| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb03g040220.1 |
| Family | GT47 |
| Protein Properties | Length: 427 Molecular Weight: 48563.9 Isoelectric Point: 9.9101 |
| Chromosome | Chromosome/Scaffold: 3 Start: 67825961 End: 67829428 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 52 | 349 | 0 |
| DLRIYVYAEDEIQGLRALLRGRDGTITAATCLKGQWGTQVKIHQFLLKSRFRTFNKDQANLFFVPSYVKCVRMTGALSDKEINQTYVKVLSQMPYFRRSG GRDHIFVFPSGAGAHLFRSWATFLNRSIILTPEGDRTDKRGTSAFNTWKDIIIPGNVDDSMVKSDARAVQPIPLTKRKYLANFLGRAQGKAGRLQLVELA KQYPDKLESPVLKLSGPNKLGRIEYFKHLRNAKFCLAPRGESSWTLRFYESFFVECVPVILSDEVELPFQNVIDYGEISIKWPSSRIGPELLEYLESI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 427 Download |
| MRHHQACSRA HQVGALLLVA ATFLLTRLFD RLLLDTSSSA AINPGRPSSP ADLRIYVYAE 60 DEIQGLRALL RGRDGTITAA TCLKGQWGTQ VKIHQFLLKS RFRTFNKDQA NLFFVPSYVK 120 CVRMTGALSD KEINQTYVKV LSQMPYFRRS GGRDHIFVFP SGAGAHLFRS WATFLNRSII 180 LTPEGDRTDK RGTSAFNTWK DIIIPGNVDD SMVKSDARAV QPIPLTKRKY LANFLGRAQG 240 KAGRLQLVEL AKQYPDKLES PVLKLSGPNK LGRIEYFKHL RNAKFCLAPR GESSWTLRFY 300 ESFFVECVPV ILSDEVELPF QNVIDYGEIS IKWPSSRIGP ELLEYLESIS DERIEEMIGH 360 GRQMRCLWVY AADTEPCSAM SGILTELQKK VRRFHQSPET FWLHNRSIVN RDLIEFHSWR 420 TPVPLP* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 6.0e-47 | 49 | 349 | 308 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EAY93033.1 | 0 | 3 | 426 | 5 | 429 | hypothetical protein OsI_14833 [Oryza sativa Indica Group] |
| RefSeq | NP_001131485.1 | 0 | 1 | 426 | 1 | 426 | hypothetical protein LOC100192822 [Zea mays] |
| RefSeq | XP_002300942.1 | 0 | 7 | 426 | 22 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002458782.1 | 0 | 1 | 426 | 1 | 426 | hypothetical protein SORBIDRAFT_03g040220 [Sorghum bicolor] |
| RefSeq | XP_002526175.1 | 0 | 4 | 426 | 18 | 453 | catalytic, putative [Ricinus communis] |
