| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb03g013610.1 |
| Family | GH19 |
| Protein Properties | Length: 280 Molecular Weight: 30078.8 Isoelectric Point: 5.8738 |
| Chromosome | Chromosome/Scaffold: 3 Start: 17174397 End: 17175725 |
| Description | homolog of carrot EP3-3 chitinase |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH19 | 83 | 279 | 0 |
| VVTESFNGIKSQAGSWCEGIGFYTRSVFLEAVAAYPGFAHGGSEVEIKREIAAFFAHVTHETGNLCYINEVDVAKYCDWKSEKQWPCYPGQGYYGRGPLQ LSWNYNYGPAGRSLGFDGLRDPDRLAQDPVLSFKSALWYWMENVHQLMPHGFGATIRAINGDECHDGKNTAEMEDRVRLYLEYCHYFGIDPGSDLTC | |||
| Full Sequence |
|---|
| Protein Sequence Length: 280 Download |
| MANSPTPPAA MIPTAVLALG LAILICAGRP TAAQNCGCQP GFCCSKFGYC GKTSDYCGEG 60 CKSGPCWGSG SGGGRGGASV ASVVTESFNG IKSQAGSWCE GIGFYTRSVF LEAVAAYPGF 120 AHGGSEVEIK REIAAFFAHV THETGNLCYI NEVDVAKYCD WKSEKQWPCY PGQGYYGRGP 180 LQLSWNYNYG PAGRSLGFDG LRDPDRLAQD PVLSFKSALW YWMENVHQLM PHGFGATIRA 240 INGDECHDGK NTAEMEDRVR LYLEYCHYFG IDPGSDLTC* 300 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| smart00270 | ChtBD1 | 6.0e-7 | 38 | 64 | 27 | + Chitin binding domain. | ||
| COG3179 | COG3179 | 2.0e-7 | 111 | 262 | 188 | + Predicted chitinase [General function prediction only] | ||
| cd00442 | lysozyme_like | 7.0e-9 | 162 | 224 | 63 | + lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases. All the members are involved in the hydrolysis of beta-1,4- linked polysaccharides. | ||
| pfam00182 | Glyco_hydro_19 | 4.0e-74 | 88 | 279 | 226 | + Chitinase class I. | ||
| cd00325 | chitinase_glyco_hydro_19 | 4.0e-84 | 88 | 279 | 226 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004568 | chitinase activity |
| GO:0006032 | chitin catabolic process |
| GO:0008061 | chitin binding |
| GO:0016998 | cell wall macromolecule catabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACJ61992.1 | 0 | 1 | 279 | 1 | 280 | chitinase [Zea mays subsp. parviglumis] |
| GenBank | ACJ61994.1 | 0 | 1 | 279 | 1 | 280 | chitinase [Zea mays subsp. parviglumis] |
| GenBank | ACJ61997.1 | 0 | 1 | 279 | 1 | 280 | chitinase [Zea mays subsp. parviglumis] |
| RefSeq | XP_002448105.1 | 0 | 30 | 279 | 24 | 271 | hypothetical protein SORBIDRAFT_06g021220 [Sorghum bicolor] |
| RefSeq | XP_002455593.1 | 0 | 1 | 279 | 1 | 279 | hypothetical protein SORBIDRAFT_03g013610 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3hbh_A | 0 | 79 | 279 | 1 | 204 | A Chain A, Crystal Structure Of The Polygalacturonase From Colletotrichum Lupini And Its Implications For The Interaction With Polygalacturonase- Inhibiting Proteins |
| PDB | 3hbe_X | 0 | 79 | 279 | 1 | 204 | A Chain A, Crystal Structure Of The Polygalacturonase From Colletotrichum Lupini And Its Implications For The Interaction With Polygalacturonase- Inhibiting Proteins |
| PDB | 3hbd_A | 0 | 79 | 279 | 1 | 204 | A Chain A, Class Iv Chitinase Structure From Picea Abies At 1.8a |
| PDB | 2z37_D | 0 | 88 | 279 | 12 | 237 | A Chain A, Crystal Structure Of Brassica Juncea Chitinase Catalytic Module (Bjchi3) |
| PDB | 2z37_C | 0 | 88 | 279 | 12 | 237 | A Chain A, Crystal Structure Of Brassica Juncea Chitinase Catalytic Module (Bjchi3) |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| chitin degradation II | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12623 | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12624 | EC-3.2.1.14 | chitinase |
| chitin degradation III (carnivorous plants) | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
