Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s88_178V6.1 |
Family | GT20 |
Protein Properties | Length: 779 Molecular Weight: 88459.1 Isoelectric Point: 5.5919 |
Chromosome | Chromosome/Scaffold: 88 Start: 1204582 End: 1207172 |
Description | trehalose phosphatase/synthase 5 |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 2 | 449 | 0 |
EVIYIGCLKVEVDDSEQDEVAATLLENFNCVPAFLPLDVRTRFYHGFCKQMLWPLFHYMLPLSPEHEGRFNRSFWQAYVSVNKVFADKVMEVISPDDDYV WIHDYHLMVLPTFLRKRFNKVRLGFFLHSPFPSSEIYRTLPVRDEILRALLNADLIGFHTFDYARHFLSCCSRMLGLEYESKRGYIGLEYYGRTVGIKIL PVGIHMEQLNAGLALADTEWRISELRTQYKNRTVFLGVDDMDIFKGIGLKFLALEQLLRQHPKLRNRVVLVQIANPARGRGRDIKDLQNEAYTIAQRIND EFGNEAEGYTPVVLLQRSVPFYERIAYYTIAECCVVTAVRDGMNLIPYEYIACREGSPDLDAVVDHGPGPAPLKKSMLIVSEFIGCSPSLSGAIRVNPWN IEALAEAMNMSITLPDIEQHMRHEKHFRYVNTHDVAYWARSFMTDLER |
Full Sequence |
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Protein Sequence Length: 779 Download |
MEVIYIGCLK VEVDDSEQDE VAATLLENFN CVPAFLPLDV RTRFYHGFCK QMLWPLFHYM 60 LPLSPEHEGR FNRSFWQAYV SVNKVFADKV MEVISPDDDY VWIHDYHLMV LPTFLRKRFN 120 KVRLGFFLHS PFPSSEIYRT LPVRDEILRA LLNADLIGFH TFDYARHFLS CCSRMLGLEY 180 ESKRGYIGLE YYGRTVGIKI LPVGIHMEQL NAGLALADTE WRISELRTQY KNRTVFLGVD 240 DMDIFKGIGL KFLALEQLLR QHPKLRNRVV LVQIANPARG RGRDIKDLQN EAYTIAQRIN 300 DEFGNEAEGY TPVVLLQRSV PFYERIAYYT IAECCVVTAV RDGMNLIPYE YIACREGSPD 360 LDAVVDHGPG PAPLKKSMLI VSEFIGCSPS LSGAIRVNPW NIEALAEAMN MSITLPDIEQ 420 HMRHEKHFRY VNTHDVAYWA RSFMTDLERT CKGHARRRCY GTGFGLGFRV VALDPDFRRL 480 RTDLIVSAYK KSMSRAILLD YDGTMIPQAS INNPMPTPEV LAMLKTLCND PKNFVVIVSG 540 RPRDILNECF SSCEELGLAA EHGFFYRWHR DEEWVTCRYQ REDFDDHEND HMEWKEIVEP 600 VMQQYTESTD GSYIEQKESA MVWHHRDADP DFGSWQAKEL QDHLESVLAN QPVTVKSGAH 660 IVEVKPQGVS KGVVVEELLA MMALKSAAPD FVLCVGDDRS DEDMFESIAT ATARSGLAEV 720 FACTVGQKPS KAKYYLDDIA EVIKLLQGLA AASDPGATPS GLPSATSSQV SLETSLHI* 780 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03063 | PLN03063 | 5.0e-174 | 2 | 754 | 789 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN02205 | PLN02205 | 0 | 1 | 754 | 759 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
pfam00982 | Glyco_transf_20 | 0 | 1 | 449 | 452 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
PRK14501 | PRK14501 | 0 | 12 | 752 | 746 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
cd03788 | GT1_TPS | 0 | 1 | 448 | 448 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX16014.1 | 0 | 1 | 776 | 102 | 868 | trehalose-6-phosphate synthase [Ginkgo biloba] |
GenBank | ABO61744.1 | 0 | 1 | 778 | 78 | 853 | trehalose-phosphate synthase 5 [Physcomitrella patens subsp. patens] |
RefSeq | XP_001766049.1 | 0 | 1 | 778 | 42 | 817 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001766932.1 | 0 | 1 | 778 | 1 | 778 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001772649.1 | 0 | 1 | 778 | 48 | 808 | trehalose-6-phosphate synthase [Physcomitrella patens subsp. patens] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2wtx_D | 0 | 44 | 449 | 76 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_C | 0 | 44 | 449 | 76 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_B | 0 | 44 | 449 | 76 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_A | 0 | 44 | 449 | 76 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 1uqu_B | 0 | 44 | 449 | 76 | 453 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO777775 | 758 | 1 | 754 | 0 |
HO779327 | 513 | 2 | 514 | 0 |
HO779327 | 246 | 513 | 755 | 0 |
HO797286 | 498 | 275 | 771 | 0 |
HO455803 | 474 | 282 | 750 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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