| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb03g040240.1 |
| Family | GT8 |
| Protein Properties | Length: 630 Molecular Weight: 69533.7 Isoelectric Point: 7.8834 |
| Chromosome | Chromosome/Scaffold: 3 Start: 67844850 End: 67846739 |
| Description | plant glycogenin-like starch initiation protein 1 |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT8 | 329 | 542 | 6.1e-39 |
| SRQAYATVLHSADAYVCGAIALAQSIRQSGSTRDLVALVDAHNVGAEHRAALAAAGWQVRLAPRIRNPHAEANAYNEWNYSKFRLWQLTDYEKVVFLDAD LLVLRNMDFLFEEAPELSATVNSGARFNSGVMVLEPCSCTFDLLMSGIHDIESYNGGDQGYLNEVFTWWHRLPRHVNFLKYVWAEGDRAAQARMLTAEPA EVHAVHYLGMKPWL | |||
| Full Sequence |
|---|
| Protein Sequence Length: 630 Download |
| MTGGVRKRTG FSKLLVVLLF FVCAIVIVAL LVRGNGCCVV VQVAVLPRIT SVGSSWDASP 60 TATTQSGKTI IPATSTRGAS SPAHDLQEDS EAVSASEEEE APAAAAAPYA ADSRWNIQWE 120 SVASVLSSFS SNGTGRRGIA RVGLLNFNSS EVARWTSTLP AADVRAVSLA PAADAVTWQA 180 LYPNWIDEES NRSSCPTLPN PDAAPHHHNF DLVAVKLPCR GQDWSRDVRR LHLQLAAAKL 240 TLHGSSSSSS KAGMVLILSE SGCLPLPNLF PCKHLFARRG HAFLYRPEAT YLRHRLNLPV 300 GSCQLAVPFL RPSPTKLPSA TPPGTSRTSR QAYATVLHSA DAYVCGAIAL AQSIRQSGST 360 RDLVALVDAH NVGAEHRAAL AAAGWQVRLA PRIRNPHAEA NAYNEWNYSK FRLWQLTDYE 420 KVVFLDADLL VLRNMDFLFE EAPELSATVN SGARFNSGVM VLEPCSCTFD LLMSGIHDIE 480 SYNGGDQGYL NEVFTWWHRL PRHVNFLKYV WAEGDRAAQA RMLTAEPAEV HAVHYLGMKP 540 WLCYRDYDCN WNVAELRRFA SDEAHARWWA VHDRIEPAEL RDRFCALPTS HMEVLEQQRR 600 EAATVNAPDG HWNRTITDPR RRIKAHYHH* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00505 | Glyco_transf_8 | 9.0e-12 | 331 | 541 | 247 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. | ||
| cd06914 | GT8_GNT1 | 5.0e-14 | 333 | 541 | 243 | + GNT1 is a fungal enzyme that belongs to the GT 8 family. N-acetylglucosaminyltransferase is a fungal enzyme that catalyzes the addition of N-acetyl-D-glucosamine to mannotetraose side chains by an alpha 1-2 linkage during the synthesis of mannan. The N-acetyl-D-glucosamine moiety in mannan plays a role in the attachment of mannan to asparagine residues in proteins. The mannotetraose and its N-acetyl-D-glucosamine derivative side chains of mannan are the principle immunochemical determinants on the cell surface. N-acetylglucosaminyltransferase is a member of glycosyltransferase family 8, which are, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed, retaining glycosyltransferases. | ||
| PLN00176 | PLN00176 | 2.0e-16 | 314 | 573 | 327 | + galactinol synthase | ||
| pfam01501 | Glyco_transf_8 | 7.0e-39 | 334 | 544 | 255 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. | ||
| cd02537 | GT8_Glycogenin | 5.0e-75 | 331 | 573 | 252 | + Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen. Glycogenin initiates the biosynthesis of glycogen by incorporating glucose residues through a self-glucosylation reaction at a Tyr residue, and then acts as substrate for chain elongation by glycogen synthase and branching enzyme. It contains a conserved DxD motif and an N-terminal beta-alpha-beta Rossmann-like fold that are common to the nucleotide-binding domains of most glycosyltransferases. The DxD motif is essential for coordination of the catalytic divalent cation, most commonly Mn2+. Glycogenin can be classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. It is placed in glycosyltransferase family 8 which includes lipopolysaccharide glucose and galactose transferases and galactinol synthases. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016757 | transferase activity, transferring glycosyl groups |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAS90653.1 | 0 | 116 | 623 | 146 | 638 | putative glycogenin [Oryza sativa Japonica Group] |
| GenBank | ACR37754.1 | 0 | 116 | 620 | 16 | 509 | unknown [Zea mays] |
| GenBank | EEC79261.1 | 0 | 116 | 623 | 146 | 638 | hypothetical protein OsI_20036 [Oryza sativa Indica Group] |
| GenBank | EEE63788.1 | 0 | 116 | 623 | 159 | 651 | hypothetical protein OsJ_18611 [Oryza sativa Japonica Group] |
| RefSeq | XP_002458785.1 | 0 | 1 | 629 | 1 | 629 | hypothetical protein SORBIDRAFT_03g040240 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1zcv_A | 2e-20 | 323 | 541 | 16 | 240 | A Chain A, Apo Form Of A Mutant Of Glycogenin In Which Asp159 Is Replaced By Asn |
| PDB | 3u2x_B | 4e-20 | 329 | 541 | 3 | 221 | A Chain A, Apo Form Of A Mutant Of Glycogenin In Which Asp159 Is Replaced By Asn |
| PDB | 3u2x_A | 4e-20 | 329 | 541 | 3 | 221 | A Chain A, Apo Form Of A Mutant Of Glycogenin In Which Asp159 Is Replaced By Asn |
| PDB | 3u2v_B | 4e-20 | 329 | 541 | 3 | 221 | A Chain A, Apo Form Of A Mutant Of Glycogenin In Which Asp159 Is Replaced By Asn |
| PDB | 3u2v_A | 4e-20 | 329 | 541 | 3 | 221 | A Chain A, Apo Form Of A Mutant Of Glycogenin In Which Asp159 Is Replaced By Asn |
