| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb01g050110.1 |
| Family | GT47 |
| Protein Properties | Length: 430 Molecular Weight: 48556.4 Isoelectric Point: 9.8543 |
| Chromosome | Chromosome/Scaffold: 1 Start: 73068797 End: 73070793 |
| Description | FRA8 homolog |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 74 | 370 | 0 |
| PVRIYVYDLPARFNRDWAAADARCARHLFAAEVAVHEALLAYAGRAARPEDADLFFVPVYVSCNFSTPNGFPSLSHARGLLAEAVDLVRVRMPYWNRSAG ADHVFVASHDFGACFHPMEDVAIADGIPEFLKRSILLQTFGVQGHHVCQEVEHVVIPPHVPPEVAHELPEPEKAQRDIFAFFRGKMEVHPKNISGRFYSK KVRTELLQHYGRNRKFYLKRKRFDNYRSEMARSLFCLCPLGWAPWSPRLVESVLLGCIPVIIADNIRLPFPSVLQWPEISLQVAEKDIANLEMVLDH | |||
| Full Sequence |
|---|
| Protein Sequence Length: 430 Download |
| MRDPKPRRSQ AAPTLAAKLR KHSTCLLLLL WFALSLCLFL SAAPPAAAPL SRSSFLRSKP 60 RALAATTTGA AASPVRIYVY DLPARFNRDW AAADARCARH LFAAEVAVHE ALLAYAGRAA 120 RPEDADLFFV PVYVSCNFST PNGFPSLSHA RGLLAEAVDL VRVRMPYWNR SAGADHVFVA 180 SHDFGACFHP MEDVAIADGI PEFLKRSILL QTFGVQGHHV CQEVEHVVIP PHVPPEVAHE 240 LPEPEKAQRD IFAFFRGKME VHPKNISGRF YSKKVRTELL QHYGRNRKFY LKRKRFDNYR 300 SEMARSLFCL CPLGWAPWSP RLVESVLLGC IPVIIADNIR LPFPSVLQWP EISLQVAEKD 360 IANLEMVLDH VVATNLTMIQ KNLWDPVKRK ALVFNRPMEV GDATWQVLRE LEVLLDQSQR 420 RRYVGSWRR* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-54 | 73 | 368 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAN62780.1 | 0 | 59 | 429 | 60 | 449 | Unknown protein [Oryza sativa Japonica Group] |
| GenBank | ACN31903.1 | 0 | 1 | 428 | 1 | 427 | unknown [Zea mays] |
| RefSeq | NP_001048697.1 | 0 | 59 | 429 | 60 | 427 | Os03g0107900 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_197685.2 | 0 | 29 | 428 | 50 | 465 | F8H (FRA8 HOMOLOG); catalytic [Arabidopsis thaliana] |
| RefSeq | XP_002468679.1 | 0 | 1 | 429 | 1 | 429 | hypothetical protein SORBIDRAFT_01g050110 [Sorghum bicolor] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
