y
Basic Information | |
---|---|
Species | Physcomitrella patens |
Cazyme ID | Pp1s92_112V6.1 |
Family | GT47 |
Protein Properties | Length: 580 Molecular Weight: 64735.5 Isoelectric Point: 6.5386 |
Chromosome | Chromosome/Scaffold: 92 Start: 1336917 End: 1339142 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 248 | 529 | 0 |
ERRFKVYVYSEGEEPLVHNGPCKEIYAVEGRFIQELQGDNPFVTHDPDNAHVYFLPFSVAMMVAYLYEKESGDMDPLRLFVGDYVDVLMHKYPFWNRSGG ADHFMLSCHDWGPLITRENMNLGTRSIRVLCNANSSEGYVPWKDVSLPEIHLVGGHIPAELGGPPAKDRPHLAFFAGRDHGPVRPQLFKHWEGKDDDVIV YQWLPAHLKYHELMKTSRYCICPGGYEVNSPRIVEAIYNECVPVIIADSFILPFSDVLNWESFSLHVKESDIPNLKSILQNV |
Full Sequence |
---|
Protein Sequence Length: 580 Download |
MYRCATLLTV QTTLVVVLFL IGGVLVLDSY KWRQISIPWF SGLSEGPNAV LQQGNAAHTL 60 SGAVHTESVD GKPAQGSSAN FTTPAIGVPR NREDADHLPT SSPAPVITRL DAPSQPTVPT 120 HASPPRPEIQ SPSAEADAGT ASETVPRPSP LLPEFHNSSI SGPIPEPYLE TAAHPPLASP 180 RTAKKPPVLS TALDKLEYGL LQARFAIRHA YLAADKNDTP VDGGQGYDPH GDVYKSHAAF 240 RQSYREMERR FKVYVYSEGE EPLVHNGPCK EIYAVEGRFI QELQGDNPFV THDPDNAHVY 300 FLPFSVAMMV AYLYEKESGD MDPLRLFVGD YVDVLMHKYP FWNRSGGADH FMLSCHDWGP 360 LITRENMNLG TRSIRVLCNA NSSEGYVPWK DVSLPEIHLV GGHIPAELGG PPAKDRPHLA 420 FFAGRDHGPV RPQLFKHWEG KDDDVIVYQW LPAHLKYHEL MKTSRYCICP GGYEVNSPRI 480 VEAIYNECVP VIIADSFILP FSDVLNWESF SLHVKESDIP NLKSILQNVT METYTSMQER 540 VSQVQRHFVL HQPPKRYDVF HMILHSVWLR RLNLRVGFS* 600 |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PHA03307 | PHA03307 | 0.003 | 67 | 187 | 124 | + transcriptional regulator ICP4; Provisional | ||
pfam03016 | Exostosin | 1.0e-63 | 247 | 529 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI21064.1 | 0 | 197 | 577 | 95 | 478 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_001767346.1 | 0 | 1 | 242 | 87 | 328 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001767347.1 | 0 | 247 | 579 | 1 | 333 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_002515489.1 | 0 | 194 | 577 | 101 | 481 | catalytic, putative [Ricinus communis] |
RefSeq | XP_002524592.1 | 0 | 193 | 576 | 4 | 386 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
---|---|---|---|
Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |