| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb02g003610.1 |
| Family | CE10 |
| Protein Properties | Length: 351 Molecular Weight: 36719.8 Isoelectric Point: 5.9503 |
| Chromosome | Chromosome/Scaffold: 2 Start: 4039144 End: 4040200 |
| Description | alpha/beta-Hydrolases superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| CE10 | 56 | 329 | 0 |
| VQWKEAVYDKAKNLRVRMYKPTTTASAAAGKKLPVLVHFHGGGFCLGSCTWANVHEFCLRLAADAGAVVLSAGYRLAPEHRLPAAFDDGAGFMRWLRDQS VAAADGWLAEAAADFGRVFVTGDSAGGTIAHHLAVRAAAEPEPEPGHVTVRGYVLLMPFFGGVRRTASEAECPEEAFPNLDLVDRFWRLSLPAGATRDHP AANPFGPDSPDLGSVDFPPVLVVVGGLDLIRDRTVDYAERLAAMGKPVEVAKFAGKPHGFYLHEPGSEATGELI | |||
| Full Sequence |
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| Protein Sequence Length: 351 Download |
| MPAVSAAACC AAAAPATEVA EDLFGFLRVL SDGTVLRSPA GPVFCPTTFP GSHPSVQWKE 60 AVYDKAKNLR VRMYKPTTTA SAAAGKKLPV LVHFHGGGFC LGSCTWANVH EFCLRLAADA 120 GAVVLSAGYR LAPEHRLPAA FDDGAGFMRW LRDQSVAAAD GWLAEAAADF GRVFVTGDSA 180 GGTIAHHLAV RAAAEPEPEP GHVTVRGYVL LMPFFGGVRR TASEAECPEE AFPNLDLVDR 240 FWRLSLPAGA TRDHPAANPF GPDSPDLGSV DFPPVLVVVG GLDLIRDRTV DYAERLAAMG 300 KPVEVAKFAG KPHGFYLHEP GSEATGELIQ TVARFVDGCG AVVAASEAAA * 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG2272 | PnbA | 7.0e-6 | 80 | 185 | 121 | + Carboxylesterase type B [Lipid metabolism] | ||
| cd00312 | Esterase_lipase | 6.0e-6 | 69 | 188 | 133 | + Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These catalytic residues are responsible for the nucleophilic attack on the carbonyl carbon atom of the ester bond. In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate. | ||
| PRK10162 | PRK10162 | 2.0e-9 | 71 | 185 | 116 | + acetyl esterase; Provisional | ||
| COG0657 | Aes | 1.0e-27 | 50 | 317 | 270 | + Esterase/lipase [Lipid metabolism] | ||
| pfam07859 | Abhydrolase_3 | 2.0e-56 | 91 | 317 | 228 | + alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008152 | metabolic process |
| GO:0016787 | hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EAZ02866.1 | 0 | 15 | 337 | 16 | 344 | hypothetical protein OsI_24997 [Oryza sativa Indica Group] |
| RefSeq | NP_001132851.1 | 0 | 17 | 350 | 17 | 351 | hypothetical protein LOC100194343 [Zea mays] |
| RefSeq | XP_002459376.1 | 0 | 1 | 339 | 4 | 359 | hypothetical protein SORBIDRAFT_02g003600 [Sorghum bicolor] |
| RefSeq | XP_002461499.1 | 0 | 1 | 350 | 1 | 350 | hypothetical protein SORBIDRAFT_02g003610 [Sorghum bicolor] |
| RefSeq | XP_002461500.1 | 0 | 1 | 339 | 10 | 359 | hypothetical protein SORBIDRAFT_02g003620 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3ed1_F | 0 | 60 | 337 | 66 | 348 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 3ed1_E | 0 | 60 | 337 | 66 | 348 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 3ed1_D | 0 | 60 | 337 | 66 | 348 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 3ed1_C | 0 | 60 | 337 | 66 | 348 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 3ed1_B | 0 | 60 | 337 | 66 | 348 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| formononetin biosynthesis | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| formononetin biosynthesis | RXN-3625 | - | 2,7-dihydroxy-4'-methoxyisoflavanone dehydratase |
| isoflavonoid biosynthesis I | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-3303 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-5502 | - | 2,7,5-trihydroxy-4'-methoxyisoflavanone dehydratase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| FL748147 | 237 | 22 | 247 | 0 |
| FE644698 | 218 | 22 | 231 | 0 |
| DV025018 | 223 | 22 | 236 | 0 |
| EC886789 | 212 | 22 | 232 | 0 |
| CN129143 | 225 | 22 | 237 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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