| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb01g020060.1 |
| Family | GT47 |
| Protein Properties | Length: 460 Molecular Weight: 51111.3 Isoelectric Point: 8.5891 |
| Chromosome | Chromosome/Scaffold: 1 Start: 22005000 End: 22006395 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 64 | 400 | 0 |
| CRGRYIYVHDLPPRFNADVVQGCAAATDRWKDMCEDVRNAGLGRPLSGGALTGARFALDAIFHGRMRRYGCLTNDSSAAAAVFVPFYAGFEFARHVWGYD AAARDAASLDLVRWLVRRPEWRRAGGRDHFLVAGRTGWDFRRDVDDRNSTWGTSLFLLPAVKNMTFLVVETATMGWGNDLAVPYPTYFHPRTDSDVLSWQ QRIRSSERWWFMSFVGAARPSDPRSIRSQVMAQCGASPACRQLGCAFGSAQCHYPGDIMVLFQSSTFCLQPPGDSASRRSTFDAMVAGCIPVFFQPRSAY LQYRWHLPRDHATYSVFIPAEDVRSGNVSVEAELRKI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 460 Download |
| MVKPSAAVSR PCFLLVTAAA LWALTLYLRL LALMSVPVAF TGRVASFVPA PAADDTTNAS 60 GDPCRGRYIY VHDLPPRFNA DVVQGCAAAT DRWKDMCEDV RNAGLGRPLS GGALTGARFA 120 LDAIFHGRMR RYGCLTNDSS AAAAVFVPFY AGFEFARHVW GYDAAARDAA SLDLVRWLVR 180 RPEWRRAGGR DHFLVAGRTG WDFRRDVDDR NSTWGTSLFL LPAVKNMTFL VVETATMGWG 240 NDLAVPYPTY FHPRTDSDVL SWQQRIRSSE RWWFMSFVGA ARPSDPRSIR SQVMAQCGAS 300 PACRQLGCAF GSAQCHYPGD IMVLFQSSTF CLQPPGDSAS RRSTFDAMVA GCIPVFFQPR 360 SAYLQYRWHL PRDHATYSVF IPAEDVRSGN VSVEAELRKI PPAAIEKMRE EVIKLVPRLV 420 YADPRYKLET VKDAFDVAVD GVLERIAETE ESKTGSYWR* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 4.0e-59 | 63 | 400 | 352 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAO17347.1 | 0 | 62 | 459 | 227 | 632 | Hypothetical protein [Oryza sativa Japonica Group] |
| GenBank | EEE58313.1 | 0 | 62 | 459 | 261 | 666 | hypothetical protein OsJ_09380 [Oryza sativa Japonica Group] |
| RefSeq | NP_001048943.1 | 0 | 62 | 459 | 83 | 488 | Os03g0144300 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002464522.1 | 0 | 1 | 459 | 1 | 459 | hypothetical protein SORBIDRAFT_01g020060 [Sorghum bicolor] |
| RefSeq | XP_002468519.1 | 0 | 13 | 453 | 14 | 453 | hypothetical protein SORBIDRAFT_01g047290 [Sorghum bicolor] |
