Basic Information | |
---|---|
Species | Physcomitrella patens |
Cazyme ID | Pp1s80_88V6.1 |
Family | GT20 |
Protein Properties | Length: 892 Molecular Weight: 100737 Isoelectric Point: 6.1042 |
Chromosome | Chromosome/Scaffold: 80 Start: 569182 End: 572326 |
Description | trehalose phosphatase/synthase 5 |
View CDS |
External Links |
---|
NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT20 | 69 | 561 | 0 |
MSDENRMLVVAHMLPLNAHPHPSGNSYIFEWDKDSLLWQLKDGLPAGMEVVYVGCLKVEIDGPDQDEVAATLLENFNCVPAFLPEELKSKFYHGFCKQTL WPLFHYLLPLSPEHGGRFNRMWWQAYVSVNKIFADKVMEVISPDDDYVWVHDYHLMALPTFLRKRFNKVKLGFFLHSPFPSSEIYRTLPVRDEILRALLN ADLIGFHTFDYARHFLSCCSRMLGLEFVSKRGSIGVEYYGRSVGIKIMPVGIHMGQFDASLKLADTKWRIGEIQEKYKGRIVLLGVDDMDIFKGIGLKFL AMEELLRVHPQWRGQVVMVQIANPARGKGKDIEEAKNEAHAIADRVNEEYGFENYQPIVLVETHVPLFERIAYYTIAECCIVTAVRDGLNLIPYEYIVCR EGSPRLAGSENHLNDSSAKKSMLIVSEFIGCSPSLSGAIRVNPWNIEMVAEAMNVAITTKDQEKHLRHEKHYRYVSTHDVAYWAKTYISDLQR |
Full Sequence |
---|
Protein Sequence Length: 892 Download |
MVSRSYSNLL DLNEDSTISS DSSLGLTRSS GGRSSRAAIT GGPSGGTNHD DDRPVGHRDG 60 IFNTESFGMS DENRMLVVAH MLPLNAHPHP SGNSYIFEWD KDSLLWQLKD GLPAGMEVVY 120 VGCLKVEIDG PDQDEVAATL LENFNCVPAF LPEELKSKFY HGFCKQTLWP LFHYLLPLSP 180 EHGGRFNRMW WQAYVSVNKI FADKVMEVIS PDDDYVWVHD YHLMALPTFL RKRFNKVKLG 240 FFLHSPFPSS EIYRTLPVRD EILRALLNAD LIGFHTFDYA RHFLSCCSRM LGLEFVSKRG 300 SIGVEYYGRS VGIKIMPVGI HMGQFDASLK LADTKWRIGE IQEKYKGRIV LLGVDDMDIF 360 KGIGLKFLAM EELLRVHPQW RGQVVMVQIA NPARGKGKDI EEAKNEAHAI ADRVNEEYGF 420 ENYQPIVLVE THVPLFERIA YYTIAECCIV TAVRDGLNLI PYEYIVCREG SPRLAGSENH 480 LNDSSAKKSM LIVSEFIGCS PSLSGAIRVN PWNIEMVAEA MNVAITTKDQ EKHLRHEKHY 540 RYVSTHDVAY WAKTYISDLQ RTCNDNFKRR CYGIGFGLSF RVVALDPSFK KLRTELIVSA 600 YKRSVRRALL LDYDGTVMPT SHKESPSPEV LDLLNTLCSD PNNVVFIVSG RQRSKLAEWF 660 SSCEKLGLAA EHGYFYRWSR DSDWATCRLH SVSEWDRLNL VEREVPIMSF DWKLVVKPVM 720 QLYTESTDGS YIEDKESALV WNHRFADSDF GAWQAKELQD HLESVLANEP VTVKSGAHIV 780 EVTPQGVSKG VVVEKLLYMM EKEHGSLPDM VLCVGDDRSD EDMFESIESL MDHAPSAEVF 840 ACTVGQKPSK AKYYLDDVVE VIKMLQGLAN ASSRPSASSL PQLSDFSSLH I* 900 |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03063 | PLN03063 | 7.0e-168 | 74 | 878 | 841 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN02205 | PLN02205 | 0 | 1 | 875 | 883 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
pfam00982 | Glyco_transf_20 | 0 | 74 | 561 | 492 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
cd03788 | GT1_TPS | 0 | 74 | 560 | 487 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
PRK14501 | PRK14501 | 0 | 111 | 871 | 773 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX16014.1 | 0 | 1 | 891 | 1 | 862 | trehalose-6-phosphate synthase [Ginkgo biloba] |
GenBank | ABO61744.1 | 0 | 62 | 891 | 22 | 853 | trehalose-phosphate synthase 5 [Physcomitrella patens subsp. patens] |
RefSeq | XP_001765959.1 | 0 | 1 | 891 | 1 | 835 | trehalose-6-phosphate synthase [Physcomitrella patens subsp. patens] |
RefSeq | XP_001766049.1 | 0 | 75 | 891 | 1 | 817 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001772649.1 | 0 | 69 | 891 | 1 | 808 | trehalose-6-phosphate synthase [Physcomitrella patens subsp. patens] |
Annotations - PDB Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1gz5_D | 0 | 151 | 561 | 67 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_C | 0 | 151 | 561 | 67 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_B | 0 | 151 | 561 | 67 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_A | 0 | 151 | 561 | 67 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 2wtx_D | 0 | 151 | 561 | 68 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
Metabolic Pathways | |||
---|---|---|---|
Pathway Name | Reaction | EC | Protein Name |
trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
EST Download unfiltered results here | ||||
---|---|---|---|---|
Hit | Length | Start | End | EValue |
HO777775 | 802 | 91 | 883 | 0 |
HO779327 | 510 | 117 | 626 | 0 |
HO779327 | 266 | 622 | 883 | 0 |
HO797286 | 502 | 390 | 884 | 0 |
HO455803 | 485 | 392 | 874 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
---|