 7424] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3bcv_B | 0.00001 | 83 | 182 | 5 | 100 | A Chain A, Crystal Structure Of A Putative Glycosyltransferase From Bacteroides Fragilis |
PDB | 3bcv_A | 0.00001 | 83 | 182 | 5 | 100 | A Chain A, Crystal Structure Of A Putative Glycosyltransferase From Bacteroides Fragilis |
PDB | 2z86_D | 0.004 | 80 | 181 | 372 | 471 | A Chain A, Crystal Structure Of Chondroitin Polymerase From Escherichia Coli Strain K4 (K4cp) Complexed With Udp-Glcua And Udp |
PDB | 2z86_C | 0.004 | 80 | 181 | 372 | 471 | A Chain A, Crystal Structure Of Chondroitin Polymerase From Escherichia Coli Strain K4 (K4cp) Complexed With Udp-Glcua And Udp |
PDB | 2z86_B | 0.004 | 80 | 181 | 372 | 471 | A Chain A, Crystal Structure Of Chondroitin Polymerase From Escherichia Coli Strain K4 (K4cp) Complexed With Udp-Glcua And Udp |