| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb03g015470.1 |
| Family | GT28 |
| Protein Properties | Length: 440 Molecular Weight: 46586.7 Isoelectric Point: 7.1033 |
| Chromosome | Chromosome/Scaffold: 3 Start: 23687038 End: 23695753 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT28 | 262 | 421 | 7.14662e-44 |
| VLVLGGAEGSPEINVAVLNVYYEILRSKDRYIIWQTGTETFCEMESLVRGHRRLFLTPFLHELEMAYAASDVVISRAGAMTCTEILATGKPSILIPLPTI LDHHQTRNAYIMADIMGAKVITEDELDSSSLTSAVDEIFGDEKLMADMSQKALTAARPNA | |||
| Full Sequence |
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| Protein Sequence Length: 440 Download |
| MAATAAQPGP LPPAIRFGST QTSNLAIPTR TAPAPARLRC HLSHSSDSTP TPTSPALTTS 60 DPDRDPDHES ESESEGILRF AFACGGAGAG GRVYSAIALA DELHASLPSS RSLILGAPAP 120 SLESSAAAAA SYPFAPVPLR CLPGGILAAA LHLCRFRPHV LVATGGAPAL PACLAALMLR 180 LPFVIQDQDA SPAPATRLLA PFARRVFLAF NAPVRLLPKR RCAVYGNPIR MSILKCSASK 240 IEALARFFPR AGLLGEHDAQ VVLVLGGAEG SPEINVAVLN VYYEILRSKD RYIIWQTGTE 300 TFCEMESLVR GHRRLFLTPF LHELEMAYAA SDVVISRAGA MTCTEILATG KPSILIPLPT 360 ILDHHQTRNA YIMADIMGAK VITEDELDSS SLTSAVDEIF GDEKLMADMS QKALTAARPN 420 ASADIIRHIC SLIGSPYPS* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam04101 | Glyco_tran_28_C | 1.0e-26 | 261 | 425 | 170 | + Glycosyltransferase family 28 C-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site. | ||
| TIGR01133 | murG | 1.0e-47 | 138 | 426 | 290 | + undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]. | ||
| COG0707 | MurG | 6.0e-48 | 145 | 426 | 282 | + UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell envelope biogenesis, outer membrane] | ||
| PRK00726 | murG | 2.0e-62 | 145 | 435 | 291 | + undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional | ||
| cd03785 | GT1_MurG | 2.0e-78 | 142 | 428 | 288 | + MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005975 | carbohydrate metabolic process |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| GO:0030246 | carbohydrate binding |
| GO:0030259 | lipid glycosylation |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EAY74292.1 | 0 | 32 | 435 | 47 | 429 | hypothetical protein OsI_02179 [Oryza sativa Indica Group] |
| GenBank | EEE54689.1 | 0 | 32 | 435 | 47 | 429 | hypothetical protein OsJ_01999 [Oryza sativa Japonica Group] |
| RefSeq | NP_001043195.1 | 0 | 32 | 435 | 47 | 429 | Os01g0516700 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001149881.1 | 0 | 1 | 439 | 1 | 444 | glycosyltransferase family 28 C-terminal domain containing protein [Zea mays] |
| RefSeq | XP_002457846.1 | 0 | 1 | 439 | 1 | 439 | hypothetical protein SORBIDRAFT_03g015470 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3s2u_A | 9e-26 | 87 | 426 | 10 | 348 | A Chain A, Crystal Structure Of The Pseudomonas Aeruginosa Murg:udp-glcnac Substrate Comp |
| PDB | 1nlm_B | 6e-21 | 87 | 432 | 14 | 353 | A Chain A, Crystal Structure Of The Pseudomonas Aeruginosa Murg:udp-glcnac Substrate Comp |
| PDB | 1nlm_A | 6e-21 | 87 | 432 | 14 | 353 | A Chain A, Crystal Structure Of The Pseudomonas Aeruginosa Murg:udp-glcnac Substrate Comp |
| PDB | 1f0k_B | 6e-21 | 87 | 432 | 14 | 353 | A Chain A, The 1.9 Angstrom Crystal Structure Of E. Coli Murg |
| PDB | 1f0k_A | 6e-21 | 87 | 432 | 14 | 353 | A Chain A, The 1.9 Angstrom Crystal Structure Of E. Coli Murg |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| CX612710 | 207 | 234 | 440 | 0 |
| CX614930 | 202 | 239 | 440 | 0 |
| CX617839 | 192 | 249 | 440 | 0 |
| FL977112 | 192 | 250 | 440 | 0 |
| JG926195 | 186 | 256 | 440 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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