| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb03g034640.1 |
| Family | GT20 |
| Protein Properties | Length: 911 Molecular Weight: 101721 Isoelectric Point: 4.9298 |
| Chromosome | Chromosome/Scaffold: 3 Start: 62806280 End: 62810877 |
| Description | trehalose-phosphatase/synthase 7 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 75 | 577 | 0 |
| AADRVIVVSNQLPIVARRRPDGRGWSFSWDDDSLLLQLRDGIPDEMEVLFVGSLRADVPVAEQDEVSQALLDRFRCAPVFLPDHLNDRFYHGFCKRQLWP LFHYMLPFSSSASAATTSSSVAPSSPGNGRFDRSAWEAYVLANKFFFEKVVEVINPEEDYVWVHDYHLMALPTFLRRRFNRLRIGFFLHSPFPSSEIYRT LPVREEILKALLNCDLIGFHTFDYARHFLSCCSRMLGIEYQSKRGYIGLDYFGRTVGIKIMPVGIHMGQLESGLRLPDREWRLSELQQQFEGRTVLLGVD DMDIFKGINLKLLAFENMLRTHPKWQGRAVLVQIANPARGRGKDLEAIQAEIEESCRRINGDFGQSGYSPVVFIDRDVSSVEKIAYYTIAECVVVTAVRD GMNLTPYEYIVSRQGAPGSESVSEVSGPKKSMLVVSEFIGCSPSLSGAIRVNPWNIEATAEAMNEAISMPEQEKQLRHEKHYRYVSSHDVAFWSRSFILD LQR | |||
| Full Sequence |
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| Protein Sequence Length: 911 Download |
| MMSRSYTNLL DLAEGNFAAL GPAGGSGRQR QGSFGMRRMS RVMTVPGTLS ELDGEDESEP 60 AATNSVASDA PSSLAADRVI VVSNQLPIVA RRRPDGRGWS FSWDDDSLLL QLRDGIPDEM 120 EVLFVGSLRA DVPVAEQDEV SQALLDRFRC APVFLPDHLN DRFYHGFCKR QLWPLFHYML 180 PFSSSASAAT TSSSVAPSSP GNGRFDRSAW EAYVLANKFF FEKVVEVINP EEDYVWVHDY 240 HLMALPTFLR RRFNRLRIGF FLHSPFPSSE IYRTLPVREE ILKALLNCDL IGFHTFDYAR 300 HFLSCCSRML GIEYQSKRGY IGLDYFGRTV GIKIMPVGIH MGQLESGLRL PDREWRLSEL 360 QQQFEGRTVL LGVDDMDIFK GINLKLLAFE NMLRTHPKWQ GRAVLVQIAN PARGRGKDLE 420 AIQAEIEESC RRINGDFGQS GYSPVVFIDR DVSSVEKIAY YTIAECVVVT AVRDGMNLTP 480 YEYIVSRQGA PGSESVSEVS GPKKSMLVVS EFIGCSPSLS GAIRVNPWNI EATAEAMNEA 540 ISMPEQEKQL RHEKHYRYVS SHDVAFWSRS FILDLQRACQ DHFKRTCWGI GLGFGFRVVA 600 LDPHFTKLNM DLIVNAYEIS ESRAILLDYD GTLVPQTSIN KEPSPEVLSI INTLCSDSRN 660 TVFLVSGRDK DTLGKWFSSC PKLGIAAEHG YFLRWSREEE WQTCTQALDF GWMQMARPVM 720 NLYTEATDGS YIETKESALV WHHQDADPGF GSSQAKEMLD HLESVLANEP VSVKSGQFIV 780 EVKPQGVTKG IVAERILASV KERGKQADFV LCIGDDRSDE DMFENIADII NRNVVDPRTS 840 LFACTVGQKP SKAKFYLDDT FEVVTMLSAL ADATGPELET DSADELAASI SSLDIGDEQS 900 ESSDRPIGGS * 960 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03063 | PLN03063 | 3.0e-171 | 78 | 873 | 832 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN02205 | PLN02205 | 0 | 1 | 874 | 881 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| pfam00982 | Glyco_transf_20 | 0 | 78 | 577 | 504 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| PRK14501 | PRK14501 | 0 | 78 | 873 | 802 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| cd03788 | GT1_TPS | 0 | 78 | 576 | 499 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACN25869.1 | 0 | 39 | 910 | 1 | 874 | unknown [Zea mays] |
| GenBank | ACN33296.1 | 0 | 1 | 910 | 1 | 912 | unknown [Zea mays] |
| GenBank | EEC71477.1 | 0 | 1 | 909 | 1 | 914 | hypothetical protein OsI_03737 [Oryza sativa Indica Group] |
| RefSeq | NP_001044248.1 | 0 | 1 | 909 | 1 | 913 | Os01g0749400 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002458490.1 | 0 | 1 | 910 | 1 | 910 | hypothetical protein SORBIDRAFT_03g034640 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1gz5_D | 0 | 161 | 577 | 73 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_C | 0 | 161 | 577 | 73 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_B | 0 | 161 | 577 | 73 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_A | 0 | 161 | 577 | 73 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 2wtx_D | 0 | 161 | 577 | 74 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO777775 | 782 | 99 | 871 | 0 |
| HO779327 | 528 | 119 | 644 | 0 |
| HO779327 | 238 | 640 | 877 | 0 |
| HO795511 | 468 | 407 | 874 | 0 |
| HO777775 | 95 | 1 | 95 | 2.3 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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