| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb02g024140.1 |
| Family | GT20 |
| Protein Properties | Length: 864 Molecular Weight: 97616.8 Isoelectric Point: 6.3264 |
| Chromosome | Chromosome/Scaffold: 2 Start: 58285506 End: 58288556 |
| Description | UDP-Glycosyltransferase / trehalose-phosphatase family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 47 | 548 | 0 |
| SSHAPRERVIIVANQLPVRASRRAAGGGGWDFAWDQDSLLLQVKDSLRAHHGRADMEFVYVGGLRDDVPPAEHDEVAHELLEGFGCVPTFLPADLRSRFY HGFCKQQLWPLFHYMLPLSPELGGRFDRLLWQAYVSVNKIFADKILEVISPDEDFVWVHDYHLMVLPTFLRKRFNRVKLGFFLHSPFPSSEIYKTLPVRE ELLRSLLNADLIGFHTFDYARHFLSCCSRMLGLKYESQRGYIALEYYGRTVTIKILPVGVHLEQLQSVLNLPELGVKVGELLKQFRHRNRLLLLGVDDMD IFKGISLKLLAFEQLLMQHPEWRGRVVLVQIANPARGRGKDVKEVQEESDAMVKRINDAFGQPDYQPVILIDKPLQFYERMAYYVVAECCLVTAVRDGMN LIPYEYIIARQGNEKIDSILGLGPASRKKSMLVVSEFIGCSPSLSGAIRVNPWNIDSVADAMDYALEMPEGEKVLRHEKHHRYVSTHDVGYWANSFLQDL ER | |||
| Full Sequence |
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| Protein Sequence Length: 864 Download |
| MVSRSYSNLL ERRRIPRVVT ASGIVPDLDV SDDDADADAA SAASDHSSHA PRERVIIVAN 60 QLPVRASRRA AGGGGWDFAW DQDSLLLQVK DSLRAHHGRA DMEFVYVGGL RDDVPPAEHD 120 EVAHELLEGF GCVPTFLPAD LRSRFYHGFC KQQLWPLFHY MLPLSPELGG RFDRLLWQAY 180 VSVNKIFADK ILEVISPDED FVWVHDYHLM VLPTFLRKRF NRVKLGFFLH SPFPSSEIYK 240 TLPVREELLR SLLNADLIGF HTFDYARHFL SCCSRMLGLK YESQRGYIAL EYYGRTVTIK 300 ILPVGVHLEQ LQSVLNLPEL GVKVGELLKQ FRHRNRLLLL GVDDMDIFKG ISLKLLAFEQ 360 LLMQHPEWRG RVVLVQIANP ARGRGKDVKE VQEESDAMVK RINDAFGQPD YQPVILIDKP 420 LQFYERMAYY VVAECCLVTA VRDGMNLIPY EYIIARQGNE KIDSILGLGP ASRKKSMLVV 480 SEFIGCSPSL SGAIRVNPWN IDSVADAMDY ALEMPEGEKV LRHEKHHRYV STHDVGYWAN 540 SFLQDLERIC LDHNRRRCWG IGFGLKFRVV ALDPNFKKLA VEHLVSAYRR TTKRVILLDY 600 DGTLMPQTSF GKSPTSRTIE VLNSLCRDKN NMVFLVSAKS RMTLNEWFLP CESLGLAAEH 660 GYFLRLRRDA EWETACVPAI DCSWKQIAEP VMKTYTETTD GSTIENKETA IVWCYEDADP 720 DFGSCQAKEL HEHLESVLSN EPVSVKAGPN LVEVKPQGVS KGLVAKRILS TMQERGDLPD 780 FVLCVGDDRS DEDMFEVITT AARGVSLQAE AEVFACTVGR KPSKAKYYLD DPADIVRLVQ 840 GLANVSDDDQ THAPPLPTDT VPR* 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03063 | PLN03063 | 4.0e-162 | 52 | 847 | 834 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN02205 | PLN02205 | 0 | 1 | 847 | 859 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| pfam00982 | Glyco_transf_20 | 0 | 53 | 548 | 499 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| PRK14501 | PRK14501 | 0 | 54 | 845 | 806 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| cd03788 | GT1_TPS | 0 | 54 | 547 | 494 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EEC84539.1 | 0 | 1 | 860 | 1 | 879 | hypothetical protein OsI_31278 [Oryza sativa Indica Group] |
| RefSeq | NP_001063104.1 | 0 | 1 | 860 | 1 | 860 | Os09g0397300 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002284972.1 | 0 | 1 | 847 | 1 | 849 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002314777.1 | 0 | 1 | 847 | 1 | 835 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002460185.1 | 0 | 1 | 863 | 1 | 863 | hypothetical protein SORBIDRAFT_02g024140 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2wtx_D | 0 | 145 | 550 | 76 | 455 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_C | 0 | 145 | 550 | 76 | 455 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_B | 0 | 145 | 550 | 76 | 455 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_A | 0 | 145 | 550 | 76 | 455 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 1gz5_D | 0 | 145 | 550 | 75 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO777775 | 773 | 76 | 847 | 0 |
| HO779327 | 516 | 100 | 615 | 0 |
| HO779327 | 243 | 610 | 852 | 0 |
| HO797286 | 481 | 378 | 858 | 0 |
| HO777775 | 76 | 1 | 64 | 5.8 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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