| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb03g033590.1 |
| Family | GT20 |
| Protein Properties | Length: 892 Molecular Weight: 99891.1 Isoelectric Point: 5.5419 |
| Chromosome | Chromosome/Scaffold: 3 Start: 61845919 End: 61850880 |
| Description | trehalose-phosphatase/synthase 7 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 86 | 574 | 0 |
| FASDRLIVVANTLPVRVERGPDGRGWSFSWDEDSLLFHLRDGLPEDMEVLYVGSLRADVPAVEQDEVAQALLDSFRCVPAFLPKDLCDRFYHGFCKQTLW PLFHYMLPFSPDHGGRFDRSHWEAYVLANKLFSQRVIEVLNPEDDYVWIHDYHLLALPSFLRRRFNRLRIGFFLHSPFPSSELYRSLPVRDEILKSLLNC DLIGFHTFDYARHFLSCCSRMLGIEYQSKRGYIGLDYFGRTVGIKIMPVGINMVQLQSLLQQPDLERQVTELRHQFNRKTVLLGVDDMDIFKGIDLKILA FEQMLKTHPKWQGRAVLVQIANPKGGSGKDLEGLQTEIEDSCRRINEQFGRTGYSPVVLVNRTLSSVERMAYYTIAECVVVTAVRDGMNLTPYEYIVCRQ GIPGLAGSVDDKPRGKSMLVVSEFIGCSPSLSGAIRVNPWNIESTAEAMNESIAFSDTEKQLRHEKHYRYVSSHDVAYWSKSYIHDFER | |||
| Full Sequence |
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| Protein Sequence Length: 892 Download |
| MFSRSYTNLV DLANGNLSAL DYGGGGGAWG DGGGGGGGGG GGGAGGGGRP PRARRMQRTM 60 TTPGTLVELD DEDQAGSVAS DVPSSFASDR LIVVANTLPV RVERGPDGRG WSFSWDEDSL 120 LFHLRDGLPE DMEVLYVGSL RADVPAVEQD EVAQALLDSF RCVPAFLPKD LCDRFYHGFC 180 KQTLWPLFHY MLPFSPDHGG RFDRSHWEAY VLANKLFSQR VIEVLNPEDD YVWIHDYHLL 240 ALPSFLRRRF NRLRIGFFLH SPFPSSELYR SLPVRDEILK SLLNCDLIGF HTFDYARHFL 300 SCCSRMLGIE YQSKRGYIGL DYFGRTVGIK IMPVGINMVQ LQSLLQQPDL ERQVTELRHQ 360 FNRKTVLLGV DDMDIFKGID LKILAFEQML KTHPKWQGRA VLVQIANPKG GSGKDLEGLQ 420 TEIEDSCRRI NEQFGRTGYS PVVLVNRTLS SVERMAYYTI AECVVVTAVR DGMNLTPYEY 480 IVCRQGIPGL AGSVDDKPRG KSMLVVSEFI GCSPSLSGAI RVNPWNIEST AEAMNESIAF 540 SDTEKQLRHE KHYRYVSSHD VAYWSKSYIH DFERSCRDHF RRRCWGIGLG FGFRVVALDR 600 NFKKLNVDSI VADYKKSKSR IILLDYDGTL VPQTTMNKTP SETVVNMMNT LCADKKNVIF 660 IVSGRGRDSL EKWFYPCPEL GIAAEHGYFM RWTRDEQWQI QHQTSDFGWM HMAEPVMKLY 720 TEATDGSYIE TKESALVWHH QDADPGFGSA QAKEMLDHLE SVLANEPVSV KSGQHIVEVK 780 PQAVSKGFVA EKILSTLMDK GRQADFVLCI GDDRSDEDMF EQIADSMRRS MVDPETSLYA 840 CTVGQKPSKA IYYLDDANEV LNMLEALADA SEEAGSGSPE ATDGPSTLEE A* 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03063 | PLN03063 | 2.0e-163 | 90 | 871 | 819 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN02205 | PLN02205 | 0 | 1 | 873 | 880 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| pfam00982 | Glyco_transf_20 | 0 | 90 | 574 | 489 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| PRK14501 | PRK14501 | 0 | 90 | 870 | 786 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| cd03788 | GT1_TPS | 0 | 90 | 573 | 484 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACN33296.1 | 0 | 1 | 871 | 1 | 876 | unknown [Zea mays] |
| GenBank | EAZ13427.1 | 0 | 1 | 876 | 1 | 864 | hypothetical protein OsJ_03344 [Oryza sativa Japonica Group] |
| GenBank | EEC71425.1 | 0 | 1 | 876 | 1 | 809 | hypothetical protein OsI_03616 [Oryza sativa Indica Group] |
| RefSeq | NP_001044141.1 | 0 | 1 | 876 | 1 | 864 | Os01g0730300 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002456290.1 | 0 | 1 | 891 | 1 | 891 | hypothetical protein SORBIDRAFT_03g033590 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2wtx_D | 0 | 172 | 574 | 73 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_C | 0 | 172 | 574 | 73 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_B | 0 | 172 | 574 | 73 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_A | 0 | 172 | 574 | 73 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 1gz5_D | 0 | 172 | 574 | 72 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO777775 | 780 | 111 | 880 | 0 |
| HO779327 | 514 | 131 | 641 | 0 |
| HO779327 | 236 | 637 | 872 | 0 |
| HO795511 | 471 | 404 | 874 | 0 |
| HO777775 | 122 | 1 | 122 | 2.5 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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