| Basic Information | |
|---|---|
| Species | Physcomitrella patens |
| Cazyme ID | Pp1s5_330V6.1 |
| Family | GH31 |
| Protein Properties | Length: 1090 Molecular Weight: 121129 Isoelectric Point: 6.4582 |
| Chromosome | Chromosome/Scaffold: 5 Start: 2296756 End: 2303784 |
| Description | heteroglycan glucosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH31 | 300 | 711 | 0 |
| PTPEALMTSLSHAIGTMQLPPMWALGYQQCRWSYETAARVAEVATTFREKKIPCDVLWMDIDYMQGFRCFTFDKDAFPDPKGLSDELHSKGFKGVWMLDP GIMADKGYKAYDLGCEADVWIQTADGKPYVGECWPGPVVFPDFLNKRTREWWAKLVKDFVPVGVDGIWNDMNEPAVFKTVSKTMPETNIHRGDEEVGGRQ DHSHYHNVYGMFQARSTYEGMLLANENKRPFVLTRAAFIGSHRYAATWTGDNLANWEHLWMSIPMTLNLGLSGQPFSGPDIGGFAGDSTPKLFARWMGLG AMLPFARGHSEQGTIDQEPWSFGPEVEDLSRFALNRRYRLLPHFYTLFYKAHTTGVPVMTPVFFADPTDPKLRKVDDSFLLGSLLVKTWPTPKNRDSNAA FELPKGIWQRFH | |||
| Full Sequence |
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| Protein Sequence Length: 1090 Download |
| MFQILLCCLH QLPPSAAGAL HLHPSLLPFS PSFPLNASAL CFSSPSRPLS HLCWTRRRSC 60 NLSVSGHDQL ASGVAACCGR SGFWSRRSFL SANPVFSSVI GSGKYSKFQH IRPPRLSALR 120 AVSTDAQDTS SRRIAPASMI PACLSIIEKS VFRFDESELA RKEAAPSVSC LNPCLREEEI 180 KVESNEPEFI PAFDSDGANQ IVTLQLPSGT TFYGTGEVGG SVERTGKRIY SWNTDAWGYN 240 QNTTSLYQSH PWVFSVLPNG QAFGVLADTT RRCEIDLRKE AVIKIMAAAP FPVITFGPFP 300 TPEALMTSLS HAIGTMQLPP MWALGYQQCR WSYETAARVA EVATTFREKK IPCDVLWMDI 360 DYMQGFRCFT FDKDAFPDPK GLSDELHSKG FKGVWMLDPG IMADKGYKAY DLGCEADVWI 420 QTADGKPYVG ECWPGPVVFP DFLNKRTREW WAKLVKDFVP VGVDGIWNDM NEPAVFKTVS 480 KTMPETNIHR GDEEVGGRQD HSHYHNVYGM FQARSTYEGM LLANENKRPF VLTRAAFIGS 540 HRYAATWTGD NLANWEHLWM SIPMTLNLGL SGQPFSGPDI GGFAGDSTPK LFARWMGLGA 600 MLPFARGHSE QGTIDQEPWS FGPEVEDLSR FALNRRYRLL PHFYTLFYKA HTTGVPVMTP 660 VFFADPTDPK LRKVDDSFLL GSLLVKTWPT PKNRDSNAAF ELPKGIWQRF HFDDDHPELP 720 LLFLKGGSII PTGPVIQCVA EASPTDTVTL LIALDGKGDA TGVLYEDDGD GFGYKNGDYL 780 ITHYEARTVQ AADTKHGKIM IRVASTEGRR ERPKRTLHVR LLVGENVQSS LEEAYGGRHP 840 IMGVGAVKMP EDLDKGNVFV KVVPWLGGHI MSMIHKPSGY DWMEGRLENG GYEEFSGTEF 900 RSSGWNEEYK VVKRELAQTM GYEILGMEGD IGGGLVLARE ILLPRDSLNK VKISSSIVAR 960 SVGAGSGGFS RLVRLRIHPM FKIVHPMASY IKYTAIDGTA RELKPNMTFD DFSILGSDRP 1020 NGEWMLLDSE TGLAIVNTFD VKEVELCHVK WGPGSVTLEL WSEERPVSKD TPLSISHEYN 1080 LIDTTEEYA* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd06603 | GH31_GANC_GANAB_alpha | 3.0e-137 | 314 | 654 | 345 | + This family includes the closely related glycosyl hydrolase family 31 (GH31) isozymes, neutral alpha-glucosidase C (GANC) and the alpha subunit of heterodimeric neutral alpha-glucosidase AB (GANAB). Initially distinguished on the basis of differences in electrophoretic mobility in starch gel, GANC and GANAB have been shown to have other differences, including those of substrate specificity. GANC and GANAB are key enzymes in glycogen metabolism that hydrolyze terminal, non-reducing 1,4-linked alpha-D-glucose residues from glycogen in the endoplasmic reticulum. The GANC/GANAB family includes the alpha-glucosidase II (ModA) from Dictyostelium discoideum as well as the alpha-glucosidase II (GLS2, or ROT2 - Reversal of TOR2 lethality protein 2) from Saccharomyces cerevisiae. | ||
| COG1501 | COG1501 | 6.0e-148 | 197 | 798 | 624 | + Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism] | ||
| pfam01055 | Glyco_hydro_31 | 3.0e-173 | 300 | 730 | 451 | + Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases. | ||
| PLN02763 | PLN02763 | 0 | 136 | 1084 | 987 | + hydrolase, hydrolyzing O-glycosyl compounds | ||
| cd06604 | GH31_glucosidase_II_MalA | 0 | 314 | 654 | 342 | + Alpha-glucosidase II (alpha-D-glucoside glucohydrolase) is a glycosyl hydrolase family 31 (GH31) enzyme, found in bacteria and plants, which has exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. Alpha-glucosidase II has been characterized in Bacillus thermoamyloliquefaciens where it forms a homohexamer. This family also includes the MalA alpha-glucosidase from Sulfolobus sulfataricus and the AglA alpha-glucosidase from Picrophilus torridus. MalA is part of the carbohydrate-metabolizing machinery that allows this organism to utilize carbohydrates, such as maltose, as the sole carbon and energy source. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001752711.1 | 0 | 139 | 1089 | 1 | 969 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001760285.1 | 0 | 142 | 1082 | 8 | 1024 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001763366.1 | 0 | 136 | 1084 | 3 | 975 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001771658.1 | 0 | 144 | 1086 | 5 | 965 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001778632.1 | 0 | 204 | 1085 | 1 | 914 | predicted protein [Physcomitrella patens subsp. patens] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3w38_A | 0 | 232 | 707 | 229 | 723 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 3w37_A | 0 | 232 | 707 | 229 | 723 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2g3n_F | 0 | 179 | 731 | 29 | 609 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2g3n_E | 0 | 179 | 731 | 29 | 609 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2g3n_D | 0 | 179 | 731 | 29 | 609 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| starch degradation I | RXN-2141 | EC-3.2.1.20 | α-glucosidase |
