| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb02g019400.1 |
| Family | GT4 |
| Protein Properties | Length: 501 Molecular Weight: 55208.1 Isoelectric Point: 6.0038 |
| Chromosome | Chromosome/Scaffold: 2 Start: 46938005 End: 46939863 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT4 | 282 | 462 | 7.8e-22 |
| KHKGFVFLSVFKWEQRKGWDVLLRGFLQEFSGADDVVLYLLINAYHSDTNFSEKIRRFVVESSIEEPMEGWAEIRVIDEHVPQSVLPSLYKGANAFVLPT RGEGWGRPVVEAMAMELPVIVTNWSGPTEYLTEENGYPLDVDRLTEVTEGPFKGHLCAEPSIDRLRDLMRHVVDDRDEARN | |||
| Full Sequence |
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| Protein Sequence Length: 501 Download |
| MPGPGSAPTQ TPPPEPKPKH KGRRLVLLLG PPLVAVAVAL LLGVSTNPLP RRFLRLLLGT 60 KPSILSSSSP PDAAYEADAA TGAVRAPCVL WMAPFASGGG YCSEAWSYVD ALDAHAAGKS 120 NFTLAIAHHG DLDSPEFWLG LPERSKHLAY RLASERCELA RAVVVCHSEP GAWYPPMYEA 180 LPCPPTGYDD PAFVIGRTMF ETDRVCPEHV RRCNQMDAVW VPTDFHVSTF VKSGVDPTKV 240 VKVVQAVDVN FFDPAKHVAL ALPIGVSVMV PDGSRFGNGD SKHKGFVFLS VFKWEQRKGW 300 DVLLRGFLQE FSGADDVVLY LLINAYHSDT NFSEKIRRFV VESSIEEPME GWAEIRVIDE 360 HVPQSVLPSL YKGANAFVLP TRGEGWGRPV VEAMAMELPV IVTNWSGPTE YLTEENGYPL 420 DVDRLTEVTE GPFKGHLCAE PSIDRLRDLM RHVVDDRDEA RNKGKKARED MIERFSPEVV 480 ARIVAEKIQQ VLTHTQLTND * 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd03808 | GT1_cap1E_like | 2.0e-14 | 342 | 486 | 146 | + This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides. | ||
| pfam00534 | Glycos_transf_1 | 8.0e-16 | 361 | 470 | 111 | + Glycosyl transferases group 1. Mutations in this domain of human PIGA lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family. | ||
| cd03801 | GT1_YqgM_like | 2.0e-18 | 282 | 482 | 210 | + This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea. | ||
| cd03798 | GT1_wlbH_like | 2.0e-18 | 272 | 491 | 229 | + This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS. | ||
| COG0438 | RfaG | 2.0e-19 | 251 | 492 | 242 | + Glycosyltransferase [Cell envelope biogenesis, outer membrane] | ||
| Gene Ontology | |
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| GO Term | Description |
| GO:0009058 | biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACG32958.1 | 0 | 100 | 500 | 13 | 417 | glycosyl transferase, group 1 [Zea mays] |
| GenBank | EEC84295.1 | 0 | 59 | 495 | 53 | 488 | hypothetical protein OsI_30774 [Oryza sativa Indica Group] |
| RefSeq | NP_001062800.1 | 0 | 59 | 495 | 52 | 487 | Os09g0296700 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001137122.1 | 0 | 1 | 500 | 1 | 499 | hypothetical protein LOC100217302 [Zea mays] |
| RefSeq | XP_002462114.1 | 0 | 1 | 500 | 1 | 500 | hypothetical protein SORBIDRAFT_02g019400 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2bfw_A | 0.004 | 286 | 448 | 39 | 190 | A Chain A, Structure Of The C Domain Of Glycogen Synthase From Pyrococcus Abyssi |
| PDB | 3l01_B | 0.008 | 239 | 448 | 213 | 405 | A Chain A, Crystal Structure Of Monomeric Glycogen Synthase From Pyrococcus Abyssi |
| PDB | 3l01_A | 0.008 | 239 | 448 | 213 | 405 | A Chain A, Crystal Structure Of Monomeric Glycogen Synthase From Pyrococcus Abyssi |
| PDB | 2bis_C | 0.008 | 239 | 448 | 214 | 406 | A Chain A, Structure Of Glycogen Synthase From Pyrococcus Abyssi |
| PDB | 2bis_B | 0.008 | 239 | 448 | 214 | 406 | A Chain A, Structure Of Glycogen Synthase From Pyrococcus Abyssi |
| Transmembrane Domains | ||||
|---|---|---|---|---|
| Start | End | |||
| 25 | 47 | |||
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| DR967694 | 252 | 59 | 306 | 0 |
| CJ688631 | 234 | 175 | 408 | 0 |
| GT808820 | 214 | 280 | 493 | 0 |
| HO456398 | 381 | 90 | 464 | 0 |
| EG374744 | 214 | 116 | 328 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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