| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb03g040980.1 |
| Family | GT1 |
| Protein Properties | Length: 622 Molecular Weight: 68337.4 Isoelectric Point: 6.2073 |
| Chromosome | Chromosome/Scaffold: 3 Start: 68461633 End: 68472215 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT1 | 175 | 584 | 0 |
| VVGTRGDVQPFIALAKRLQEFGHYVRLATHVNFRTFVKSAGIDFYPLGGDPRVMAQYMTKNKGFFLAAPTEIAVQRKQLKEIIFSLLPACTEPDLDTGAP FRAQAIIANPPAYGHLHIAEALGAPLHIFFTFPWTPTNEFPHPLARMPQSATYRLSYLILDLIVWWGSRGFINDFRKKLNLPPIAYFSTYHGSISHLPTG YMWSPQLMPKPKDWGPLVDVVGYCFLNLGTKYQPPPELSQWLQQGPKPIYIGFGSMPLDDEKKVTAIILDALRETGQRGIISRGWGALGSFSEVPVDVFI LEDCPHDWLFPRCAAVVHHGGAGTTAAGLIAGCPTTVVPFFGDQFFWGERAHARGVGPAPIPIAELTVEALSNAIRFMLDPEVKSRTMELAIAIGNEDGV AAAVDAFHRH | |||
| Full Sequence |
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| Protein Sequence Length: 622 Download |
| MGINGEEWEG TVVDGGVRRR KGGAEGACLG ASSSFAEGTG EFVLRSMDAR FSGSVDDDEL 60 FVSSRQPVLG HSKSTAATSG TFKGQENVFV RSYSDRLLKC DLTLDMLSEN EKIKITERLV 120 KIQNDGTVEV DVTRSALVAS ELSEIDAFGY VPRDVEEVTP GITKSVPKLK IAILVVGTRG 180 DVQPFIALAK RLQEFGHYVR LATHVNFRTF VKSAGIDFYP LGGDPRVMAQ YMTKNKGFFL 240 AAPTEIAVQR KQLKEIIFSL LPACTEPDLD TGAPFRAQAI IANPPAYGHL HIAEALGAPL 300 HIFFTFPWTP TNEFPHPLAR MPQSATYRLS YLILDLIVWW GSRGFINDFR KKLNLPPIAY 360 FSTYHGSISH LPTGYMWSPQ LMPKPKDWGP LVDVVGYCFL NLGTKYQPPP ELSQWLQQGP 420 KPIYIGFGSM PLDDEKKVTA IILDALRETG QRGIISRGWG ALGSFSEVPV DVFILEDCPH 480 DWLFPRCAAV VHHGGAGTTA AGLIAGCPTT VVPFFGDQFF WGERAHARGV GPAPIPIAEL 540 TVEALSNAIR FMLDPEVKSR TMELAIAIGN EDGVAAAVDA FHRHLPSELP LSPPAHVEEE 600 RIDFLQWFSR ALEKCCFPFN M* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR01426 | MGT | 3.0e-5 | 180 | 579 | 420 | + glycosyltransferase, MGT family. This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production [Cellular processes, Toxin production and resistance]. | ||
| pfam03033 | Glyco_transf_28 | 5.0e-33 | 171 | 315 | 145 | + Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities. | ||
| COG1819 | COG1819 | 5.0e-38 | 170 | 583 | 420 | + Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms] | ||
| cd03784 | GT1_Gtf_like | 7.0e-119 | 170 | 584 | 420 | + This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005975 | carbohydrate metabolic process |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| GO:0030259 | lipid glycosylation |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACG25324.1 | 0 | 1 | 621 | 1 | 621 | sterol 3-beta-glucosyltransferase [Zea mays] |
| GenBank | EEC71863.1 | 0 | 194 | 620 | 98 | 525 | hypothetical protein OsI_04568 [Oryza sativa Indica Group] |
| RefSeq | NP_001044914.1 | 0 | 1 | 620 | 1 | 619 | Os01g0867600 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001132100.1 | 0 | 1 | 621 | 1 | 620 | hypothetical protein LOC100193516 [Zea mays] |
| RefSeq | XP_002456694.1 | 0 | 1 | 621 | 1 | 621 | hypothetical protein SORBIDRAFT_03g040980 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1iir_A | 8e-33 | 169 | 587 | 1 | 404 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
| PDB | 3h4t_A | 1e-31 | 169 | 577 | 1 | 374 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
| PDB | 3h4i_A | 1e-31 | 169 | 577 | 1 | 374 | A Chain A, Chimeric Glycosyltransferase For The Generation Of Novel Natural Products |
| PDB | 1rrv_B | 2e-31 | 169 | 565 | 1 | 380 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 1rrv_A | 2e-31 | 169 | 565 | 1 | 380 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| JG869846 | 291 | 179 | 469 | 0 |
| GT034671 | 322 | 243 | 563 | 0 |
| FL871916 | 262 | 282 | 543 | 0 |
| DT547914 | 322 | 187 | 507 | 0 |
| HO801427 | 412 | 199 | 608 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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