Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s81_200V6.1 |
Family | GT20 |
Protein Properties | Length: 854 Molecular Weight: 96745.4 Isoelectric Point: 5.2161 |
Chromosome | Chromosome/Scaffold: 81 Start: 1185055 End: 1188754 |
Description | trehalose phosphatase/synthase 5 |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 29 | 523 | 0 |
ASDDNDYRMLIVGHMLPLTASRGPDEQGWTFTWDEDSLALQLKAGLPKDMEVIYIGCLKVEVDDSEQDEVAATLLENFNCVPAFLPLEVRSRFYHGFCKQ MLWPLFHYMLPLSPEHGGRFNRSFWQAYVSVNKVFADKVMEVISPDDDYVWIHDYHLMVLPTFLRKRFNKVRLGFFLHSPFPSSEIYRTLPVRDEILRAL LNADLIGFHTFDYARHFLSCCSRMLGLEYESKRGYIGLEYYGRTVGIKILPVGIHMEQLNAGLRLADTEWRIAELRAEFKDRTVLLGVDDMDIFKGIGLK LLALEQLLRQHPKTRNRVVLVQIANPARGRGRDIEDLQNEAYTIAQRINDEFGNDDYQPVVLLERPVALYERIAYYTIAECCVVTAVRDGMNLIPYEYIA CREGSPELDAGVDRGPCPAPLKKSMLIVSEFIGCSPSLSGAIRVNPWNIEALAEAMNMSITLPDIEQQMRHEKHFRYVNTHDVAYWARSFMTDLV |
Full Sequence |
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Protein Sequence Length: 854 Download |
MAEGESREYP RGPVARGSRE DFVEASTAAS DDNDYRMLIV GHMLPLTASR GPDEQGWTFT 60 WDEDSLALQL KAGLPKDMEV IYIGCLKVEV DDSEQDEVAA TLLENFNCVP AFLPLEVRSR 120 FYHGFCKQML WPLFHYMLPL SPEHGGRFNR SFWQAYVSVN KVFADKVMEV ISPDDDYVWI 180 HDYHLMVLPT FLRKRFNKVR LGFFLHSPFP SSEIYRTLPV RDEILRALLN ADLIGFHTFD 240 YARHFLSCCS RMLGLEYESK RGYIGLEYYG RTVGIKILPV GIHMEQLNAG LRLADTEWRI 300 AELRAEFKDR TVLLGVDDMD IFKGIGLKLL ALEQLLRQHP KTRNRVVLVQ IANPARGRGR 360 DIEDLQNEAY TIAQRINDEF GNDDYQPVVL LERPVALYER IAYYTIAECC VVTAVRDGMN 420 LIPYEYIACR EGSPELDAGV DRGPCPAPLK KSMLIVSEFI GCSPSLSGAI RVNPWNIEAL 480 AEAMNMSITL PDIEQQMRHE KHFRYVNTHD VAYWARSFMT DLVRTCKGHA RRRCYGIGFG 540 LGFRVVALDP DFRRLRTDLI VSAYKKSTSR AILLDYDGTM IPQASINNPM PTPEVLSILN 600 TLCSDRKNFV VIVSGRPRQI LNECFSTCKR LGLAAEHGYF YRWHQDIDWV TCRYQRDDFD 660 EYENDRMEWK EIVEPVMQQY TESTDGSYIE EKESAMVWHH RDADPDFGSW QAKELQDHLD 720 SVLANQPVSV KSGAHIVEVK PQGVSKGVVV EELLAMMALK SAAPDFVLCI GDDRSDEDMF 780 ESIATVTARS GLAEVFACTV GQKPSKAKYY LDDIAEVIKL LQGIAAASDP GATPASLPTA 840 TSSQVSLETS LHI* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03063 | PLN03063 | 6.0e-169 | 36 | 829 | 831 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN02205 | PLN02205 | 0 | 36 | 829 | 801 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
pfam00982 | Glyco_transf_20 | 0 | 35 | 524 | 494 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
PRK14501 | PRK14501 | 0 | 36 | 827 | 799 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
cd03788 | GT1_TPS | 0 | 36 | 522 | 487 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX16014.1 | 0 | 36 | 851 | 60 | 868 | trehalose-6-phosphate synthase [Ginkgo biloba] |
GenBank | ABO61744.1 | 0 | 1 | 853 | 1 | 853 | trehalose-phosphate synthase 5 [Physcomitrella patens subsp. patens] |
RefSeq | XP_001766049.1 | 0 | 37 | 853 | 1 | 817 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001766932.1 | 0 | 78 | 853 | 1 | 778 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001772649.1 | 0 | 36 | 853 | 6 | 808 | trehalose-6-phosphate synthase [Physcomitrella patens subsp. patens] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1gz5_D | 0 | 121 | 522 | 75 | 450 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_C | 0 | 121 | 522 | 75 | 450 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_B | 0 | 121 | 522 | 75 | 450 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_A | 0 | 121 | 522 | 75 | 450 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 2wtx_D | 0 | 121 | 522 | 76 | 451 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO777775 | 789 | 46 | 829 | 0 |
HO779327 | 523 | 67 | 589 | 0 |
HO779327 | 246 | 588 | 830 | 0 |
HO797286 | 486 | 352 | 836 | 0 |
HO455803 | 468 | 359 | 825 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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