Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s78_69V6.1 |
Family | AA3 |
Protein Properties | Length: 577 Molecular Weight: 61627.9 Isoelectric Point: 5.447 |
Chromosome | Chromosome/Scaffold: 78 Start: 426352 End: 429694 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 44 | 571 | 0 |
AAPPVATDFDYIIVGGGTAGCPLAATLSLNYSVLLLERGNTPYGNPDIESAANFGKLISNIQGNTWFSPVQSFQSQDGVFNRRARVLGGGSSINAGFYSR ASDDYVSRAGWDAGMVASAYEWVESVVAFFPRLQQWQTAVRDALLEVGVGPDNGRTYKHASGTKVGGSIFDEAGKRHTAADLLQFANPNNITVLLFANVH RILFAPPVPGSPPRAIGVVFSDVLGFQHQASLRQVEGSEVILAAGAIGSPHLLMTSGIGDADVLGPLGIPIVVNLTGVGKDMADNPANAIYVPSPNPVEV SLIETVGITNFGSFIETASGSQASLSQVGSLGIMAPWFRSEELVVKYAEALNNLPVRTQQILGQAGVILQKVDGPSSKGNLTLNQSNIEDNPLVQFNYFS EPEDLYTCIESTRMVKQILETEAMRNYTYTTLPETILNNAELVGNLIPTRLDVDTLSEWCRNTVITIWHYHGGCGVGTVVDNEHRIIGAVGIRVIDGSTF NSSPGTNPQATVMMLGRYMGLKIHQDRQ |
Full Sequence |
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Protein Sequence Length: 577 Download |
MATGIRLRIM RLLVAINLVI LSRLSQYSAN AAGGDYPFLK NASAAPPVAT DFDYIIVGGG 60 TAGCPLAATL SLNYSVLLLE RGNTPYGNPD IESAANFGKL ISNIQGNTWF SPVQSFQSQD 120 GVFNRRARVL GGGSSINAGF YSRASDDYVS RAGWDAGMVA SAYEWVESVV AFFPRLQQWQ 180 TAVRDALLEV GVGPDNGRTY KHASGTKVGG SIFDEAGKRH TAADLLQFAN PNNITVLLFA 240 NVHRILFAPP VPGSPPRAIG VVFSDVLGFQ HQASLRQVEG SEVILAAGAI GSPHLLMTSG 300 IGDADVLGPL GIPIVVNLTG VGKDMADNPA NAIYVPSPNP VEVSLIETVG ITNFGSFIET 360 ASGSQASLSQ VGSLGIMAPW FRSEELVVKY AEALNNLPVR TQQILGQAGV ILQKVDGPSS 420 KGNLTLNQSN IEDNPLVQFN YFSEPEDLYT CIESTRMVKQ ILETEAMRNY TYTTLPETIL 480 NNAELVGNLI PTRLDVDTLS EWCRNTVITI WHYHGGCGVG TVVDNEHRII GAVGIRVIDG 540 STFNSSPGTN PQATVMMLGR YMGLKIHQDR QRAGGV* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam05199 | GMC_oxred_C | 8.0e-21 | 418 | 559 | 147 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
TIGR03970 | Rv0697 | 1.0e-31 | 53 | 559 | 545 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
TIGR01810 | betA | 5.0e-33 | 53 | 559 | 556 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
COG2303 | BetA | 2.0e-47 | 48 | 573 | 573 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PLN02785 | PLN02785 | 0 | 8 | 576 | 596 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI34759.1 | 0 | 27 | 570 | 23 | 571 | unnamed protein product [Vitis vinifera] |
GenBank | EAY87068.1 | 0 | 10 | 575 | 1 | 578 | hypothetical protein OsI_08464 [Oryza sativa Indica Group] |
RefSeq | XP_001765687.1 | 0 | 32 | 566 | 1 | 535 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_002282510.1 | 0 | 39 | 570 | 1 | 537 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002510860.1 | 0 | 27 | 570 | 24 | 570 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3red_L | 0 | 29 | 573 | 2 | 521 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_K | 0 | 29 | 573 | 2 | 521 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_J | 0 | 29 | 573 | 2 | 521 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_I | 0 | 29 | 573 | 2 | 521 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_H | 0 | 29 | 573 | 2 | 521 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
cutin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |
cutin biosynthesis | RXN-9802 | EC-1.1.1 | 16-hydroxypalmitate dehydrogenase |
suberin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |