| Basic Information | |
|---|---|
| Species | Physcomitrella patens |
| Cazyme ID | Pp1s7_210V6.1 |
| Family | AA7 |
| Protein Properties | Length: 628 Molecular Weight: 69006.4 Isoelectric Point: 8.6991 |
| Chromosome | Chromosome/Scaffold: 7 Start: 1069965 End: 1071848 |
| Description | cytokinin oxidase/dehydrogenase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA7 | 162 | 610 | 0 |
| PVLGVQVEKVDDIQKAIKFAARHNLRVAVKSSGHDFLGRSTAHGSFLIWMHKFKNISIHDSFVPSSRCGKHSTPAVTVVGGVGWGEVTDALKPTGYITVS GNARTVCATGGYIQGGGHGSLSPQFGLAVDSVLQIEVVTADGKLRTTNACKDPELFFALLGGGGGTYGVVTSVTYKLHRSPSNFAGFFYVFSPPNGTVWS TATQEEILTIWARSSIALDEAMWGGYWVFNAQQFTLVFLAPSKLAAAKKIFTPILEELLQGKKVTLQFQYAFASSTFQDWHKTVEAIVSPKTGTDPVGDR VLMSSRIIPLSAMKDPRGTAKAILSALPVRNESLTTLIGNVVIGPGVRAADPSGLTAVTPAWREGIWHLIATHTWSWNSTEGQKSTIRNDLKAFAQALHK TYPDSGAYTNEASIDEPQWQRSFWGLSNYGRLIATKQRVDPQGLFVCSQ | |||
| Full Sequence |
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| Protein Sequence Length: 628 Download |
| MLNWMFRFRK KSRHAIPLIL LPSSWRLDQG YAMRGDQDSL GWPLYIMILY AVTVAVSYAS 60 AESYKCRCLD TNAACWPSKR ELNEFNCSVG GRLITPNPTG RPCHDPHYNP SLCQSLRNNY 120 FDAYLRADNA GSMQWENWED KGQETCSMDA PVSSKCHQGQ VPVLGVQVEK VDDIQKAIKF 180 AARHNLRVAV KSSGHDFLGR STAHGSFLIW MHKFKNISIH DSFVPSSRCG KHSTPAVTVV 240 GGVGWGEVTD ALKPTGYITV SGNARTVCAT GGYIQGGGHG SLSPQFGLAV DSVLQIEVVT 300 ADGKLRTTNA CKDPELFFAL LGGGGGTYGV VTSVTYKLHR SPSNFAGFFY VFSPPNGTVW 360 STATQEEILT IWARSSIALD EAMWGGYWVF NAQQFTLVFL APSKLAAAKK IFTPILEELL 420 QGKKVTLQFQ YAFASSTFQD WHKTVEAIVS PKTGTDPVGD RVLMSSRIIP LSAMKDPRGT 480 AKAILSALPV RNESLTTLIG NVVIGPGVRA ADPSGLTAVT PAWREGIWHL IATHTWSWNS 540 TEGQKSTIRN DLKAFAQALH KTYPDSGAYT NEASIDEPQW QRSFWGLSNY GRLIATKQRV 600 DPQGLFVCSQ CVGSEFWDET GNCPRRY* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN02441 | PLN02441 | 5.0e-6 | 171 | 321 | 169 | + cytokinin dehydrogenase | ||
| pfam08031 | BBE | 3.0e-8 | 568 | 606 | 39 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. | ||
| COG0277 | GlcD | 1.0e-15 | 160 | 606 | 467 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
| pfam01565 | FAD_binding_4 | 6.0e-19 | 166 | 309 | 145 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
| GO:0016491 | oxidoreductase activity |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001248265.1 | 0 | 51 | 616 | 12 | 563 | hypothetical protein CIMG_02036 [Coccidioides immitis RS] |
| RefSeq | XP_001263995.1 | 0 | 48 | 616 | 8 | 561 | FAD binding domain protein [Neosartorya fischeri NRRL 181] |
| RefSeq | XP_001753121.1 | 0 | 47 | 627 | 1 | 581 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001774865.1 | 0 | 75 | 617 | 1 | 493 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_753129.2 | 0 | 48 | 616 | 8 | 561 | FAD/FMN-containing protein [Aspergillus fumigatus Af293] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2bvh_D | 0.00000000000009 | 160 | 354 | 37 | 218 | A Chain A, Crystal Structure Of Choline Oxidase S101a Mutant |
| PDB | 2bvh_C | 0.00000000000009 | 160 | 354 | 37 | 218 | A Chain A, Crystal Structure Of Choline Oxidase S101a Mutant |
| PDB | 2bvh_B | 0.00000000000009 | 160 | 354 | 37 | 218 | A Chain A, Crystal Structure Of Choline Oxidase S101a Mutant |
| PDB | 2bvh_A | 0.00000000000009 | 160 | 354 | 37 | 218 | A Chain A, Crystal Structure Of Choline Oxidase S101a Mutant |
| PDB | 2bvg_D | 0.00000000000009 | 160 | 354 | 37 | 218 | A Chain A, Crystal Structure Of Choline Oxidase S101a Mutant |
| Transmembrane Domains | ||||
|---|---|---|---|---|
| Start | End | |||
| 39 | 61 | |||
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| DC930835 | 230 | 91 | 320 | 0 |
| DC945352 | 239 | 390 | 628 | 0 |
| DC946499 | 217 | 412 | 628 | 0 |
| EH092233 | 231 | 74 | 304 | 0 |
| FE448436 | 268 | 158 | 400 | 4e-33 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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