| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb03g042970.1 |
| Family | CE10 |
| Protein Properties | Length: 420 Molecular Weight: 45111.8 Isoelectric Point: 8.5421 |
| Chromosome | Chromosome/Scaffold: 3 Start: 70354910 End: 70357050 |
| Description | alpha/beta-Hydrolases superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| CE10 | 78 | 409 | 0 |
| SVRIFLPTPPPPTPHAHLLAHAPSRRASDPTPTPPAPAAGAPYRGYLPHAVASPRAAVSARRRLPIVVQFHGGGFVTGSNTAAANDAFCRRVAKLCDAIV VAVGYRLAPESRYPAAFEDGVKVLKWIAKQANLAMMTKVGGGVDTFGASTVEPWIAAHGDPARCVLLGASCGANIADYVTRKVVEDGKPFDPIKVVAQVL MYPFFIGSVPTHSEIRLANSYFYDKSTCLLAWRLFLSEKEFNLDHPAANPLAPGRGGPPLKCMPPTLTVIAEHDWMRDRAIAYSEELRKVNVDSPVLDYK DTVHEFATLDVFLKTPQAQACAEDIAIWMKKY | |||
| Full Sequence |
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| Protein Sequence Length: 420 Download |
| MPSVGVKIYS VFFKLFLRHR LQSLAAAAAA AGDNLDSAAF GVSCRPDEAT APPNPAFSAS 60 ADGVASKDLH IDPNSSLSVR IFLPTPPPPT PHAHLLAHAP SRRASDPTPT PPAPAAGAPY 120 RGYLPHAVAS PRAAVSARRR LPIVVQFHGG GFVTGSNTAA ANDAFCRRVA KLCDAIVVAV 180 GYRLAPESRY PAAFEDGVKV LKWIAKQANL AMMTKVGGGV DTFGASTVEP WIAAHGDPAR 240 CVLLGASCGA NIADYVTRKV VEDGKPFDPI KVVAQVLMYP FFIGSVPTHS EIRLANSYFY 300 DKSTCLLAWR LFLSEKEFNL DHPAANPLAP GRGGPPLKCM PPTLTVIAEH DWMRDRAIAY 360 SEELRKVNVD SPVLDYKDTV HEFATLDVFL KTPQAQACAE DIAIWMKKYI SLRGHEFSY* 420 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG2272 | PnbA | 5.0e-5 | 141 | 253 | 126 | + Carboxylesterase type B [Lipid metabolism] | ||
| cd00312 | Esterase_lipase | 1.0e-7 | 141 | 250 | 119 | + Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These catalytic residues are responsible for the nucleophilic attack on the carbonyl carbon atom of the ester bond. In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate. | ||
| PRK10162 | PRK10162 | 5.0e-9 | 143 | 225 | 86 | + acetyl esterase; Provisional | ||
| COG0657 | Aes | 7.0e-30 | 141 | 403 | 263 | + Esterase/lipase [Lipid metabolism] | ||
| pfam07859 | Abhydrolase_3 | 2.0e-59 | 144 | 384 | 241 | + alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008152 | metabolic process |
| GO:0016787 | hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EAY76860.1 | 0 | 1 | 419 | 1 | 410 | hypothetical protein OsI_04819 [Oryza sativa Indica Group] |
| RefSeq | NP_001045117.1 | 0 | 1 | 419 | 1 | 410 | Os01g0902300 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001142141.1 | 0 | 1 | 419 | 1 | 418 | hypothetical protein LOC100274306 [Zea mays] |
| RefSeq | XP_002267130.1 | 0 | 1 | 419 | 1 | 425 | PREDICTED: hypothetical protein isoform 2 [Vitis vinifera] |
| RefSeq | XP_002458935.1 | 0 | 1 | 419 | 1 | 419 | hypothetical protein SORBIDRAFT_03g042970 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3ed1_F | 6e-34 | 55 | 366 | 53 | 310 | A Chain A, The Crystal Structure Of Tnf Family Member Eda-A2 |
| PDB | 3ed1_E | 6e-34 | 55 | 366 | 53 | 310 | A Chain A, The Crystal Structure Of Tnf Family Member Eda-A2 |
| PDB | 3ed1_D | 6e-34 | 55 | 366 | 53 | 310 | A Chain A, The Crystal Structure Of Tnf Family Member Eda-A2 |
| PDB | 3ed1_C | 6e-34 | 55 | 366 | 53 | 310 | A Chain A, The Crystal Structure Of Tnf Family Member Eda-A2 |
| PDB | 3ed1_B | 6e-34 | 55 | 366 | 53 | 310 | A Chain A, The Crystal Structure Of Tnf Family Member Eda-A2 |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| formononetin biosynthesis | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| formononetin biosynthesis | RXN-3625 | - | 2,7-dihydroxy-4'-methoxyisoflavanone dehydratase |
| isoflavonoid biosynthesis I | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-3303 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-5502 | - | 2,7,5-trihydroxy-4'-methoxyisoflavanone dehydratase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| ES789976 | 300 | 141 | 420 | 0 |
| JG955414 | 219 | 202 | 420 | 0 |
| CT861358 | 245 | 175 | 419 | 0 |
| EB438845 | 280 | 159 | 420 | 0 |
| DT485343 | 270 | 154 | 420 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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