| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb02g009370.1 |
| Family | GH18 |
| Protein Properties | Length: 298 Molecular Weight: 31540.2 Isoelectric Point: 4.3699 |
| Chromosome | Chromosome/Scaffold: 2 Start: 13417051 End: 13417944 |
| Description | chitinase A |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH18 | 28 | 285 | 9.2e-31 |
| ISIYWGQNGGEGTLADTCATGNYKFVNLAFLVAFGNGQQPVLNLAGHCDPSSGGCTSLSDDIKSCQSNGVKVMLSIGGASGSYYLTSAADAKTVATYLWN NFLGGQSSSRPLGDAVLDGIDFDIEGGTTQHWDDLARYLKGYSNSGRRVYLTAAPQCPFPDAYVGDALNTGQFDYVWVQFYNNPPCQYSSGSTTDLADAW KQWLSIPAKQVFLGLPASPEAAGSGFIPADDLKSQVLPLIKSSGKYGGIMLWSKYYDD | |||
| Full Sequence |
|---|
| Protein Sequence Length: 298 Download |
| MATRSSLVPL LLITVVVAQI VGSQAGSISI YWGQNGGEGT LADTCATGNY KFVNLAFLVA 60 FGNGQQPVLN LAGHCDPSSG GCTSLSDDIK SCQSNGVKVM LSIGGASGSY YLTSAADAKT 120 VATYLWNNFL GGQSSSRPLG DAVLDGIDFD IEGGTTQHWD DLARYLKGYS NSGRRVYLTA 180 APQCPFPDAY VGDALNTGQF DYVWVQFYNN PPCQYSSGST TDLADAWKQW LSIPAKQVFL 240 GLPASPEAAG SGFIPADDLK SQVLPLIKSS GKYGGIMLWS KYYDDQDDYS SSVKSDV* 300 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd06543 | GH18_PF-ChiA-like | 2.0e-10 | 51 | 167 | 125 | + PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain. Members of this domain family are found not only in archaea but also in eukaryotes and prokaryotes. PF-ChiA exhibits hydrolytic activity toward both colloidal and crystalline (beta/alpha) chitins at high temperature. | ||
| COG3469 | COG3469 | 1.0e-11 | 49 | 279 | 264 | + Chitinase [Carbohydrate transport and metabolism] | ||
| cd02871 | GH18_chitinase_D-like | 5.0e-17 | 31 | 279 | 305 | + GH18 domain of Chitinase D (ChiD). ChiD, a chitinase found in Bacillus circulans, hydrolyzes the 1,4-beta-linkages of N-acetylglucosamine in chitin and chitodextrins. The domain architecture of ChiD includes a catalytic glycosyl hydrolase family 18 (GH18) domain, a chitin-binding domain, and a fibronectin type III domain. The chitin-binding and fibronectin type III domains are located either N-terminal or C-terminal to the catalytic domain. This family includes exochitinase Chi36 from Bacillus cereus. | ||
| pfam00704 | Glyco_hydro_18 | 3.0e-32 | 26 | 278 | 276 | + Glycosyl hydrolases family 18. | ||
| cd02877 | GH18_hevamine_XipI_class_III | 1.0e-133 | 26 | 279 | 263 | + This conserved domain family includes xylanase inhibitor Xip-I, and the class III plant chitinases such as hevamine, concanavalin B, and PPL2, all of which have a glycosyl hydrolase family 18 (GH18) domain. Hevamine is a class III endochitinase that hydrolyzes the linear polysaccharide chains of chitin and peptidoglycan and is important for defense against pathogenic bacteria and fungi. PPL2 (Parkia platycephala lectin 2) is a class III chitinase from Parkia platycephala seeds that hydrolyzes beta(1-4) glycosidic bonds linking 2-acetoamido-2-deoxy-beta-D-glucopyranose units in chitin. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAC55717.1 | 0 | 1 | 297 | 1 | 297 | putative class III acidic chitinase [Oryza sativa Japonica Group] |
| GenBank | EAZ03535.1 | 0 | 1 | 297 | 1 | 297 | hypothetical protein OsI_25670 [Oryza sativa Indica Group] |
| RefSeq | XP_002461854.1 | 0 | 1 | 297 | 1 | 297 | hypothetical protein SORBIDRAFT_02g009360 [Sorghum bicolor] |
| RefSeq | XP_002461855.1 | 0 | 1 | 297 | 1 | 297 | hypothetical protein SORBIDRAFT_02g009370 [Sorghum bicolor] |
| RefSeq | XP_002461856.1 | 0 | 1 | 297 | 1 | 297 | hypothetical protein SORBIDRAFT_02g009380 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2hvm_A | 0 | 26 | 297 | 1 | 273 | A Chain A, Hevamine Mutant D125aE127A IN COMPLEX WITH TETRA-Nag |
| PDB | 1llo_A | 0 | 26 | 297 | 1 | 273 | A Chain A, Hevamine Mutant D125aE127A IN COMPLEX WITH TETRA-Nag |
| PDB | 1hvq_A | 0 | 26 | 297 | 1 | 273 | A Chain A, Crystal Structures Of Hevamine, A Plant Defence Protein With Chitinase And Lysozyme Activity, And Its Complex With An Inhibitor |
| PDB | 1kr0_A | 0 | 26 | 297 | 1 | 273 | A Chain A, Hevamine Mutant D125aY183F IN COMPLEX WITH TETRA-Nag |
| PDB | 1kr1_A | 0 | 26 | 297 | 1 | 273 | A Chain A, Hevamine Mutant D125aE127A IN COMPLEX WITH TETRA-Nag |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| chitin degradation II | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12623 | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12624 | EC-3.2.1.14 | chitinase |
| chitin degradation III (carnivorous plants) | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
