| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb01g042380.1 |
| Family | GT20 |
| Protein Properties | Length: 863 Molecular Weight: 97594.7 Isoelectric Point: 6.0108 |
| Chromosome | Chromosome/Scaffold: 1 Start: 65649583 End: 65653424 |
| Description | UDP-Glycosyltransferase / trehalose-phosphatase family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 55 | 546 | 0 |
| RPRTIIVANQLPIRSRRPASPEEPWTFEWDEDSLLRHLHHSSSPLMEFIYIGCLRDDIPQADQDAVAQALLETHNCVPAFLPTDIAERYYHGFCKQHLWP LFHYMLPLSPDLGGRFDRALWQAYVSANKIFADKVLEVINPDDDFVWVHDYHLMVLPTFLRKRFNRIKLGFFLHSPFPSSEIYKTLPVREELLRALLNSD LIGFHTFDYARHFLSCCGRMLGLSYESKRGHICLEYYGRTVSIKILPVGVHMEQLKTVLGLPETEAKVAELMEMYSGKGRVVMLGVDDMDIFKGISLKLL AMEELLRQHPEWRGKLVLVQVANPARGRGKDVAEVQTETYAMVGRINEVYGEPGYEPVVLIDEPLQFYERVAYYVIAEVCLVTAVRDGMNLIPYEYIVSR QGNEKLDGMLRQGKPEEKKSMLVVSEFIGCSPSLSGAIRVNPWNIEAVADAMETALVLPENEKRLRHDKHFRYVSTHDVGYWANSFLEDLKR | |||
| Full Sequence |
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| Protein Sequence Length: 863 Download |
| MASRSYSNLL DLATGAADQA PAAAAISALR RRLPRVVTNP GFIDDSPASP STPARPRTII 60 VANQLPIRSR RPASPEEPWT FEWDEDSLLR HLHHSSSPLM EFIYIGCLRD DIPQADQDAV 120 AQALLETHNC VPAFLPTDIA ERYYHGFCKQ HLWPLFHYML PLSPDLGGRF DRALWQAYVS 180 ANKIFADKVL EVINPDDDFV WVHDYHLMVL PTFLRKRFNR IKLGFFLHSP FPSSEIYKTL 240 PVREELLRAL LNSDLIGFHT FDYARHFLSC CGRMLGLSYE SKRGHICLEY YGRTVSIKIL 300 PVGVHMEQLK TVLGLPETEA KVAELMEMYS GKGRVVMLGV DDMDIFKGIS LKLLAMEELL 360 RQHPEWRGKL VLVQVANPAR GRGKDVAEVQ TETYAMVGRI NEVYGEPGYE PVVLIDEPLQ 420 FYERVAYYVI AEVCLVTAVR DGMNLIPYEY IVSRQGNEKL DGMLRQGKPE EKKSMLVVSE 480 FIGCSPSLSG AIRVNPWNIE AVADAMETAL VLPENEKRLR HDKHFRYVST HDVGYWANSF 540 LEDLKRTCSD HSQRRCWGIG FGLRFRVVSL DLHFRKLSLE SILMAYRRAK TRAILLDYDG 600 TLMPQAINKS PSTESVRILN SLCGDKKNVV YLCSGYDRRT LHEWFPCENL GIAAEHGYFL 660 RCKRDAEWKT CVTATDCSWK QIAEPVMCLY RETTDGSTIE DRETVLVWNY EDADPDFGSC 720 QAKELVDHLE SVLANEPVSV KTTPHSVEVK PQGVSKGLVA RRMLVSMKDR GQCPDFVLCI 780 GDDKSDEDMF QLIASAACGD SLGSKAEVFA CTVGRKPSKA KYYLDDAAEV VRLMQGLSYV 840 SEELALANHR DEDDDSSLDV WE* 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03064 | PLN03064 | 4.0e-166 | 59 | 819 | 793 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN02205 | PLN02205 | 0 | 1 | 843 | 856 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| pfam00982 | Glyco_transf_20 | 0 | 59 | 546 | 491 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| PRK14501 | PRK14501 | 0 | 125 | 838 | 717 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| cd03788 | GT1_TPS | 0 | 59 | 544 | 486 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAN52740.1 | 0 | 1 | 855 | 1 | 859 | Putative trehalose-6-phosphate synthase [Oryza sativa Japonica Group] |
| GenBank | ADA67991.1 | 0 | 1 | 850 | 1 | 850 | trehalose-6-phosphate synthase [Zea mays] |
| GenBank | EEC74792.1 | 0 | 1 | 855 | 1 | 859 | hypothetical protein OsI_10580 [Oryza sativa Indica Group] |
| RefSeq | NP_001049428.1 | 0 | 101 | 855 | 1 | 755 | Os03g0224300 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002465620.1 | 0 | 1 | 862 | 1 | 862 | hypothetical protein SORBIDRAFT_01g042380 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2wtx_D | 0 | 141 | 555 | 74 | 464 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_C | 0 | 141 | 555 | 74 | 464 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_B | 0 | 141 | 555 | 74 | 464 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_A | 0 | 141 | 555 | 74 | 464 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 1uqu_B | 0 | 141 | 555 | 74 | 464 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO777775 | 769 | 79 | 844 | 0 |
| HO779327 | 513 | 101 | 612 | 0 |
| HO779327 | 236 | 608 | 842 | 0 |
| HO797286 | 470 | 376 | 843 | 0 |
| HO795560 | 428 | 420 | 844 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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