| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb01g045550.2 |
| Family | GT47 |
| Protein Properties | Length: 784 Molecular Weight: 88604.4 Isoelectric Point: 6.8391 |
| Chromosome | Chromosome/Scaffold: 1 Start: 68638226 End: 68643025 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 337 | 691 | 0 |
| KKRPLIYVYDLPAEFDSHLLEGRHYRFQCVNRIYDDKNRTVWTQQLYGAQIALYESILASPHRTLNGDEADYFYVPVLDSCLITRSDDAPHLLLPRDLRR RSYHALEYYRMAYDHIAQQYPYWNRTSGRDHIWFFSWDEGACYAPKEIWNSMMLVHWGNTNTKHKNSTTAYWADNWDDIPLDKRGNHPCFDPRKDLVLPA WKEPNPGAIWLKLWARPRKNRTTLFYFNGNLGSAYEGGRPEDTYSMGIRQKLAAEFGSTPNKQGSLGRQHAADVTVTYLRTEKYYEELASSVFCGVLPGD GWSGRMEDSMLQGCIPVIIQDGIFLPYENALNYNSFAVRIQEDDIPGLISTLRGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 784 Download |
| MLAIRSTKCP VAFVGVAGAL VVLVTAVHVF MVPILPASLD YFGARSSISR PNNVLPAVGV 60 VDSRLRGRFP SDSYGAVAFR GAPWKAEIGR WLAGCHANSS SVDVTEAIGA KRCEKDCSGR 120 GVCNYNLGEC RCFHGYSGKG CEEVLKLECN LPSSPEWPVG LWIVSTCAAH CDKTRAMCFC 180 GPGTKYPDRP VAEACGFKTI LPAKPDDPKL TDWKTPDLEN IFTTNSSELG WCNVVPEDAY 240 SSKVKFKEEC DCKYDGLWGQ FCETRVECSC INQCSGHGHC HGGFCQCDSG YFGIDCSIPS 300 AYSLTHDWPS WLQTPVNSPD LKILNSTTID VKAVVQKKRP LIYVYDLPAE FDSHLLEGRH 360 YRFQCVNRIY DDKNRTVWTQ QLYGAQIALY ESILASPHRT LNGDEADYFY VPVLDSCLIT 420 RSDDAPHLLL PRDLRRRSYH ALEYYRMAYD HIAQQYPYWN RTSGRDHIWF FSWDEGACYA 480 PKEIWNSMML VHWGNTNTKH KNSTTAYWAD NWDDIPLDKR GNHPCFDPRK DLVLPAWKEP 540 NPGAIWLKLW ARPRKNRTTL FYFNGNLGSA YEGGRPEDTY SMGIRQKLAA EFGSTPNKQG 600 SLGRQHAADV TVTYLRTEKY YEELASSVFC GVLPGDGWSG RMEDSMLQGC IPVIIQDGIF 660 LPYENALNYN SFAVRIQEDD IPGLISTLRG INNTQVEFML GNVRQIWQRF FYRDSILLEA 720 QRQKGLFSEE APWSVEVSKL PHDDDAFATF IQVLHYKLYN DPWRQGLLQT KETRLPNICS 780 RTS* 840 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 8.0e-70 | 336 | 691 | 359 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005515 | protein binding |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI29877.1 | 0 | 4 | 772 | 33 | 809 | unnamed protein product [Vitis vinifera] |
| GenBank | EAZ25771.1 | 0 | 4 | 783 | 1 | 779 | hypothetical protein OsJ_09611 [Oryza sativa Japonica Group] |
| GenBank | EEC74609.1 | 0 | 4 | 783 | 1 | 737 | hypothetical protein OsI_10218 [Oryza sativa Indica Group] |
| RefSeq | NP_191322.3 | 0 | 14 | 779 | 14 | 788 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002277596.1 | 0 | 4 | 772 | 5 | 781 | PREDICTED: hypothetical protein [Vitis vinifera] |
