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Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s7_455V6.1 |
Family | GT47 |
Protein Properties | Length: 450 Molecular Weight: 51223.9 Isoelectric Point: 5.8769 |
Chromosome | Chromosome/Scaffold: 7 Start: 2755166 End: 2758722 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 78 | 371 | 0 |
RLKVFIYDIPSKYNTDWLKKDPRCLTHMFAVEEYLHDFLTESPVRTLNPEEADWFYTPVYTTCDLTPNGLPLPFKSPRVMRSAISYISSHWPYWNRTDGA DHFFVVPHDFAACFHYQEEKAIERGILPLLKRATLIQTFGQNHHVCLKEDSIVIPPYAPPERMQTRLNPPSTPRSIFAYFRGLFYDPGNDPEGGYYARGA RAAIWENFKDNPLFDISTEHPATYYEDMQRAIFCLCPLGWAPWSPRLVEGVIFGCIPVIIADDIVLPFADAIPWEKIGVFVEEKDVPILDKILC |
Full Sequence |
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Protein Sequence Length: 450 Download |
MEHPLECADS CSLAMSWFCN KKCRGWGLMK RTVVASGLRS VVLLLLFIYF VQDVTAEMGH 60 QRISGSAGDV LEDNPVGRLK VFIYDIPSKY NTDWLKKDPR CLTHMFAVEE YLHDFLTESP 120 VRTLNPEEAD WFYTPVYTTC DLTPNGLPLP FKSPRVMRSA ISYISSHWPY WNRTDGADHF 180 FVVPHDFAAC FHYQEEKAIE RGILPLLKRA TLIQTFGQNH HVCLKEDSIV IPPYAPPERM 240 QTRLNPPSTP RSIFAYFRGL FYDPGNDPEG GYYARGARAA IWENFKDNPL FDISTEHPAT 300 YYEDMQRAIF CLCPLGWAPW SPRLVEGVIF GCIPVIIADD IVLPFADAIP WEKIGVFVEE 360 KDVPILDKIL CTINHEEVLE KQRLLANPAM KQAMLFPRPA KPGDAFHQIL NGLARKLPHD 420 PSIYLQPGQS FLNWTEGPPG DLYPWGNDL* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-75 | 78 | 370 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABK26875.1 | 0 | 50 | 445 | 25 | 420 | unknown [Picea sitchensis] |
RefSeq | XP_001753186.1 | 0 | 1 | 449 | 1 | 449 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_002284685.1 | 0 | 39 | 445 | 5 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002318180.1 | 0 | 42 | 445 | 9 | 417 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002511079.1 | 0 | 44 | 445 | 11 | 417 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
GO846508 | 328 | 122 | 449 | 0 |
GO868810 | 329 | 91 | 419 | 0 |
GO872051 | 325 | 89 | 413 | 0 |
GT033383 | 309 | 137 | 445 | 0 |
ES900637 | 307 | 139 | 445 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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