Basic Information | |
---|---|
Species | Physcomitrella patens |
Cazyme ID | Pp1s5_379V6.1 |
Family | GT47 |
Protein Properties | Length: 489 Molecular Weight: 55740.9 Isoelectric Point: 8.3756 |
Chromosome | Chromosome/Scaffold: 5 Start: 2831212 End: 2833002 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 90 | 433 | 0 |
SCQGRRVHMYDIPPSFNTALLQFCEGGLVHWIKFCKHYQNHGFGERVMASASMFRDDWYRTDAYMLEVIFFERMKSYQCLTDSPVNADIFYVPFFAGLDA LPYLYNESMRLQQQGLELLDWLRQNATESWRRYGGQDHFMIAGRTAWDFAHPEEGGKDWGTSLFDLDAMKHVTFMVLERRPWRPNEQAIPYPVGFHPSSS ASLELWIHRVRDTKRTALFSFSGALRPGQVGSIRDQLSQQCANASTKCSRLDCATIKCSHNPEPIYDSLLQADFCLQPRGDTATRRSTIDSIVSGCIPVL FHKDTAETQYTWHLPSDLDTYSVFIPEDCVMNGTCIVKDSLKQI |
Full Sequence |
---|
Protein Sequence Length: 489 Download |
MDTRSRKFRL MNPFKHYEVS GGRDGSSKSG SSWPMSAKFT PKIHKMSPPP KKKLAIKCCV 60 LFLIVLFTRW ACPSSGVPLS LHQLMLQSES CQGRRVHMYD IPPSFNTALL QFCEGGLVHW 120 IKFCKHYQNH GFGERVMASA SMFRDDWYRT DAYMLEVIFF ERMKSYQCLT DSPVNADIFY 180 VPFFAGLDAL PYLYNESMRL QQQGLELLDW LRQNATESWR RYGGQDHFMI AGRTAWDFAH 240 PEEGGKDWGT SLFDLDAMKH VTFMVLERRP WRPNEQAIPY PVGFHPSSSA SLELWIHRVR 300 DTKRTALFSF SGALRPGQVG SIRDQLSQQC ANASTKCSRL DCATIKCSHN PEPIYDSLLQ 360 ADFCLQPRGD TATRRSTIDS IVSGCIPVLF HKDTAETQYT WHLPSDLDTY SVFIPEDCVM 420 NGTCIVKDSL KQITPAQVRK MREKLISMIP NVLYRYPSGT DFAQTVTDAF DLAIEGMRQK 480 VDSLKASQ* |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-49 | 90 | 421 | 347 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_001752641.1 | 0 | 85 | 488 | 1 | 404 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001752721.1 | 0 | 91 | 487 | 100 | 490 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001761213.1 | 0 | 91 | 487 | 37 | 433 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001763405.1 | 0 | 89 | 480 | 1 | 386 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001773063.1 | 0 | 91 | 485 | 1 | 395 | predicted protein [Physcomitrella patens subsp. patens] |
EST Download unfiltered results here | ||||
---|---|---|---|---|
Hit | Length | Start | End | EValue |
CO162990 | 280 | 203 | 477 | 0 |
CJ974915 | 202 | 90 | 291 | 0 |
CF668912 | 286 | 202 | 486 | 0 |
BJ206962 | 180 | 131 | 310 | 0 |
DR480951 | 230 | 90 | 317 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
---|