| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb02g023610.1 |
| Family | GT20 |
| Protein Properties | Length: 862 Molecular Weight: 97518.6 Isoelectric Point: 6.6133 |
| Chromosome | Chromosome/Scaffold: 2 Start: 57412137 End: 57419063 |
| Description | trehalose-phosphatase/synthase 9 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 56 | 544 | 0 |
| FKRKIIVANFLPMICAKNEATGEWSFAMDDNQLLVQLKDGFPIDNEVIYVGSLNVQVDPSEQDRVSQKLFKEHRCIPTFLPADLQQQFYHIFCKQHLWPL FHYMLPVCHDKGELFDRSLFQAYVRANKIFADKVVEAVNSDDDCVWVHDYHLMLIPTFLRKKLHRIKVGFFLHSPFPSSEIYRTLPVRDEILKSLLNADL IGFQTFDYARHFLSCCSRLLGLNYESKRGHIGIEYFGRTVSLKILAAGVHVGRLESMLKLPATINKVQEIESRYSGKLVILGVDDMDIFKGISLKLLGLE LLLERTPKLRGKVVLVQIVNPARSIGKDVEEAKYEAVSVAQRINDKYGSANYKPVVLIDYSIPFYEKIAFYAASDCCIVNAVRDGMNLIPYEYTVCRQGN EDIDKLRGVNKSSSHTSTLIVSEFVGCSPSLSGAFRVNPWSMEDVADALYNATDLTQYEKNLRHEKHYRYVRSHDVAYWAHSFDQDLER | |||
| Full Sequence |
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| Protein Sequence Length: 862 Download |
| MVLKSYTNLL DMCCEDVFQQ PLRSLPHVVT SPGIISDPDC ESSNDGNLVG STHICFKRKI 60 IVANFLPMIC AKNEATGEWS FAMDDNQLLV QLKDGFPIDN EVIYVGSLNV QVDPSEQDRV 120 SQKLFKEHRC IPTFLPADLQ QQFYHIFCKQ HLWPLFHYML PVCHDKGELF DRSLFQAYVR 180 ANKIFADKVV EAVNSDDDCV WVHDYHLMLI PTFLRKKLHR IKVGFFLHSP FPSSEIYRTL 240 PVRDEILKSL LNADLIGFQT FDYARHFLSC CSRLLGLNYE SKRGHIGIEY FGRTVSLKIL 300 AAGVHVGRLE SMLKLPATIN KVQEIESRYS GKLVILGVDD MDIFKGISLK LLGLELLLER 360 TPKLRGKVVL VQIVNPARSI GKDVEEAKYE AVSVAQRIND KYGSANYKPV VLIDYSIPFY 420 EKIAFYAASD CCIVNAVRDG MNLIPYEYTV CRQGNEDIDK LRGVNKSSSH TSTLIVSEFV 480 GCSPSLSGAF RVNPWSMEDV ADALYNATDL TQYEKNLRHE KHYRYVRSHD VAYWAHSFDQ 540 DLERACREQY SQRCWTTGFG LNFRIIALSP GFRRLSLEHL TSSYKKANRR MIFLDYDGTL 600 VPQASHDKSP SAELISILNS LCNDMKNTVF IVSGRGRDSL SEWFVSCENL GIAAEHGYFI 660 RWNKAAEWET SLSGLHSEWK LIVEPIMHLY METTDGSFIE QKESALVWHY QNTDHDFGLC 720 QAKELVGHLE RVLSNEPVAV RRGHQIVEVK PQGVNKGISV DKIIQTMVSK GDVPDLLMCI 780 GNDRSDEDMF ESINKATSLS EPAIPEVFAC SVGPKASKAN YYVDGCSEVI RLLKGVTAIS 840 PQKDTVSHSH AVFKDTLEVI S* 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03063 | PLN03063 | 3.0e-155 | 58 | 834 | 813 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| cd03788 | GT1_TPS | 1.0e-176 | 60 | 543 | 484 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| PLN02205 | PLN02205 | 0 | 1 | 842 | 852 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| pfam00982 | Glyco_transf_20 | 0 | 57 | 544 | 492 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| PRK14501 | PRK14501 | 0 | 57 | 839 | 806 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACG24200.1 | 0 | 1 | 861 | 1 | 864 | trehalose 6-phosphate synthase [Zea mays] |
| GenBank | ACN34016.1 | 0 | 1 | 861 | 1 | 864 | unknown [Zea mays] |
| RefSeq | NP_001061805.1 | 0 | 1 | 860 | 1 | 861 | Os08g0414700 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002445486.1 | 0 | 1 | 860 | 1 | 864 | hypothetical protein SORBIDRAFT_07g020270 [Sorghum bicolor] |
| RefSeq | XP_002462305.1 | 0 | 1 | 861 | 1 | 861 | hypothetical protein SORBIDRAFT_02g023610 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1gz5_D | 0 | 142 | 544 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_C | 0 | 142 | 544 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_B | 0 | 142 | 544 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_A | 0 | 142 | 544 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 2wtx_D | 0 | 142 | 544 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO777775 | 780 | 79 | 852 | 0 |
| HO779327 | 513 | 99 | 611 | 0 |
| HO779327 | 258 | 606 | 861 | 0 |
| HO797286 | 476 | 375 | 850 | 0 |
| HO795560 | 426 | 420 | 842 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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