| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb02g030220.1 |
| Family | GH29 |
| Protein Properties | Length: 487 Molecular Weight: 53471.1 Isoelectric Point: 6.4519 |
| Chromosome | Chromosome/Scaffold: 2 Start: 65307963 End: 65310024 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH29 | 41 | 340 | 0 |
| APQLKWQRREVIMFFHFGMNTFTDSEWGTGSEAPSLFRPAALNATQWMDAARAAGASLAILVAKHHDGFCLWPSQYTAHSVRASPWRGGRGDVVREFVDA ARARGVDAGLYLSPWDRHDERYGNEVAYNEYYEAQLHELLTGYGSVSEIWFDGAKGKNATNMTYHFQEWFQTVKQLQRSINIFSDDGPDVRWVGDEKGYA GTTCWSTVNRSMITIGEAGIEKYLNEGDPRGRDWVPPECDVSIRPGWFWHKNETAKPLSQLLEIYYNSVGRNCVLLLNAPPNTTGLVQDADIARLREFGA | |||
| Full Sequence |
|---|
| Protein Sequence Length: 487 Download |
| MASSLLCLAA LAVVSVLVTT TEALPPRATP PPLPVLPIPS APQLKWQRRE VIMFFHFGMN 60 TFTDSEWGTG SEAPSLFRPA ALNATQWMDA ARAAGASLAI LVAKHHDGFC LWPSQYTAHS 120 VRASPWRGGR GDVVREFVDA ARARGVDAGL YLSPWDRHDE RYGNEVAYNE YYEAQLHELL 180 TGYGSVSEIW FDGAKGKNAT NMTYHFQEWF QTVKQLQRSI NIFSDDGPDV RWVGDEKGYA 240 GTTCWSTVNR SMITIGEAGI EKYLNEGDPR GRDWVPPECD VSIRPGWFWH KNETAKPLSQ 300 LLEIYYNSVG RNCVLLLNAP PNTTGLVQDA DIARLREFGA AVSTIFGTDL AAGSEARASS 360 ERGAGFAARN VVDGRDDTYW APAPATAGED DGYYWIELRR PGARAFNVVR IQEHVALGQR 420 VERHAVYVDG APVANGTTVG HKRLHRLPSA VVAGTTVRVW IEARRGPPLL SAVGLHYDPF 480 AAADTM* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01120 | Alpha_L_fucos | 3.0e-22 | 53 | 340 | 322 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 1.0e-25 | 76 | 349 | 298 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| COG3669 | COG3669 | 1.0e-51 | 43 | 350 | 318 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| GO:0007155 | cell adhesion |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACR35251.1 | 0 | 1 | 486 | 1 | 485 | unknown [Zea mays] |
| GenBank | EEC84898.1 | 0 | 41 | 482 | 45 | 489 | hypothetical protein OsI_32076 [Oryza sativa Indica Group] |
| RefSeq | NP_001063703.1 | 0 | 41 | 482 | 45 | 489 | Os09g0520800 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001151568.1 | 0 | 1 | 486 | 1 | 485 | alpha-L-fucosidase 1 [Zea mays] |
| RefSeq | XP_002462685.1 | 0 | 1 | 486 | 1 | 486 | hypothetical protein SORBIDRAFT_02g030220 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3ues_B | 0 | 39 | 471 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 39 | 471 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3mo4_B | 0 | 39 | 471 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3mo4_A | 0 | 39 | 471 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3eyp_B | 0 | 34 | 476 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
