| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb01g047310.1 |
| Family | GT47 |
| Protein Properties | Length: 535 Molecular Weight: 59553.3 Isoelectric Point: 9.7576 |
| Chromosome | Chromosome/Scaffold: 1 Start: 70396763 End: 70398849 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 90 | 439 | 0 |
| CRGRYIYMHDLPPRFNADIIRNDCRNTEGHWGDICASLSNGGLGRPLADDGGVITGGAGWYSTHQFALDIIFHNRMKQYECLTNHPAVASAVFVPFYAGF DFARYHWGYDNATRDAASVDLTRWLMARPQWQRMGGRDHFLVAGRTGWDFRRISNLGADWGNDLLVIPGARNMSVLVLESTLKRGTDFSVPYPTYFHPRS DADVLRWQDRVRRRRRTWLMAFVGAPRPDVQMSIRVRDHVIAQCKASGACAMLSCARTPSSTQCHTPANIMRLFQKAVFCLQPPGDSPTRRSVFDSMVAG CIPVFFHTGSAYKQYPWHLPKDDHLKYSVYIPTADVRRRNVSIEAVLRAI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 535 Download |
| MYVQSAIRLH APVSIVNLVK SGRKSGGNAR SRRAVEMKGI EIKAAANVLP PPRILAALAL 60 AAWTFFLYVH FSMISGTVEV NNVEGLADPC RGRYIYMHDL PPRFNADIIR NDCRNTEGHW 120 GDICASLSNG GLGRPLADDG GVITGGAGWY STHQFALDII FHNRMKQYEC LTNHPAVASA 180 VFVPFYAGFD FARYHWGYDN ATRDAASVDL TRWLMARPQW QRMGGRDHFL VAGRTGWDFR 240 RISNLGADWG NDLLVIPGAR NMSVLVLEST LKRGTDFSVP YPTYFHPRSD ADVLRWQDRV 300 RRRRRTWLMA FVGAPRPDVQ MSIRVRDHVI AQCKASGACA MLSCARTPSS TQCHTPANIM 360 RLFQKAVFCL QPPGDSPTRR SVFDSMVAGC IPVFFHTGSA YKQYPWHLPK DDHLKYSVYI 420 PTADVRRRNV SIEAVLRAIP PATVVRMQQE VIRLIPSLLY ADPRSKLETV KDAVDVAVDG 480 ILDTVARIKN GEDVNCGGPV DKDPPNLFAS TASRFFSGGI WQAARYVSLW QSGI* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-65 | 89 | 439 | 361 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_001048943.1 | 0 | 17 | 491 | 15 | 481 | Os03g0144300 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002465869.1 | 0 | 1 | 534 | 1 | 534 | hypothetical protein SORBIDRAFT_01g047310 [Sorghum bicolor] |
| RefSeq | XP_002468519.1 | 0 | 43 | 515 | 3 | 476 | hypothetical protein SORBIDRAFT_01g047290 [Sorghum bicolor] |
| RefSeq | XP_002468520.1 | 0 | 37 | 525 | 1 | 480 | hypothetical protein SORBIDRAFT_01g047300 [Sorghum bicolor] |
| RefSeq | XP_002468521.1 | 0 | 21 | 523 | 4 | 505 | hypothetical protein SORBIDRAFT_01g047315 [Sorghum bicolor] |
| Hydropathy |
|---|
 |
| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| CN129746 | 180 | 356 | 535 | 0 |
| EL456596 | 264 | 148 | 411 | 0 |
| JG636298 | 269 | 164 | 432 | 0 |
| EL472986 | 257 | 155 | 411 | 0 |
| CX076275 | 266 | 167 | 432 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
|---|
 |
