y
Basic Information | |
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Species | Sorghum bicolor |
Cazyme ID | Sb01g050380.1 |
Family | GT47 |
Protein Properties | Length: 482 Molecular Weight: 53098.7 Isoelectric Point: 9.2403 |
Chromosome | Chromosome/Scaffold: 1 Start: 73432950 End: 73434395 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 45 | 403 | 0 |
CAGRRIHIRRLPASFNTQLLLYCGSGSGSGTAFPLADPGDSKWSVPACASLANHGLGPRTHNGTRSWYRTDARLLEPFFHRRLLEHQCLVSRPAQADAVF LPYYAALDALPYVLHPDLLNSSALHGVPLARFLAHHQPRVLARRHGHDHFFLLAGTAWDYSQPHDADPRLYGTTSLLRLPDLANFTVLTLESRAWPWQEH AIPHPTSFHPSSLPRLRSWIARARRSRRTALMLYAGGVSRPSRPNIRGAILAECANRTTSSPDVCTVVDCSAAACGLNPVAYMRPMLKANFCLQPPGDSP SRRSTFDAIVAGCIPVFFEHAAARAHYGWHLPRGRYDQFSVTIPKESVVMGDVRIADVL |
Full Sequence |
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Protein Sequence Length: 482 Download |
MAARLLLTLL LCSVVITGAS SRKKKTSLAV AVPVAPPPDG PPDPCAGRRI HIRRLPASFN 60 TQLLLYCGSG SGSGTAFPLA DPGDSKWSVP ACASLANHGL GPRTHNGTRS WYRTDARLLE 120 PFFHRRLLEH QCLVSRPAQA DAVFLPYYAA LDALPYVLHP DLLNSSALHG VPLARFLAHH 180 QPRVLARRHG HDHFFLLAGT AWDYSQPHDA DPRLYGTTSL LRLPDLANFT VLTLESRAWP 240 WQEHAIPHPT SFHPSSLPRL RSWIARARRS RRTALMLYAG GVSRPSRPNI RGAILAECAN 300 RTTSSPDVCT VVDCSAAACG LNPVAYMRPM LKANFCLQPP GDSPSRRSTF DAIVAGCIPV 360 FFEHAAARAH YGWHLPRGRY DQFSVTIPKE SVVMGDVRIA DVLAAVPEDK VARMRERVLE 420 MAPRVVYRRH GSAAELRDST SYRDAVDLAV EGVLRRIRRR VSALEDAQPD AIYELEEDDD 480 D* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-42 | 103 | 393 | 303 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAG13471.2 | 0 | 43 | 478 | 30 | 459 | AC026758_8 hypothetical protein [Oryza sativa Japonica Group] |
GenBank | ACF22751.1 | 0 | 42 | 481 | 36 | 460 | exostosin family protein [Brachypodium distachyon] |
GenBank | ACN36955.1 | 0 | 42 | 481 | 26 | 454 | unknown [Zea mays] |
RefSeq | XP_002466037.1 | 0 | 1 | 481 | 1 | 481 | hypothetical protein SORBIDRAFT_01g050380 [Sorghum bicolor] |
RefSeq | XP_002467522.1 | 0 | 34 | 481 | 14 | 449 | hypothetical protein SORBIDRAFT_01g029520 [Sorghum bicolor] |