| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb01g020070.1 |
| Family | GT47 |
| Protein Properties | Length: 614 Molecular Weight: 67558.8 Isoelectric Point: 6.5441 |
| Chromosome | Chromosome/Scaffold: 1 Start: 22010184 End: 22012025 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 179 | 522 | 0 |
| GQYIYVHELPARFNKDMVQNCDKLSPWTDMCRYTTNGGFGPLLRGGKGAFQGNGAGWYDTDEHALDIVFHERIKRYECLTDDPSLAAAVFVPFYAGLDVA RHLWGNNVSARDEMALDLASLLAKSPEWRAMGGRDHFFVAGRTTWDFRRKDDAHAEWGSRLLNLPAAKNMTALVVEASPWHLNDVAIPYPTSFHPASDED LFFWQDRVRALNRSYLFSFAGVPRPGDDKSIEGHLVDQCKASDSCSLMECSTTGPDNKCESPASVMKLFQSSTFCLLPRGATDTRRHAFDAMLAGCIPVF FHPGSAYVQYVWHLLKTHTDYSVYIPEDDVRTKNESVEEKLRKI | |||
| Full Sequence |
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| Protein Sequence Length: 614 Download |
| MKRHNAGELP LSSPAGDGKR LLANEEEAED KMDKYDKGRV RCSRLCFLFA VAATVSILAR 60 HCYDAGLGRG DSAGVVRIEA VPHGLPPPVH RERKIVPIAR GGEPSESRHS TSSPVDAGDD 120 ADTSSKPSAS RSDESANGGK TSSKQSSPSG AHAHTKQLGS HPFARALASA ADKDDLCGGQ 180 YIYVHELPAR FNKDMVQNCD KLSPWTDMCR YTTNGGFGPL LRGGKGAFQG NGAGWYDTDE 240 HALDIVFHER IKRYECLTDD PSLAAAVFVP FYAGLDVARH LWGNNVSARD EMALDLASLL 300 AKSPEWRAMG GRDHFFVAGR TTWDFRRKDD AHAEWGSRLL NLPAAKNMTA LVVEASPWHL 360 NDVAIPYPTS FHPASDEDLF FWQDRVRALN RSYLFSFAGV PRPGDDKSIE GHLVDQCKAS 420 DSCSLMECST TGPDNKCESP ASVMKLFQSS TFCLLPRGAT DTRRHAFDAM LAGCIPVFFH 480 PGSAYVQYVW HLLKTHTDYS VYIPEDDVRT KNESVEEKLR KIPPETVGAM RDAVVGLIPS 540 VTYGDATSRL ETTVKDAFDI AVAAVINKVT KLRRGIVEGR AEEEKMERYS WKYPLLAEGQ 600 KAEDHHEWDP LFN* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-59 | 176 | 522 | 362 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAM93699.1 | 0 | 42 | 612 | 15 | 595 | hypothetical protein [Oryza sativa Japonica Group] |
| GenBank | EEC67107.1 | 0 | 1 | 612 | 1 | 614 | hypothetical protein OsI_33904 [Oryza sativa Indica Group] |
| GenBank | EEE51089.1 | 0 | 1 | 612 | 1 | 583 | hypothetical protein OsJ_31792 [Oryza sativa Japonica Group] |
| RefSeq | NP_001064771.1 | 0 | 1 | 612 | 1 | 617 | Os10g0459700 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002464523.1 | 0 | 1 | 613 | 1 | 613 | hypothetical protein SORBIDRAFT_01g020070 [Sorghum bicolor] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| JG636298 | 266 | 250 | 515 | 0 |
| CX076275 | 263 | 253 | 515 | 0 |
| ES833008 | 285 | 330 | 613 | 0 |
| EL456596 | 261 | 235 | 495 | 0 |
| EE075461 | 256 | 285 | 540 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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