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Basic Information | |
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Species | Sorghum bicolor |
Cazyme ID | Sb01g047290.1 |
Family | GT47 |
Protein Properties | Length: 487 Molecular Weight: 54749.1 Isoelectric Point: 7.4024 |
Chromosome | Chromosome/Scaffold: 1 Start: 70375937 End: 70377397 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 51 | 400 | 0 |
CRGRYIYMHDLPPRFNADIISNCRKTEDHWGDMCGALSNAGLGRPLADRTDGVLKSEAGWYATHQFALDSIFHNRMKQYECLTNHSAVAAAVFVPFYAGF DFVRYHWGYDNAARDAASVDLTKWLMARPEWRRMGGRDHFLVAGRTGWDFRRSNNVNPDWGTDLLVMPAGRNMSVLVLESAMLHGNDYPVPYPTYFHPRS DADVLRWQDRVRGQHRTWLMAFVGAPRPDVPINIRVRDHVIAQCKASSACTMLGCARATGSTQCHTPGNIMRLFQKTTFCLQPPGDTCTRRSAFDSMVAG CIPVFFHPGSAYKQYRWHLPMDDHLRYSVYIPDADVRERNVSIEAVLRAI |
Full Sequence |
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Protein Sequence Length: 487 Download |
MEKAAANALP PLRFLAVLAV TAWTFFLYFH FSVISGTVEV SHGDDDGADR CRGRYIYMHD 60 LPPRFNADII SNCRKTEDHW GDMCGALSNA GLGRPLADRT DGVLKSEAGW YATHQFALDS 120 IFHNRMKQYE CLTNHSAVAA AVFVPFYAGF DFVRYHWGYD NAARDAASVD LTKWLMARPE 180 WRRMGGRDHF LVAGRTGWDF RRSNNVNPDW GTDLLVMPAG RNMSVLVLES AMLHGNDYPV 240 PYPTYFHPRS DADVLRWQDR VRGQHRTWLM AFVGAPRPDV PINIRVRDHV IAQCKASSAC 300 TMLGCARATG STQCHTPGNI MRLFQKTTFC LQPPGDTCTR RSAFDSMVAG CIPVFFHPGS 360 AYKQYRWHLP MDDHLRYSVY IPDADVRERN VSIEAVLRAI PPATVERMRE EVIRLIPRVL 420 YADPRSKLET VKDAVDVAVE GILDTVARIN NGEYVDSGGP VTEDPPNLFA STESRFRPVQ 480 SVQADQ* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-54 | 55 | 400 | 356 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAO17347.1 | 0 | 1 | 452 | 178 | 625 | Hypothetical protein [Oryza sativa Japonica Group] |
RefSeq | NP_001048943.1 | 0 | 1 | 452 | 34 | 481 | Os03g0144300 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002465869.1 | 0 | 3 | 476 | 43 | 515 | hypothetical protein SORBIDRAFT_01g047310 [Sorghum bicolor] |
RefSeq | XP_002468519.1 | 0 | 1 | 486 | 1 | 486 | hypothetical protein SORBIDRAFT_01g047290 [Sorghum bicolor] |
RefSeq | XP_002468520.1 | 0 | 3 | 484 | 7 | 478 | hypothetical protein SORBIDRAFT_01g047300 [Sorghum bicolor] |