| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb03g008610.1 |
| Family | GT47 |
| Protein Properties | Length: 522 Molecular Weight: 59074 Isoelectric Point: 9.4134 |
| Chromosome | Chromosome/Scaffold: 3 Start: 9205995 End: 9208984 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 188 | 474 | 0 |
| RLLKVFIYHDGAKPIFHSPELKGIYASEGWFMRLMETNQNFVVRDPNRAHLFYLPYSSRQLEHNLYVPGSNSIEPLSIFVKNYIDLISAKYPYWNRTKGA DHFFVACHDWGPYTTKLHDELRKNTIKALCNADLSEGIFIRGKDVSLPETFLRSPRRPLRDIGGRPAAQRTILAFFAGQMHGRVRPVLLKYWGDKDADMR IYSRLPHRITRKRNYVQHMKSSKYCICPMGYEVNSPRIVEAIYYECVPVIIADNFVLPFDAALNWSAFSVVVPESDVPKLKEILLAI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 522 Download |
| MPHHHHTNPS HPPAARKLLS WRRVVAACAA VAALVLLLAA APATEDPSRW RSYLMGPLPG 60 GTRKETVAAA VVARSFAGPA ASTSSPAEAP LSSLGEINLS ARIAPAAAPS MFLVPSSSPT 120 ENFDDGSMEE PEHPEIKAPL WSTAADEELI YAKKEITNTP LTSDDPDLYA PLFRNVSIFK 180 RSYELMERLL KVFIYHDGAK PIFHSPELKG IYASEGWFMR LMETNQNFVV RDPNRAHLFY 240 LPYSSRQLEH NLYVPGSNSI EPLSIFVKNY IDLISAKYPY WNRTKGADHF FVACHDWGPY 300 TTKLHDELRK NTIKALCNAD LSEGIFIRGK DVSLPETFLR SPRRPLRDIG GRPAAQRTIL 360 AFFAGQMHGR VRPVLLKYWG DKDADMRIYS RLPHRITRKR NYVQHMKSSK YCICPMGYEV 420 NSPRIVEAIY YECVPVIIAD NFVLPFDAAL NWSAFSVVVP ESDVPKLKEI LLAIPESRYI 480 TLQSNVKRVQ KHFLWHPNPV KYDIFHMILH SVWFSRVNQI R* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-66 | 186 | 474 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI23466.1 | 0 | 140 | 521 | 153 | 534 | unnamed protein product [Vitis vinifera] |
| GenBank | EEC69788.1 | 0 | 42 | 521 | 37 | 534 | hypothetical protein OsI_00072 [Oryza sativa Indica Group] |
| RefSeq | NP_001041784.1 | 0 | 42 | 521 | 37 | 548 | Os01g0107700 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002269459.1 | 0 | 140 | 521 | 153 | 534 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002457517.1 | 0 | 1 | 521 | 1 | 521 | hypothetical protein SORBIDRAFT_03g008610 [Sorghum bicolor] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
