| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb02g005180.1 |
| Family | GT47 |
| Protein Properties | Length: 585 Molecular Weight: 63602.9 Isoelectric Point: 8.8003 |
| Chromosome | Chromosome/Scaffold: 2 Start: 6026487 End: 6030410 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 235 | 530 | 0 |
| EKQLKVYVYEEGEPPVFHDGPCRSIYSTEGRFIHAMETATRLRTSDPSQAHVFFLPFSVVKMVKTIYEPGSHDMAPLKRTVADYLRVISDKYPFWNRSAG ADHFMLSCHDWGPYVSSANAELFGNSIRVLCNANTSEGFDLAKDVSLPEINLRSDAVERQVGGPSASRRPFLAFFAGGNHGPVRPALLAHWGPGSGREDD PDVRVSEYLPTRGGRAGASAAAYTDMMRRSRFCLCPGGYEVASPRLAEAVYLECVPVVVDDGEYALPFADVLNWDAFAVRVRVADVPRIKEILSAV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 585 Download |
| MRATTSAAAP CLPWLRSHGR ASSAAAYTAV AACLLALVTF LVVAAFWDPR TQASTWFLSS 60 SSSSSASSLT TAGGVGGEHL LATASSYYSD GGGGGGRNST GKEVHEEVRG QGGDDDGFLS 120 LVNSSSGGYG APPPHQISVT RQPPASAPAP AALAPAASPV TGNSDEVIRA TPQVQRSSDI 180 KLERLELGLA KARSAIMEAI RNKDKRSPLP DKDYVPMGPI YRNAHAFHRS YLEMEKQLKV 240 YVYEEGEPPV FHDGPCRSIY STEGRFIHAM ETATRLRTSD PSQAHVFFLP FSVVKMVKTI 300 YEPGSHDMAP LKRTVADYLR VISDKYPFWN RSAGADHFML SCHDWGPYVS SANAELFGNS 360 IRVLCNANTS EGFDLAKDVS LPEINLRSDA VERQVGGPSA SRRPFLAFFA GGNHGPVRPA 420 LLAHWGPGSG REDDPDVRVS EYLPTRGGRA GASAAAYTDM MRRSRFCLCP GGYEVASPRL 480 AEAVYLECVP VVVDDGEYAL PFADVLNWDA FAVRVRVADV PRIKEILSAV SPRQYIRMQR 540 RVRMVRRHFM VHGGPPRRYD AFHMILHSVW LRRLNVRIDA HAQG* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-52 | 234 | 530 | 314 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAB08605.1 | 0 | 181 | 578 | 27 | 405 | unnamed protein product [Arabidopsis thaliana] |
| GenBank | EAZ03045.1 | 0 | 48 | 580 | 48 | 598 | hypothetical protein OsI_25187 [Oryza sativa Indica Group] |
| RefSeq | NP_001059081.1 | 0 | 48 | 580 | 48 | 603 | Os07g0188700 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002459470.1 | 0 | 1 | 584 | 1 | 584 | hypothetical protein SORBIDRAFT_02g005180 [Sorghum bicolor] |
| RefSeq | XP_002524591.1 | 0 | 149 | 579 | 89 | 503 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
