| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb02g037060.1 |
| Family | GT68 |
| Protein Properties | Length: 563 Molecular Weight: 62369.7 Isoelectric Point: 7.5154 |
| Chromosome | Chromosome/Scaffold: 2 Start: 71461053 End: 71466075 |
| Description | O-fucosyltransferase family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT68 | 246 | 539 | 0 |
| TLVVPSQKVDYQYDRVLDINHINDCIGRKVVITYEEFVEKRKKVVIDQFICYAASPPCFLDEDHIKKLKGLGISLGKIEAAWPEDAKLKEPKKRFVGDIT PKFSTEAEVLAIGDMFYADMEDEWLNQPGGPLAHKCKTLIQPSRLIMLTAQRFVQTFLGGNYIALHFRRHGFLKFCNVKKESCFFPIPQAAECILRIVEK ANAPVIYLSTDAAESETNLLQSLVVFNDRQVPLVKRPEHDSSEKWDALLHRNHIGGDVQVDAMLDKTICALSNVFIGSSGSTFTEDIFRLRRGW | |||
| Full Sequence |
|---|
| Protein Sequence Length: 563 Download |
| MDRGPSVSDD EDDLETLVPQ NHAKPPSPSA RSRSPPSSFS VAALHPALPS SAASLGRILW 60 SRRYLVLFVS LPLLFLILFV SFGGASSIRL PASIRLPSAA PAADPAASRM REAELHALYL 120 LRSQRSGLLS LFNRTAAPTN GSASAPISLS DLQSALESQI KINREIQAAL LSSHRSGTGN 180 ATEDGLDLDL PFSGCRKREL PANRRTIEWN PKKDRFLLAI CISGQMSNHL ICLEKHMFMA 240 ALLGRTLVVP SQKVDYQYDR VLDINHINDC IGRKVVITYE EFVEKRKKVV IDQFICYAAS 300 PPCFLDEDHI KKLKGLGISL GKIEAAWPED AKLKEPKKRF VGDITPKFST EAEVLAIGDM 360 FYADMEDEWL NQPGGPLAHK CKTLIQPSRL IMLTAQRFVQ TFLGGNYIAL HFRRHGFLKF 420 CNVKKESCFF PIPQAAECIL RIVEKANAPV IYLSTDAAES ETNLLQSLVV FNDRQVPLVK 480 RPEHDSSEKW DALLHRNHIG GDVQVDAMLD KTICALSNVF IGSSGSTFTE DIFRLRRGWG 540 SASHCDEYLC QGELPNYIAE VD* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd11296 | O-FucT_like | 4.0e-5 | 216 | 259 | 44 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11548 | NodZ_like | 8.0e-6 | 382 | 530 | 159 | + Alpha 1,6-fucosyltransferase similar to Bradyrhizobium NodZ. Bradyrhizobium NodZ is an alpha 1,6-fucosyltransferase involved in the biosynthesis of the nodulation factor, a lipo-chitooligosaccharide formed by three-to-six beta-1,4-linked N-acetyl-d-glucosamine (GlcNAc) residues and a fatty acid acyl group attached to the nitrogen atom at the non-reducing end. NodZ transfers L-fucose from the GDP-beta-L-fucose donor to the reducing residue of the chitin oligosaccharide backbone, before the attachment of a fatty acid group. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| pfam10250 | O-FucT | 2.0e-7 | 240 | 537 | 326 | + GDP-fucose protein O-fucosyltransferase. This is a family of conserved proteins representing the enzyme responsible for adding O-fucose to EGF (epidermal growth factor-like) repeats. Six highly conserved cysteines are present in O-FucT-1 as well as a DXD-like motif (ERD), conserved in mammals, Drosophila, and C. elegans. Both features are characteristic of several glycosyltransferase families. The enzyme is a membrane-bound protein released by proteolysis and, as for most glycosyltransferases, is strongly activated by manganese. | ||
| cd11298 | O-FucT-2 | 4.0e-11 | 389 | 536 | 148 | + GDP-fucose protein O-fucosyltransferase 2. O-FucT-2 adds O-fucose to thrombospondin type 1 repeats (TSRs), and appears conserved in bilateria. The O-fucosylation of TSRs appears to play a role in regulating secretion of metalloproteases of the ADAMTS superfamily. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11296 | O-FucT_like | 6.0e-18 | 377 | 537 | 171 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_001060060.1 | 0 | 1 | 562 | 1 | 557 | Os07g0572600 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_173170.2 | 0 | 8 | 560 | 6 | 562 | unknown protein [Arabidopsis thaliana] |
| RefSeq | XP_002264087.1 | 0 | 8 | 560 | 6 | 557 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002303337.1 | 0 | 102 | 560 | 62 | 525 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002460894.1 | 0 | 1 | 562 | 1 | 562 | hypothetical protein SORBIDRAFT_02g037060 [Sorghum bicolor] |
