| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb02g036640.1 |
| Family | GT47 |
| Protein Properties | Length: 501 Molecular Weight: 55798.1 Isoelectric Point: 9.6977 |
| Chromosome | Chromosome/Scaffold: 2 Start: 71036574 End: 71042475 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 103 | 423 | 0 |
| PVKIYLYDLPAKFTYGVVRSYTATRAPSGSADAAAALPDEQLRYPGHQHSAEWWLFKDLLRRGPRDRPVARVDDPSDADLFYVPFFSSLSLVVNPIRSPP AANASGAAAAYSDDAMQEELLEWLERQPYWRRHMGRDHVFICQDPNALYRVIDRISNAVLLVSDFGRLRSDQASLVKDVILPYSHRINSFKGEVGVDGRP LLLFFMGNRYRKEGGKVRDALFQILENEDDVTIKHGTQSRESRRAARQGMHSSKFCLHPAGDTPSACRLFDALVSLCVPVIVSDYIELPFEDIIDYNKIS IFVGTSKAVQPGYLTSMLRRI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 501 Download |
| MWERGRPPRK PRPSPILVPP PPSSPPPRLN LLLPRSLLAL AARAMPSRRS SPVLLLLLAL 60 SLALLFLLLS PSSPSASRFS HSLSSGSVIA YSSPASTSAP PAPVKIYLYD LPAKFTYGVV 120 RSYTATRAPS GSADAAAALP DEQLRYPGHQ HSAEWWLFKD LLRRGPRDRP VARVDDPSDA 180 DLFYVPFFSS LSLVVNPIRS PPAANASGAA AAYSDDAMQE ELLEWLERQP YWRRHMGRDH 240 VFICQDPNAL YRVIDRISNA VLLVSDFGRL RSDQASLVKD VILPYSHRIN SFKGEVGVDG 300 RPLLLFFMGN RYRKEGGKVR DALFQILENE DDVTIKHGTQ SRESRRAARQ GMHSSKFCLH 360 PAGDTPSACR LFDALVSLCV PVIVSDYIEL PFEDIIDYNK ISIFVGTSKA VQPGYLTSML 420 RRISSERILE YQRETKKVKR YFEYEDPNGP VNEIWRQVSL KAPLIKLLIN RNKRLLERGT 480 NGTDCSCICS TTPTEITAAS * 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-70 | 104 | 423 | 331 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACG27631.1 | 0 | 104 | 500 | 60 | 456 | exostosin-like [Zea mays] |
| GenBank | ACN31783.1 | 0 | 104 | 500 | 104 | 500 | unknown [Zea mays] |
| GenBank | EEE67431.1 | 0 | 1 | 492 | 1 | 494 | hypothetical protein OsJ_24780 [Oryza sativa Japonica Group] |
| RefSeq | NP_001060019.1 | 0 | 1 | 492 | 1 | 494 | Os07g0567000 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002460871.1 | 0 | 43 | 500 | 43 | 500 | hypothetical protein SORBIDRAFT_02g036640 [Sorghum bicolor] |
