| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb03g029210.1 |
| Family | GT47 |
| Protein Properties | Length: 518 Molecular Weight: 58692 Isoelectric Point: 10.3836 |
| Chromosome | Chromosome/Scaffold: 3 Start: 57346215 End: 57348233 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 180 | 467 | 0 |
| RILKVYIYQDGRRPIFHTPPLSGIYASEGWFMKLLKESRRHVVADAGKAHLFYLPYSSQQLRLTLYQADSHNLRPLAAYLRNFVRGLANKYPFWNRTRGA DHFLVACHDWGPYTTAAHRDLRKNAIKALCNADSSEGIFTPGKDVSLPETTIRNPRRPLRYVGGLPVSRRSILAFFAGNVHGRVRPVLLRHWGDGQDDEM RVYSLLPNRVSRRMNYIQHMKNSRFCLCPMGYEVNSPRIVEAFYYECVPVIIADNFVLPLSEVLDWSAFSVVVAEKDIPDLKKILQGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 518 Download |
| MRPPPHVATS PSAAYHAGSS RRRPRHRGGI GSGMTMTVSF CRVAALVSLL AAGAATALLT 60 FSLPSSPGVS TTRRTDFAGA LPVANETPPL PHLSAPATPP PAPLLPPPAV RPRKREWPEI 120 RLHVSVCDQP SYWRMAPEVA LRYAKKEIRN AEPVVDDPDL YAPLFKNVSQ FKRSYELMER 180 ILKVYIYQDG RRPIFHTPPL SGIYASEGWF MKLLKESRRH VVADAGKAHL FYLPYSSQQL 240 RLTLYQADSH NLRPLAAYLR NFVRGLANKY PFWNRTRGAD HFLVACHDWG PYTTAAHRDL 300 RKNAIKALCN ADSSEGIFTP GKDVSLPETT IRNPRRPLRY VGGLPVSRRS ILAFFAGNVH 360 GRVRPVLLRH WGDGQDDEMR VYSLLPNRVS RRMNYIQHMK NSRFCLCPMG YEVNSPRIVE 420 AFYYECVPVI IADNFVLPLS EVLDWSAFSV VVAEKDIPDL KKILQGISPR RYVAMHSCVK 480 RLQRHFLWHA RPIKYDLFHM ILHSIWLSRV NQVELEG* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-70 | 182 | 467 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EEC71161.1 | 0 | 3 | 516 | 2 | 498 | hypothetical protein OsI_03019 [Oryza sativa Indica Group] |
| GenBank | EEE55063.1 | 0 | 4 | 516 | 2 | 481 | hypothetical protein OsJ_02778 [Oryza sativa Japonica Group] |
| RefSeq | NP_001043679.1 | 0 | 3 | 516 | 2 | 500 | Os01g0640600 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002269459.1 | 0 | 133 | 515 | 154 | 535 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002456034.1 | 0 | 1 | 517 | 1 | 517 | hypothetical protein SORBIDRAFT_03g029210 [Sorghum bicolor] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
