| Basic Information | |
|---|---|
| Species | Physcomitrella patens |
| Cazyme ID | Pp1s55_131V6.1 |
| Family | GH29 |
| Protein Properties | Length: 499 Molecular Weight: 55750.9 Isoelectric Point: 4.8653 |
| Chromosome | Chromosome/Scaffold: 55 Start: 851066 End: 854044 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH29 | 48 | 344 | 0 |
| QLRFQRQEQIMFFHFGVNTFTGKEQGDGTEDPSIFNPEGLDARQWVREAKNAGFKVVILTAKHADGFCLWPSAYTNYSVKSSPWKNGTGDVVREVSDAAR EEGLEFGLYMSPWDRHEPTYGDTLLYNDYYLGQLRELLTMYGPISQFFVDGNKDPSSKDMYYLFDAWFALIHQMQPNANIFSDDGPDVRWVGNEAGEAGT TSWSMMNRSMVTIGGPFEEYLNEGDPNGSDWVPPECDVSIRPGWFWKESQQPKTVNKLLDIYYKSVGRNCVMLLNAPPNQTGLLHGTDVANLRDFRS | |||
| Full Sequence |
|---|
| Protein Sequence Length: 499 Download |
| MERDSLSLCG RSGLLALLLM SATAVVVVSF TSPLPPPLPI MPLPSYRQLR FQRQEQIMFF 60 HFGVNTFTGK EQGDGTEDPS IFNPEGLDAR QWVREAKNAG FKVVILTAKH ADGFCLWPSA 120 YTNYSVKSSP WKNGTGDVVR EVSDAAREEG LEFGLYMSPW DRHEPTYGDT LLYNDYYLGQ 180 LRELLTMYGP ISQFFVDGNK DPSSKDMYYL FDAWFALIHQ MQPNANIFSD DGPDVRWVGN 240 EAGEAGTTSW SMMNRSMVTI GGPFEEYLNE GDPNGSDWVP PECDVSIRPG WFWKESQQPK 300 TVNKLLDIYY KSVGRNCVML LNAPPNQTGL LHGTDVANLR DFRSVIDRIF ATNLASKARV 360 SASSTRGGDI SSFRPDQVLN DDLEAYWASE EGLTTPFLTL DLGSNKTFNV VKLQEAVHLG 420 QRVQLYHVDV MQDGRWKTVS VGTTIGYKKL DRFEKVHSQL VRIYIDGARG TPLISAVGLY 480 LDTWSALSLA AESTQVSE* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam00754 | F5_F8_type_C | 1.0e-6 | 360 | 471 | 119 | + F5/8 type C domain. This domain is also known as the discoidin (DS) domain family. | ||
| pfam01120 | Alpha_L_fucos | 3.0e-28 | 82 | 342 | 276 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 4.0e-29 | 82 | 342 | 280 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| COG3669 | COG3669 | 8.0e-70 | 48 | 480 | 454 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| GO:0007155 | cell adhesion |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAH68057.1 | 0 | 45 | 485 | 41 | 481 | B0103C08-B0602B01.14 [Oryza sativa (indica cultivar-group)] |
| RefSeq | NP_180377.2 | 0 | 35 | 488 | 29 | 485 | ATFUC1 (alpha-L-fucosidase 1); alpha-L-fucosidase [Arabidopsis thaliana] |
| Swiss-Prot | Q8GW72 | 0 | 35 | 488 | 29 | 485 | FUCO1_ARATH RecName: Full=Alpha-L-fucosidase 1; AltName: Full=Alpha-L-fucoside fucohydrolase; AltName: Full=Alpha-1,3/4-fucosidase; Short=AtFUC1; Flags: Precursor |
| RefSeq | XP_001762481.1 | 0 | 41 | 498 | 1 | 458 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_002313533.1 | 0 | 48 | 485 | 18 | 457 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3eyp_B | 0 | 39 | 480 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3eyp_A | 0 | 39 | 480 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3mo4_B | 0 | 44 | 475 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3mo4_A | 0 | 44 | 475 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3ues_B | 0 | 44 | 475 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
